A Numerical Model of Exchange Chromatography Through 3D Lattice Structures
| Publication Date: |
2018-01-31
|
|---|---|
| Publisher: |
Wiley-Blackwell
|
| Print ISSN: |
0001-1541
|
| Electronic ISSN: |
1547-5905
|
| Topics: |
Chemistry and Pharmacology
Process Engineering, Biotechnology, Nutrition Technology
|
| Published by: |
| _version_ | 1836398767780134912 |
|---|---|
| autor | Maher Salloum, David B. Robinson |
| beschreibung | Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. The front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array. This article is protected by copyright. All rights reserved. |
| citation_standardnr | 6149340 |
| datenlieferant | ipn_articles |
| feed_copyright | The American Institute of Chemical Engineers (AIChE) |
| feed_copyright_url | http://www.aiche.org/ |
| feed_id | 40392 |
| feed_publisher | Wiley-Blackwell |
| feed_publisher_url | http://www.wiley.com/wiley-blackwell |
| insertion_date | 2018-01-31 |
| journaleissn | 1547-5905 |
| journalissn | 0001-1541 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | Wiley-Blackwell |
| quelle | AIChE Journal |
| relation | http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Faic.16108 |
| search_space | articles |
| shingle_author_1 | Maher Salloum, David B. Robinson |
| shingle_author_2 | Maher Salloum, David B. Robinson |
| shingle_author_3 | Maher Salloum, David B. Robinson |
| shingle_author_4 | Maher Salloum, David B. Robinson |
| shingle_catch_all_1 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. The front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array. This article is protected by copyright. All rights reserved. Maher Salloum, David B. Robinson Wiley-Blackwell 0001-1541 00011541 1547-5905 15475905 |
| shingle_catch_all_2 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. The front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array. This article is protected by copyright. All rights reserved. Maher Salloum, David B. Robinson Wiley-Blackwell 0001-1541 00011541 1547-5905 15475905 |
| shingle_catch_all_3 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. The front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array. This article is protected by copyright. All rights reserved. Maher Salloum, David B. Robinson Wiley-Blackwell 0001-1541 00011541 1547-5905 15475905 |
| shingle_catch_all_4 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. The front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array. This article is protected by copyright. All rights reserved. Maher Salloum, David B. Robinson Wiley-Blackwell 0001-1541 00011541 1547-5905 15475905 |
| shingle_title_1 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures |
| shingle_title_2 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures |
| shingle_title_3 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures |
| shingle_title_4 | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures |
| timestamp | 2025-06-30T23:32:19.408Z |
| titel | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures |
| titel_suche | A Numerical Model of Exchange Chromatography Through 3D Lattice Structures |
| topic | V ZM |
| uid | ipn_articles_6149340 |