Search Results - "International Ophthalmology"

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Summary The Acuityscope projects an image of a three bar resolution test target onto the patient's retina, where it is viewed and read by an observer. The test target consists of a series of three bar targets varying in size on a logarithmic scale. Individual targets are identified in the projected image by Bailey-Lovie log visual acuity equivalents. The projected image includes only those target sizes which are useful for estimating visual acuity.The Acuityscope is used for assessing the quality of retinal image formation, and is thus able to differentiate between poor visual acuity due to image degradation, (e.g. cataract or corneal disease) and poor visual acuity due to image handling defects (e.g. retinal or optic nerve disease). The use of the instrument is relevant to both clinical situations (e.g. pre-operative assessment of opacification of optical media) and expermental situations (e.g. clinical trials).

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1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

dexamethasone ; intravitreal ; vitrectomy

Springer Online Journal Archives 1860-2000

Medicine

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1573-2630

anterior ischemic optic neuropathy (AION) ; cavernous sinus thrombosis (CST) ; central retinal artery occlusion (CRAO) ; sepsis

Springer Online Journal Archives 1860-2000

Medicine

Abstract An unusual case of bilateral blindness secondary to a cavernous sinus thrombosis is reported. A woman who had undergone reconstructive surgery after tumor resection of the floor of the mouth, was readmitted 1 month later with bilateral proptosis and signs of sepsis. There were no complaints of blurred vision. A CT-scan of the orbits demonstrated a bilateral cavernous sinus thrombosis (CST) secondary to an infection at the skull base behind the myocataneous flap. A few days later she became blind, due to bilateral central retinal artery occlusion and anterior ischemic optic neuropathy. The general critical condition improved with intensive AB treatment. The patient recovered well without neurological defects apart from her permanent bilateral blindness. There were no signs of tumor recurrence. To our knowledge, this is the first documented case of bilateral blindness in a patient suffering from CST.

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1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

corneal endothelium ; elliptical geometry ; high gas-permeability ; pleomorphism ; polymegathism ; rigid contact lens

Springer Online Journal Archives 1860-2000

Medicine

Abstract The influence of the permanent wear of rigid high Dk-lenses (nominal Dk 71 or 92) with elliptical geometry on the corneal endothelium was assessed. For this purpose the endothelium of 16 patients was compared by specular microscopy before and after the permanent wear. The wearing time of the lenses varied between 7 and 24 months. Computerized morphometric analysis of the photographs revealed that the variability in cell size (polymegathism) and in cell shape (pleomorphism) did not change during the wearing period. It is suggested that this is due to the high gas-permeability and the elliptical geometry of the contact lenses.

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1573-2630

choroidal melanoma ; echography ; B-mode ; choroidal excavation ; histology

Springer Online Journal Archives 1860-2000

Medicine

Abstract The B-mode images of 32 patients affected with a malignant melanoma of the choroid were studied, in particular with respect to choroidal excavation. The degree of visibility of choroidal excavation at the B-scan was compared with the thickness of the choroid, scleral invasion, vascularisation, retinal detachment and the reflectivity of the tumour. Non of these histological and echographical features appeared to be significantly related to the degree of the visibility of choroidal excavation. Also the condition of the choroid was studied. At examination of all the histological sections no choroid was found between tumour and sclera. This implies that choroidal excavation should be visible at echograms in every case instead of only in 75% of the cases as was found for our series.

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1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

epithelial fingerprint lines ; leukoplakia of the cornea ; epithelial dysplasia

Springer Online Journal Archives 1860-2000

Medicine

Abstract Opacities in association with fingerprint patterns of the epithelium were seen in the upper half of the right cornea of a 52-year-old patient complaining of decreased vision. Removal of the corneal epithelium from the involved area resulted in visual improvement and normalization of corneal appearance. Histological examination of the removed epithelium failed to reveal the typical intraepithelial formation of basement membrane invaginations even in the areas corresponding to the fingerprint patterns. Moderate to severe degree of atypia were seen in the epithelial cells. No abnormalities were observed in 3 conjunctival specimens excised at the time of epithelial removal. The diagnosis of corneal dysplasia (leukoplakia) was made. Our report is the first description of epithelial fingerprint patterns of the cornea associated with leukoplakia.

