Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey

Publication Date:
2018-02-16
Publisher:
BMJ Publishing
Electronic ISSN:
2044-6055
Topics:
Medicine
Keywords:
Open access, Infectious diseases
Published by:
http://group.bmj.com/
_version_ 1836398797141311488
autor Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
beschreibung Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 Participants Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms. Primary and secondary outcome measures Resource use for CAP management. Results Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0–1 and Pneumonia Severity Index risk class I–II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%. Conclusions These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China. Trial registration number NCT02489578 ; Results.
citation_standardnr 6166002
datenlieferant ipn_articles
feed_id 151627
feed_publisher BMJ Publishing
feed_publisher_url http://group.bmj.com/
insertion_date 2018-02-16
journaleissn 2044-6055
publikationsjahr_anzeige 2018
publikationsjahr_facette 2018
publikationsjahr_intervall 7984:2015-2019
publikationsjahr_sort 2018
publisher BMJ Publishing
quelle BMJ Open
relation http://bmjopen.bmj.com/cgi/content/short/8/2/e018709?rss=1
schlagwort Open access, Infectious diseases
search_space articles
shingle_author_1 Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
shingle_author_2 Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
shingle_author_3 Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
shingle_author_4 Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
shingle_catch_all_1 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
Open access, Infectious diseases
Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 Participants Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms. Primary and secondary outcome measures Resource use for CAP management. Results Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0–1 and Pneumonia Severity Index risk class I–II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%. Conclusions These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China. Trial registration number NCT02489578 ; Results.
Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
BMJ Publishing
2044-6055
20446055
shingle_catch_all_2 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
Open access, Infectious diseases
Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 Participants Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms. Primary and secondary outcome measures Resource use for CAP management. Results Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0–1 and Pneumonia Severity Index risk class I–II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%. Conclusions These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China. Trial registration number NCT02489578 ; Results.
Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
BMJ Publishing
2044-6055
20446055
shingle_catch_all_3 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
Open access, Infectious diseases
Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 Participants Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms. Primary and secondary outcome measures Resource use for CAP management. Results Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0–1 and Pneumonia Severity Index risk class I–II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%. Conclusions These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China. Trial registration number NCT02489578 ; Results.
Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
BMJ Publishing
2044-6055
20446055
shingle_catch_all_4 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
Open access, Infectious diseases
Objectives To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China. Design This was a multicentre, retrospective, observational study. Setting 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 Participants Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms. Primary and secondary outcome measures Resource use for CAP management. Results Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0–1 and Pneumonia Severity Index risk class I–II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%. Conclusions These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China. Trial registration number NCT02489578 ; Results.
Chen, L., Zhou, F., Li, H., Xing, X., Han, X., Wang, Y., Zhang, C., Suo, L., Wang, J., Yu, G., Wang, G., Yao, X., Yu, H., Wang, L., Liu, M., Xue, C., Liu, B., Zhu, X., Li, Y., Xiao, Y., Cui, X., Li, L., Uyeki, T. M., Wang, C., Cao, B., CAP-China network
BMJ Publishing
2044-6055
20446055
shingle_title_1 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
shingle_title_2 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
shingle_title_3 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
shingle_title_4 Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
timestamp 2025-06-30T23:32:47.120Z
titel Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
titel_suche Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey
topic WW-YZ
uid ipn_articles_6166002