Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin [Articles]

Gu, H., Dutreix, C., Rebello, S., Ouatas, T., Wang, L., Chun, D. Y., Einolf, H. J., He, H.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018
Publication Date:
2018-01-12
Publisher:
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Print ISSN:
0090-9556
Electronic ISSN:
1521-009X
Topics:
Chemistry and Pharmacology
Medicine
Published by: