Search Results - (Author, Cooperation:Z. Shang)
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1L. H. Fraser ; J. Pither ; A. Jentsch ; M. Sternberg ; M. Zobel ; D. Askarizadeh ; S. Bartha ; C. Beierkuhnlein ; J. A. Bennett ; A. Bittel ; B. Boldgiv ; Boldrini, II ; E. Bork ; L. Brown ; M. Cabido ; J. Cahill ; C. N. Carlyle ; G. Campetella ; S. Chelli ; O. Cohen ; A. M. Csergo ; S. Diaz ; L. Enrico ; D. Ensing ; A. Fidelis ; J. D. Fridley ; B. Foster ; H. Garris ; J. R. Goheen ; H. A. Henry ; M. Hohn ; M. H. Jouri ; J. Klironomos ; K. Koorem ; R. Lawrence-Lodge ; R. Long ; P. Manning ; R. Mitchell ; M. Moora ; S. C. Muller ; C. Nabinger ; K. Naseri ; G. E. Overbeck ; T. M. Palmer ; S. Parsons ; M. Pesek ; V. D. Pillar ; R. M. Pringle ; K. Roccaforte ; A. Schmidt ; Z. Shang ; R. Stahlmann ; G. C. Stotz ; S. Sugiyama ; S. Szentes ; D. Thompson ; R. Tungalag ; S. Undrakhbold ; M. van Rooyen ; C. Wellstein ; J. B. Wilson ; T. Zupo
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-07-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Biodiversity ; Biomass ; *Grassland ; *Plant Development ; Stress, PhysiologicalPublished by: -
2Staff View
Publication Date: 2018-03-06Publisher: Oxford University PressPrint ISSN: 0305-1048Electronic ISSN: 1362-4962Topics: BiologyPublished by: -
3N. Barbero, S. Holenstein, T. Shang, Z. Shermadini, F. Lochner, I. Eremin, C. Wang, G.-H. Cao, R. Khasanov, H.-R. Ott, J. Mesot, and T. Shiroka
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-04-14Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Superfluidity and superconductivityPublished by: -
4Staff View
Publication Date: 2018-03-06Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Cardiovascular medicinePublished by: -
5L. M. Tran, M. Babij, L. Korosec, T. Shang, Z. Bukowski, and T. Shiroka
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-09-12Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: MagnetismPublished by: -
6Gozal, Evelyne ; Gozal, David ; Pierce, William M. ; Thongboonkerd, Visith ; Scherzer, Janice A. ; R. Sachleben, Leroy ; Brittian, Kenneth R. ; Guo, Shang-Z. ; Cai, Jian ; Klein, Jon B.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The CA1 and CA3 regions of the hippocampus markedly differ in their susceptibility to hypoxia in general, and more particularly to the intermittent hypoxia that characterizes sleep apnea. Proteomic approaches were used to identify proteins differentially expressed in the CA1 and CA3 regions of the rat hippocampus and to assess changes in protein expression following a 6-h exposure to intermittent hypoxia (IH). Ninety-nine proteins were identified, and 15 were differentially expressed in the CA1 and the CA3 regions. Following IH, 32 proteins in the CA1 region and only 7 proteins in the more resistant CA3 area were up-regulated. Hypoxia-regulated proteins in the CA1 region included structural proteins, proteins related to apoptosis, primarily chaperone proteins, and proteins involved in cellular metabolic pathways. We conclude that IH-mediated CA1 injury results from complex interactions between pathways involving increased metabolism, induction of stress-induced proteins and apoptosis, and, ultimately, disruption of structural proteins and cell integrity. These findings provide initial insights into mechanisms underlying differences in susceptibility to hypoxia in neural tissue, and may allow for future delineation of interventional strategies aiming to enhance neuronal adaptation to IH.Type of Medium: Electronic ResourceURL: -
