PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3K{alpha} Inhibitors

Croessmann, S., Sheehan, J. H., Lee, K.-m., Sliwoski, G., He, J., Nagy, R., Riddle, D., Mayer, I. A., Balko, J. M., Lanman, R., Miller, V. A., Cantley, L. C., Meiler, J., Arteaga, C. L.
The American Association for Cancer Research (AACR)
Published 2018