No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG
S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov
Wiley-Blackwell
Published 2018
Wiley-Blackwell
Published 2018
Publication Date: |
2018-01-30
|
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Publisher: |
Wiley-Blackwell
|
Print ISSN: |
0007-0963
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Electronic ISSN: |
1365-2133
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Topics: |
Medicine
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Published by: |
_version_ | 1836398766045790211 |
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autor | S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov |
beschreibung | Ultraviolet B (UVB) irradiation-induced skin inflammation leads to epidermal depletion of Langerhans cells (LCs), which is followed by a rapid influx of monocytes.(1) Approximately 10% of Northern Europeans carry loss-of-function mutations in the filaggrin gene ( FLG ) which cause partial or complete lack of epidermal filaggrin and filaggrin metabolites.(2) Deficit of the filaggrin metabolite trans -urocanic acid has been shown to cause an increased keratinocyte photosensitivity to UVB irradiation in human skin models.(3) This article is protected by copyright. All rights reserved. |
citation_standardnr | 6148420 |
datenlieferant | ipn_articles |
feed_id | 5432 |
feed_publisher | Wiley-Blackwell |
feed_publisher_url | http://www.wiley.com/wiley-blackwell |
insertion_date | 2018-01-30 |
journaleissn | 1365-2133 |
journalissn | 0007-0963 |
publikationsjahr_anzeige | 2018 |
publikationsjahr_facette | 2018 |
publikationsjahr_intervall | 7984:2015-2019 |
publikationsjahr_sort | 2018 |
publisher | Wiley-Blackwell |
quelle | British Journal of Dermatology |
relation | http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fbjd.16394 |
search_space | articles |
shingle_author_1 | S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov |
shingle_author_2 | S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov |
shingle_author_3 | S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov |
shingle_author_4 | S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov |
shingle_catch_all_1 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG Ultraviolet B (UVB) irradiation-induced skin inflammation leads to epidermal depletion of Langerhans cells (LCs), which is followed by a rapid influx of monocytes.(1) Approximately 10% of Northern Europeans carry loss-of-function mutations in the filaggrin gene ( FLG ) which cause partial or complete lack of epidermal filaggrin and filaggrin metabolites.(2) Deficit of the filaggrin metabolite trans -urocanic acid has been shown to cause an increased keratinocyte photosensitivity to UVB irradiation in human skin models.(3) This article is protected by copyright. All rights reserved. S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov Wiley-Blackwell 0007-0963 00070963 1365-2133 13652133 |
shingle_catch_all_2 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG Ultraviolet B (UVB) irradiation-induced skin inflammation leads to epidermal depletion of Langerhans cells (LCs), which is followed by a rapid influx of monocytes.(1) Approximately 10% of Northern Europeans carry loss-of-function mutations in the filaggrin gene ( FLG ) which cause partial or complete lack of epidermal filaggrin and filaggrin metabolites.(2) Deficit of the filaggrin metabolite trans -urocanic acid has been shown to cause an increased keratinocyte photosensitivity to UVB irradiation in human skin models.(3) This article is protected by copyright. All rights reserved. S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov Wiley-Blackwell 0007-0963 00070963 1365-2133 13652133 |
shingle_catch_all_3 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG Ultraviolet B (UVB) irradiation-induced skin inflammation leads to epidermal depletion of Langerhans cells (LCs), which is followed by a rapid influx of monocytes.(1) Approximately 10% of Northern Europeans carry loss-of-function mutations in the filaggrin gene ( FLG ) which cause partial or complete lack of epidermal filaggrin and filaggrin metabolites.(2) Deficit of the filaggrin metabolite trans -urocanic acid has been shown to cause an increased keratinocyte photosensitivity to UVB irradiation in human skin models.(3) This article is protected by copyright. All rights reserved. S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov Wiley-Blackwell 0007-0963 00070963 1365-2133 13652133 |
shingle_catch_all_4 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG Ultraviolet B (UVB) irradiation-induced skin inflammation leads to epidermal depletion of Langerhans cells (LCs), which is followed by a rapid influx of monocytes.(1) Approximately 10% of Northern Europeans carry loss-of-function mutations in the filaggrin gene ( FLG ) which cause partial or complete lack of epidermal filaggrin and filaggrin metabolites.(2) Deficit of the filaggrin metabolite trans -urocanic acid has been shown to cause an increased keratinocyte photosensitivity to UVB irradiation in human skin models.(3) This article is protected by copyright. All rights reserved. S. Simonsen, C. M. Bonefeld, J. P. Thyssen, A. T. Christiansen, C. Geisler, L. Skov Wiley-Blackwell 0007-0963 00070963 1365-2133 13652133 |
shingle_title_1 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG |
shingle_title_2 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG |
shingle_title_3 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG |
shingle_title_4 | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG |
timestamp | 2025-06-30T23:32:17.817Z |
titel | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG |
titel_suche | No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG |
topic | WW-YZ |
uid | ipn_articles_6148420 |