3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography
E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld
Institute of Physics Publishing (IOP)
Published 2018
Institute of Physics Publishing (IOP)
Published 2018
| Publication Date: |
2018-02-01
|
|---|---|
| Publisher: |
Institute of Physics Publishing (IOP)
|
| Electronic ISSN: |
1748-0221
|
| Topics: |
Physics
|
| Published by: |
| _version_ | 1836398770980388864 |
|---|---|
| autor | E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld |
| beschreibung | The word "theranostic" derives from the fusion of two terms: therapeutic and diagnostic. It is a promising research field that aims to develop innovative therapies with high target specificity by exploiting the therapeutic and diagnostic properties, in particular for metal-based nanoparticles (NPs) developed to erase cancer. In the framework of a combined research program on low dose X-ray imaging and theranostic nanoparticles (NPs), high resolution Phase-Contrast Tomography images of mice organs injected with gadolinium and gold-NPs were acquired at the European Synchrotron Radiation Facility (ESRF). Both compounds are good X-ray contrast agents due to their high attenuation coefficient with respect to biological tissues, especially immediately above K-edge energy. X-ray tomography is a powerful non-invasive technique to image the 3D vasculature network in order to detect abnormalities. Phase contrast methods provide more detailed anatomical information with higher discriminati... |
| citation_standardnr | 6151076 |
| datenlieferant | ipn_articles |
| feed_id | 66992 |
| feed_publisher | Institute of Physics Publishing (IOP) |
| feed_publisher_url | http://www.iop.org/ |
| insertion_date | 2018-02-01 |
| journaleissn | 1748-0221 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | Institute of Physics Publishing (IOP) |
| quelle | Journal of Instrumentation |
| relation | http://iopscience.iop.org/1748-0221/13/01/C01049 |
| search_space | articles |
| shingle_author_1 | E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld |
| shingle_author_2 | E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld |
| shingle_author_3 | E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld |
| shingle_author_4 | E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld |
| shingle_catch_all_1 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography The word "theranostic" derives from the fusion of two terms: therapeutic and diagnostic. It is a promising research field that aims to develop innovative therapies with high target specificity by exploiting the therapeutic and diagnostic properties, in particular for metal-based nanoparticles (NPs) developed to erase cancer. In the framework of a combined research program on low dose X-ray imaging and theranostic nanoparticles (NPs), high resolution Phase-Contrast Tomography images of mice organs injected with gadolinium and gold-NPs were acquired at the European Synchrotron Radiation Facility (ESRF). Both compounds are good X-ray contrast agents due to their high attenuation coefficient with respect to biological tissues, especially immediately above K-edge energy. X-ray tomography is a powerful non-invasive technique to image the 3D vasculature network in order to detect abnormalities. Phase contrast methods provide more detailed anatomical information with higher discriminati... E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld Institute of Physics Publishing (IOP) 1748-0221 17480221 |
| shingle_catch_all_2 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography The word "theranostic" derives from the fusion of two terms: therapeutic and diagnostic. It is a promising research field that aims to develop innovative therapies with high target specificity by exploiting the therapeutic and diagnostic properties, in particular for metal-based nanoparticles (NPs) developed to erase cancer. In the framework of a combined research program on low dose X-ray imaging and theranostic nanoparticles (NPs), high resolution Phase-Contrast Tomography images of mice organs injected with gadolinium and gold-NPs were acquired at the European Synchrotron Radiation Facility (ESRF). Both compounds are good X-ray contrast agents due to their high attenuation coefficient with respect to biological tissues, especially immediately above K-edge energy. X-ray tomography is a powerful non-invasive technique to image the 3D vasculature network in order to detect abnormalities. Phase contrast methods provide more detailed anatomical information with higher discriminati... E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld Institute of Physics Publishing (IOP) 1748-0221 17480221 |
| shingle_catch_all_3 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography The word "theranostic" derives from the fusion of two terms: therapeutic and diagnostic. It is a promising research field that aims to develop innovative therapies with high target specificity by exploiting the therapeutic and diagnostic properties, in particular for metal-based nanoparticles (NPs) developed to erase cancer. In the framework of a combined research program on low dose X-ray imaging and theranostic nanoparticles (NPs), high resolution Phase-Contrast Tomography images of mice organs injected with gadolinium and gold-NPs were acquired at the European Synchrotron Radiation Facility (ESRF). Both compounds are good X-ray contrast agents due to their high attenuation coefficient with respect to biological tissues, especially immediately above K-edge energy. X-ray tomography is a powerful non-invasive technique to image the 3D vasculature network in order to detect abnormalities. Phase contrast methods provide more detailed anatomical information with higher discriminati... E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld Institute of Physics Publishing (IOP) 1748-0221 17480221 |
| shingle_catch_all_4 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography The word "theranostic" derives from the fusion of two terms: therapeutic and diagnostic. It is a promising research field that aims to develop innovative therapies with high target specificity by exploiting the therapeutic and diagnostic properties, in particular for metal-based nanoparticles (NPs) developed to erase cancer. In the framework of a combined research program on low dose X-ray imaging and theranostic nanoparticles (NPs), high resolution Phase-Contrast Tomography images of mice organs injected with gadolinium and gold-NPs were acquired at the European Synchrotron Radiation Facility (ESRF). Both compounds are good X-ray contrast agents due to their high attenuation coefficient with respect to biological tissues, especially immediately above K-edge energy. X-ray tomography is a powerful non-invasive technique to image the 3D vasculature network in order to detect abnormalities. Phase contrast methods provide more detailed anatomical information with higher discriminati... E. Longo, A. Bravin, F. Brun, I. Bukreeva, A. Cedola, M. Fratini, X. Le Guevel, L. Massimi, L. Sancey, O. Tillement, P. Zeitoun and O. de La Rochefoucauld Institute of Physics Publishing (IOP) 1748-0221 17480221 |
| shingle_title_1 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography |
| shingle_title_2 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography |
| shingle_title_3 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography |
| shingle_title_4 | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography |
| timestamp | 2025-06-30T23:32:22.123Z |
| titel | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography |
| titel_suche | 3D map of theranostic nanoparticles distribution in mice brain and liver by means of X-ray Phase Contrast Tomography |
| topic | U |
| uid | ipn_articles_6151076 |