Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese

Publication Date:
2018-03-09
Publisher:
Wiley-Blackwell
Print ISSN:
0007-0963
Electronic ISSN:
1365-2133
Topics:
Medicine
Published by:
_version_ 1836398834610077696
autor L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
beschreibung Systemic lupus erythematosus (SLE) is a common prototypic autoimmune disease with substantial genetic predispositions. It is more prevalent in Asians than in Caucasians. Genome wide association studies (GWAS) have discovered more than 80 genetic loci for the risk of SLE 1 , which improve the understanding of SLE etiology and provide potential therapeutic targets. However, each GWAS finding only confers a relatively small effect, and they in total cannot fully explain SLE heritability, suggesting more genetic variants are yet to be discovered. This article is protected by copyright. All rights reserved.
citation_standardnr 6198178
datenlieferant ipn_articles
feed_id 5432
feed_publisher Wiley-Blackwell
feed_publisher_url http://www.wiley.com/wiley-blackwell
insertion_date 2018-03-09
journaleissn 1365-2133
journalissn 0007-0963
publikationsjahr_anzeige 2018
publikationsjahr_facette 2018
publikationsjahr_intervall 7984:2015-2019
publikationsjahr_sort 2018
publisher Wiley-Blackwell
quelle British Journal of Dermatology
relation http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fbjd.16500
search_space articles
shingle_author_1 L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
shingle_author_2 L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
shingle_author_3 L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
shingle_author_4 L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
shingle_catch_all_1 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
Systemic lupus erythematosus (SLE) is a common prototypic autoimmune disease with substantial genetic predispositions. It is more prevalent in Asians than in Caucasians. Genome wide association studies (GWAS) have discovered more than 80 genetic loci for the risk of SLE 1 , which improve the understanding of SLE etiology and provide potential therapeutic targets. However, each GWAS finding only confers a relatively small effect, and they in total cannot fully explain SLE heritability, suggesting more genetic variants are yet to be discovered. This article is protected by copyright. All rights reserved.
L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_catch_all_2 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
Systemic lupus erythematosus (SLE) is a common prototypic autoimmune disease with substantial genetic predispositions. It is more prevalent in Asians than in Caucasians. Genome wide association studies (GWAS) have discovered more than 80 genetic loci for the risk of SLE 1 , which improve the understanding of SLE etiology and provide potential therapeutic targets. However, each GWAS finding only confers a relatively small effect, and they in total cannot fully explain SLE heritability, suggesting more genetic variants are yet to be discovered. This article is protected by copyright. All rights reserved.
L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_catch_all_3 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
Systemic lupus erythematosus (SLE) is a common prototypic autoimmune disease with substantial genetic predispositions. It is more prevalent in Asians than in Caucasians. Genome wide association studies (GWAS) have discovered more than 80 genetic loci for the risk of SLE 1 , which improve the understanding of SLE etiology and provide potential therapeutic targets. However, each GWAS finding only confers a relatively small effect, and they in total cannot fully explain SLE heritability, suggesting more genetic variants are yet to be discovered. This article is protected by copyright. All rights reserved.
L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_catch_all_4 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
Systemic lupus erythematosus (SLE) is a common prototypic autoimmune disease with substantial genetic predispositions. It is more prevalent in Asians than in Caucasians. Genome wide association studies (GWAS) have discovered more than 80 genetic loci for the risk of SLE 1 , which improve the understanding of SLE etiology and provide potential therapeutic targets. However, each GWAS finding only confers a relatively small effect, and they in total cannot fully explain SLE heritability, suggesting more genetic variants are yet to be discovered. This article is protected by copyright. All rights reserved.
L. Liu, X. Zuo, Z. Zhu, L. Wen, C. Yang, C. Zhu, L. Tang, Y. Cheng, M. Chen, F. Zhou, X. Zheng, W. Wang, X. Yin, H. Tang, L. Sun, S. Yang, Y. Sheng, Y. Cui, X. Zhang
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_title_1 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
shingle_title_2 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
shingle_title_3 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
shingle_title_4 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
timestamp 2025-06-30T23:33:22.389Z
titel Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
titel_suche Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese
topic WW-YZ
uid ipn_articles_6198178