Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases

Publication Date:
2018-02-27
Publisher:
Wiley-Blackwell
Print ISSN:
0007-0963
Electronic ISSN:
1365-2133
Topics:
Medicine
Published by:
_version_ 1836398815408553985
autor E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
beschreibung There are few studies specifically addressing the safety and efficacy of biologic treatments, especially anti TNF-alpha agents, in psoriatic patients with cirrhosis as such patients are usually excluded from prospective interventional studies. However, one should be aware that biologics are often prescribed in this particular population for several reasons. This is probably due to the fact that physicians are usually reluctant to prescribe conventional systemic treatment such as methotrexate or acitretine in psoriatic patients with liver abnormalities because of their liver toxicity. In addition, there is a general agreement that biologics have very few pharmacologic interaction with liver function and are not contraindicated in case of liver insufficiency. This article is protected by copyright. All rights reserved.
citation_standardnr 6176045
datenlieferant ipn_articles
feed_id 5432
feed_publisher Wiley-Blackwell
feed_publisher_url http://www.wiley.com/wiley-blackwell
insertion_date 2018-02-27
journaleissn 1365-2133
journalissn 0007-0963
publikationsjahr_anzeige 2018
publikationsjahr_facette 2018
publikationsjahr_intervall 7984:2015-2019
publikationsjahr_sort 2018
publisher Wiley-Blackwell
quelle British Journal of Dermatology
relation http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fbjd.16490
search_space articles
shingle_author_1 E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
shingle_author_2 E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
shingle_author_3 E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
shingle_author_4 E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
shingle_catch_all_1 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
There are few studies specifically addressing the safety and efficacy of biologic treatments, especially anti TNF-alpha agents, in psoriatic patients with cirrhosis as such patients are usually excluded from prospective interventional studies. However, one should be aware that biologics are often prescribed in this particular population for several reasons. This is probably due to the fact that physicians are usually reluctant to prescribe conventional systemic treatment such as methotrexate or acitretine in psoriatic patients with liver abnormalities because of their liver toxicity. In addition, there is a general agreement that biologics have very few pharmacologic interaction with liver function and are not contraindicated in case of liver insufficiency. This article is protected by copyright. All rights reserved.
E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_catch_all_2 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
There are few studies specifically addressing the safety and efficacy of biologic treatments, especially anti TNF-alpha agents, in psoriatic patients with cirrhosis as such patients are usually excluded from prospective interventional studies. However, one should be aware that biologics are often prescribed in this particular population for several reasons. This is probably due to the fact that physicians are usually reluctant to prescribe conventional systemic treatment such as methotrexate or acitretine in psoriatic patients with liver abnormalities because of their liver toxicity. In addition, there is a general agreement that biologics have very few pharmacologic interaction with liver function and are not contraindicated in case of liver insufficiency. This article is protected by copyright. All rights reserved.
E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_catch_all_3 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
There are few studies specifically addressing the safety and efficacy of biologic treatments, especially anti TNF-alpha agents, in psoriatic patients with cirrhosis as such patients are usually excluded from prospective interventional studies. However, one should be aware that biologics are often prescribed in this particular population for several reasons. This is probably due to the fact that physicians are usually reluctant to prescribe conventional systemic treatment such as methotrexate or acitretine in psoriatic patients with liver abnormalities because of their liver toxicity. In addition, there is a general agreement that biologics have very few pharmacologic interaction with liver function and are not contraindicated in case of liver insufficiency. This article is protected by copyright. All rights reserved.
E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_catch_all_4 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
There are few studies specifically addressing the safety and efficacy of biologic treatments, especially anti TNF-alpha agents, in psoriatic patients with cirrhosis as such patients are usually excluded from prospective interventional studies. However, one should be aware that biologics are often prescribed in this particular population for several reasons. This is probably due to the fact that physicians are usually reluctant to prescribe conventional systemic treatment such as methotrexate or acitretine in psoriatic patients with liver abnormalities because of their liver toxicity. In addition, there is a general agreement that biologics have very few pharmacologic interaction with liver function and are not contraindicated in case of liver insufficiency. This article is protected by copyright. All rights reserved.
E. Begon, N. Beneton, C. Poiraud, C. Droitcourt, C. Jacobzone, A. Vermersch-Langlin, V. Descamps, J. Perrot, A. Khemis, V. Pallure, A. C. Fougerousse, M. Sigal-Grinberg, J. C Schmutz, C. Goujon, Z. Reguiai
Wiley-Blackwell
0007-0963
00070963
1365-2133
13652133
shingle_title_1 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
shingle_title_2 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
shingle_title_3 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
shingle_title_4 Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
timestamp 2025-06-30T23:33:01.244Z
titel Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
titel_suche Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases
topic WW-YZ
uid ipn_articles_6176045