Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure–Activity and Structure–Property Relationship Studies

Raghupathi Neelarapu, Jordany R. Maignan, Cynthia L. Lichorowic, Andrii Monastyrskyi, Tina S. Mutka, Alexis N. La; Crue, Lynn D. Blake, Debora Casandra, Sherwin Mashkouri, Jeremy N. Burrows, Paul A. Willis, Dennis E. Kyle and Roman Manetsch
American Chemical Society (ACS)
Published 2018