In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics]
Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C.
The American Society for Microbiology (ASM)
Published 2018
The American Society for Microbiology (ASM)
Published 2018
| Publication Date: |
2018-03-28
|
|---|---|
| Publisher: |
The American Society for Microbiology (ASM)
|
| Print ISSN: |
0066-4804
|
| Electronic ISSN: |
1098-6596
|
| Topics: |
Biology
Medicine
|
| Published by: |
| _version_ | 1836398864707354625 |
|---|---|
| autor | Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. |
| beschreibung | Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the in vitro activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC 90 values of 1 to 8 μg/ml against Bacteroides spp., 0.5 μg/ml against Clostridium difficile , Prevotella spp., and Porphyromonas asaccharolytica , 1 μg/ml against Peptostreptococcus spp., and 16 μg/ml against Clostridium perfringens . |
| citation_standardnr | 6218836 |
| datenlieferant | ipn_articles |
| feed_id | 515 |
| feed_publisher | The American Society for Microbiology (ASM) |
| feed_publisher_url | http://www.asm.org/ |
| insertion_date | 2018-03-28 |
| journaleissn | 1098-6596 |
| journalissn | 0066-4804 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | The American Society for Microbiology (ASM) |
| quelle | Antimicrobial Agents and Chemotherapy |
| relation | http://aac.asm.org/cgi/content/short/62/4/e00047-18?rss=1 |
| search_space | articles |
| shingle_author_1 | Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. |
| shingle_author_2 | Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. |
| shingle_author_3 | Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. |
| shingle_author_4 | Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. |
| shingle_catch_all_1 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the in vitro activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC 90 values of 1 to 8 μg/ml against Bacteroides spp., 0.5 μg/ml against Clostridium difficile , Prevotella spp., and Porphyromonas asaccharolytica , 1 μg/ml against Peptostreptococcus spp., and 16 μg/ml against Clostridium perfringens . Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. The American Society for Microbiology (ASM) 0066-4804 00664804 1098-6596 10986596 |
| shingle_catch_all_2 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the in vitro activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC 90 values of 1 to 8 μg/ml against Bacteroides spp., 0.5 μg/ml against Clostridium difficile , Prevotella spp., and Porphyromonas asaccharolytica , 1 μg/ml against Peptostreptococcus spp., and 16 μg/ml against Clostridium perfringens . Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. The American Society for Microbiology (ASM) 0066-4804 00664804 1098-6596 10986596 |
| shingle_catch_all_3 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the in vitro activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC 90 values of 1 to 8 μg/ml against Bacteroides spp., 0.5 μg/ml against Clostridium difficile , Prevotella spp., and Porphyromonas asaccharolytica , 1 μg/ml against Peptostreptococcus spp., and 16 μg/ml against Clostridium perfringens . Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. The American Society for Microbiology (ASM) 0066-4804 00664804 1098-6596 10986596 |
| shingle_catch_all_4 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the in vitro activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC 90 values of 1 to 8 μg/ml against Bacteroides spp., 0.5 μg/ml against Clostridium difficile , Prevotella spp., and Porphyromonas asaccharolytica , 1 μg/ml against Peptostreptococcus spp., and 16 μg/ml against Clostridium perfringens . Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C. The American Society for Microbiology (ASM) 0066-4804 00664804 1098-6596 10986596 |
| shingle_title_1 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] |
| shingle_title_2 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] |
| shingle_title_3 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] |
| shingle_title_4 | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] |
| timestamp | 2025-06-30T23:33:51.637Z |
| titel | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] |
| titel_suche | In Vitro Activities of Omadacycline and Comparators against Anaerobic Bacteria [Clinical Therapeutics] |
| topic | W WW-YZ |
| uid | ipn_articles_6218836 |