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1573-2630

tear fluid ; epidermal growth factor ; wound healing

Springer Online Journal Archives 1860-2000

Medicine

Abstract This minireview deals with the presence of epidermal growth factor (EGF) in human tear fluid. It explains the occurrence of EGF in tear fluid, the origin of EGF and its dependency on tear fluid dynamics. The alterations in tear fluid EGF concentrations that occur during diseases of the ocular surface are described and discussed in the context of the current knowledge about the interaction between EGF and EGF receptors. The possible clinical implications of topical treatment with EGF are considered.

Electronic Resource

1573-2630

piroxicam ; streptozocin ; blood-retina barrier ; vitreous fluorophotometry ; platelet aggregation

Springer Online Journal Archives 1860-2000

Medicine

Abstract The effect of piroxicam on the blood-retina barrier was evaluated in rats with experimentally induced diabetes. Diabetes was induced in rats by intraperitoneal injection of streptozocin (STZ). Diabetic rats were divided into two equal groups: those treated with piroxicam, a long-acting platelet inhibitor, and an untreated control group. Vitreous fluorophotometry (VFP) was performed both before and two weeks after induction of diabetes and piroxicam intake. Streptozocin-induced diabetes caused an alteration in the blood-retinal barrier evidenced by an increase in vitreous fluorescein concentration in diabetic rats compared with normal rats. Piroxicam intake did not lead to significant change in vitreous fluorescein concentrations. However, the examination had to be terminated at two weeks because of cataract formation. The piroxicam treated group showed less incidence of lens opacity formation (59.1% compared to 81.8% in the untreated group, p = 0.0006). Piroxicam administration appears to protect the diabetic rat eye against lens opacification.

Electronic Resource

1573-2630

ichthyosis ; recessive ; lamellar ; ectropion ; conservative management

Springer Online Journal Archives 1860-2000

Medicine

Abstract This report presents a Libyan child with congenital ichthyosis of the recessive lamellar variety complicated by severe ectropion of both upper and lower eyelids. Over a period of 12 months the degree of ectropion diminished and the anterior segments of the eyes were preserved using regular lubricating drops, vitamin A ointment and intermittent topical antibiotic therapy. Despite the pronounced initial upper eyelid ectropion no surgery was required to relieve the ectropion or prevent corneal exposure.

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1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Electronic Resource

1573-2630

dacryostenosis ; diagnostics ; digital dacryocystography ; videodocumentation

Springer Online Journal Archives 1860-2000

Medicine

Abstract The digital dacryocystography proved to be the optimum method of X-ray diagnostics in obstructions of the lacrimal pathways. The examination was performed with a computer controlled X-ray unit with a C-arc coupled to an image intensifier tv-system. In the study the advantages of this technique were combined with the advantages of modern videotechnique. A nonionic water soluble contrast medium was used. The bilateral contrast medium filling process was registrated and the findings were recorded on videotape concurrently. The videocassettes, marked with the data of the patients and the date of examination, are stored in a video-tape library. This provides an always repeatable diagnostic documentation and it is also an excellent base for scientific analyses. The technique and the results of the examinations, performed with 18 patients, are described.

Electronic Resource

1573-2630

Springer Online Journal Archives 1860-2000

Medicine

Summary The fluorescein angiographic findings immediately following a tear of the retinal pigment epithelium are presented and the mechanisms of fluid movement from the retina to the choroid are discussed. Our case represents a clinical correlate to recent experimental reports on fluid movement across the retinal pigment epithelium-Bruch's membrane complex.

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