Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Michael L. Vazquez, Neelu Kaila, Joseph W. Strohbach, John D. Trzupek, Matthew F. Brown, Mark E. Flanagan, Mark J. Mitton-Fry, Timothy A. Johnson, Ruth E. Ten; Brink, Eric P. Arnold, Arindrajit Basak, Steven E. Heasley, Soojin Kwon, Jonathan Langille, Mihir D. Parikh, Sarah H. Griffin, Jeffrey M. Casavant, Brian A. Duclos, Ashley E. Fenwick, Thomas M. Harris, Seungil Han, Nicole Caspers, Martin E. Dowty, Xin Yang, Mary Ellen Banker, Martin Hegen, Peter T. Symanowicz, Li Li, Lu Wang, Tsung H. Lin, Jason Jussif, James D. Clark, Jean-Baptiste Telliez, Ralph P. Robinson and Ray Unwalla
American Chemical Society (ACS)
Published 2018