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1Staff View Availability
Person(s): Trumble, William R. u.a.Type of Medium: UnknownPages: 2 Volumes (3750 S.) -
2Staff View Availability
Person(s): Schwan, Renate; Kohlhaas, Günter; Behrenberg, Angelika u.a.Type of Medium: UnknownPages: 126 S.ISBN: 3407320272Series Statement: Blickpunkt Hochschuldidaktik 107 -
3Sartori, E. ; Fallo, L. ; La Face, B. ; Bianchi, U.A. ; Pecorelli, S.
Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachussetts 02142, USA : Blackwell Science Inc.
Published 1995Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The question of whether surgical treatment in early-stage cervical cancer should be aggressive or restricted to less radical techniques is still controversial. To answer this question it was thought useful to investigate the correlation of parametrial lymph node metastases with extension and stage of disease. Two-hundred and sixty-three consecutive primary radical surgical procedures were performed in our institute in clinical stage IB or stage IIA cervical cancer. Positive parametrial nodes were found in 6.9% of cases: 5% in stage IB (3% in the proximal part of the parametrium and 2% in the distal part, near the pelvic wall) and 16.3% in stage IIA (7% proximal and 9.3% distal) (P = 0.0193). During a median follow-up period of 92 months, disease recurred in 17.1% and 17.6% of cases, in negative and positive parametria, respectively. The 5-year overall and disease-free survival rates were 80.4% and 81.6% for patients with negative and positive parametria, respectively. From this experience it is concluded that the extent of radical hysterectomy should be related to the extent of the disease on the basis of modern knowledge of the pattern of spread. The principal key to prognosis remains pelvic and paracavoaortic nodal status.Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1365-3040Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The objective of this investigation was to examine the effect of an elevated atmospheric CO2 partial pressure (pCO2) on the N-sink strength and performance of symbiotic N2 fixation in Trifolium repens L. cv. Milkanova. After initial growth under ambient pCO2 in a nitrogen-free nutrient solution, T. repens in the exponential growth stage was exposed to ambient and elevated pCO2 (35 and 60 Pa) and two levels of mineral N (N-free and 7·5 mol m–3 N) for 36 d in single pots filled with silica sand in growth chambers. Elevated pCO2 evoked a significant increase in biomass production from day 12 after the start of CO2 enrichment. For plants supplied with 7·5 mol m–3 N, the relative contribution of symbiotically fixed N (%Nsym) as opposed to N assimilated from mineral sources (15N-isotope-dilution method), dropped to 40%. However, in the presence of this high level of mineral N, %Nsym was unaffected by atmospheric pCO2 over the entire experimental period. In plants fully dependent on N2 fixation, the increase in N yield reflects a stimulation of symbiotic N2 fixation that was the result of the formation of more nodules rather than of higher specific N2 fixation. These results are discussed with regard to physiological processes governing symbiotic N2 fixation and to the response of symbiotic N2 fixation to elevated pCO2 in field-grown T. repens.Type of Medium: Electronic ResourceURL: -
5Galiano, Matthias ; Liu, Zhi Qiang ; Kalla, Roger ; Bohatschek, Marion ; Koppius, Andrea ; Gschwendtner, Andreas ; Xu, ShengLi ; Werner, Alexander ; Kloss, Christian U.A. ; Jones, Leonard L. ; Bluethmann, Horst ; Raivich, Gennadij
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Nerve injury triggers numerous changes in the injured neurons and surrounding non-neuronal cells. Of particular interest are molecular signals that play a role in the overall orchestration of this multifaceted cellular response. Here we investigated the function of interleukin-6 (IL6), a multifunctional neurotrophin and cytokine rapidly expressed in the injured nervous system, using the facial axotomy model in IL6-deficient mice and wild-type controls. Transgenic deletion of IL6 caused a massive decrease in the recruitment of CD3-positive T-lymphocytes and early microglial activation during the first 4 days after injury in the axotomized facial nucleus. This was accompanied by a more moderate reduction in peripheral regeneration at day 4, lymphocyte recruitment (day 14) and enhanced perikaryal sprouting (day 14). Motoneuron cell death, phagocytosis by microglial cells and recruitment of granulocytes and macrophages into injured peripheral nerve were not affected. In summary, IL6 lead to a variety of effects on the cellular response to neural trauma. However, the particularly strong actions on lymphocytes and microglia suggest that this cytokine plays a central role in the initiation of immune surveillance in the injured central nervous system.Type of Medium: Electronic ResourceURL: -
6Madden, U.A. ; Osweiler, G.D. ; Knipe, L. ; Beran, G.W. ; Beitz, D.C.
Oxford, UK : Blackwell Publishing Ltd
Published 1999Staff ViewISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Pork and mutton sausage-type mixes produced using Eubacterium coprostanoligenes with or without Lactobacillus as starter culture showed changes in pH, cholesterol and lipid content. Viability of E. coprostanoligenes was assessed by culturing samples from each treatment and analyzing for coprostanol, a cholesterol metabolite. The pH and/or cholesterol decreased (P 〈 0.05) in the sausage-type mixes inoculated with E. coprostanoligenes or Lactobacillus or their combinations. Variability in lipid content was observed among and within treatments. Very low (6.2 μg/g dry matter) concentrations of coprostanol were produced in sausage-mixes and cultures except when inoculated with 2.0 g of E. coprostanoligenes (from 8.2 to 130.6 μg/g dry matter).Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0011-2240Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0003-2697Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
9SHAH, PRASAD P. ; NAIR, MOHAN ; DHALL, ANIL ; VERMA, K.K. ; MIDHA, K.K. ; MOHAN, J.C. ; KAUL, U.A. ; ARORA, R.
Oxford, UK : Blackwell Publishing Ltd
Published 2000Staff ViewISSN: 1540-8159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: False-positive exercise testing in patients with an accessory pathway has been described only in patients with manifest preexcitation during exercise. We describe a patient in whom marked ST-segment changes were seen during an exercise test in the absence of any preexcitation of the QRS complexes. The role of the accessory pathway in producing the ST changes was reaffirmed by absence of this abnormality following catheter ablation of the accessory pathway.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0005-2736Keywords: Microsome ; Mitochondrion ; Rough endoplasmic reticulumSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0005-2736Keywords: Computer simulation ; Lipid bilayer ; Membrane dynamics ; Monte Carlo methodSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
13Patel, U.A. ; Bandiera, A. ; Manfioletti, G. ; Giancotti, V. ; Chau, K.Y. ; Cranerobinson, C.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Wratten, M.L. ; van't Veld, A.A. ; van der Heide, U.A. ; van Ginkel, G. ; Sevanian, A. ; Levine, Y.K.
Amsterdam : ElsevierStaff ViewISSN: 0891-5849Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
16Nilsson, U.A. ; Olsson, L.-I. ; Thor, H. ; Moldeus, P. ; Bylund-Fellenius, A.-C.
Amsterdam : ElsevierStaff ViewISSN: 0891-5849Keywords: ESR ; Ischemia and reperfusion ; Nitroxyl radicals ; Small intestine ; Spin trapping ; Superoxide ; Superoxide dismutaseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0003-2670Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0003-2670Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0020-1693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0003-2697Keywords: HPLC ; bufuralol ; cytochrome P-450 ; debrisoquine, dextromethorphan ; drug metabolism ; human liverSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: