Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio [Articles]

Obach, R. S., Lin, J., Kimoto, E., Duvvuri, S., Nicholas, T., Kadar, E. P., Tremaine, L. M., Sawant-Basak, A.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018
Publication Date:
2018-01-12
Publisher:
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Print ISSN:
0090-9556
Electronic ISSN:
1521-009X
Topics:
Chemistry and Pharmacology
Medicine
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