7Gozal, David ; Row, Barry W. ; Kheirandish, Leila ; Liu, Rugao ; Guo, Shang Z. ; Qiang, Fan ; Brittian, Kenneth R.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Obstructive sleep apnea (OSA) is a frequent medical condition characterized by intermittent hypoxia (IH) during sleep, and is associated with neurodegenerative changes in several brain regions along with learning deficits. We hypothesized that aging rats exposed to IH during sleep would be particularly susceptible. Young (3–4 months) and aging (20–22 months) Sprague–Dawley rats were therefore exposed to either room air or IH for 14 days. Learning and memory was assessed with a standard place-training version of the Morris water maze. Aging rats exposed to room air (RA) or IH displayed significant spatial learning impairments compared with similarly exposed young rats; furthermore, the decrements in performance between RA and IH were markedly greater in aging compared with young rats (p 〈 0.01), and coincided with the magnitude of IH-induced decreases in cyclic AMP response element binding (CREB) phosphorylation. Furthermore, decreases in proteasomal activity occurred in both young and aging rats exposed to IH, but were substantially greater in the latter (p 〈 0.001). Neuronal apoptosis, as shown by cleaved caspase 3 expression, was particularly increased in aging rats exposed to IH (p 〈 0.01 versus young rats exposed to IH). Collectively, these findings indicate unique vulnerability of the aging rodent brain to IH, which is reflected at least in part, by the more prominent decreases in CREB phosphorylation and a marked inability of the ubiquitin-proteasomal pathway to adequately clear degraded proteins.Type of Medium: Electronic ResourceURL: -
8Row, Barry W. ; Kheirandish, Leila ; Li, Richard C. ; Guo, Shang Z. ; Brittian, Kenneth R. ; Hardy, Mattie ; Bazan, Nicolas G. ; Gozal, David
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Intermittent hypoxia (IH) during sleep, a hallmark of sleep apnea, is associated with neurobehavioral impairments, regional neurodegeneration and increased oxidative stress and inflammation in rodents. Platelet-activating factor (PAF) is an important mediator of both normal neural plasticity and brain injury. We report that mice deficient in the cell surface receptor for PAF (PAFR–/–), a bioactive mediator of oxidative stress and inflammation, are protected from the spatial reference learning deficits associated with IH. Furthermore, PAFR–/– exhibit attenuated elevations in inflammatory signaling (cyclo-oxygenase-2 and inducible nitric oxide synthase activities), degradation of the ubiquitin–proteasome pathway and apoptosis observed in wild-type littermates (PAFR+/+) exposed to IH. Collectively, these findings indicate that inflammatory signaling and neurobehavioral impairments induced by IH are mediated through PAF receptors.Type of Medium: Electronic ResourceURL: -
9Gozal, David ; Row, Barry W. ; Gozal, Evelyne ; Kheirandish, Leila ; Neville, Jennifer J. ; Brittian, Kenneth R. ; Sachleben, Leroy R. ; Guo, Shang Z.
Oxford, UK : Blackwell Science, Ltd
Published 2003Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Intermittent hypoxia (IH) during sleep, such as occurs in obstructive sleep apnea, leads to degenerative changes in the hippocampus, and is associated with spatial learning deficits in the adult rat. We report that in Sprague–Dawley rats the initial IH-induced impairments in spatial learning are followed by a partial functional recovery over time, despite continuing IH exposure. These functional changes coincide with initial decreases in basal neurogenesis as shown by the number of positively colabelled cells for BrdU and neurofilament in the dentate gyrus of the hippocampus, and are followed by increased expression of neuronal progenitors and mature neurons (nestin and BrdU-neurofilament positively labelled cells, respectively). In contrast, no changes occurred during the course of IH exposures in the expression of the synaptic proteins synaptophysin, SNAP25, and drebrin. Collectively, these findings indicate that the occurrence of IH during the lights on period results in a biphasic pattern of neurogenesis in the hippocampus of adult rats, and may account for the observed partial recovery of spatial function.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0003-2697Keywords: 7 S particle ; ammonium sulfate precipitation ; transcription factor IIIASource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0968-0004Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0146-5724Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
14Dhert, Ph. ; Schoeters, K. ; Vermeulen, P. ; Sun, J. ; Gao, S. ; Shang, Z. ; Naihong, X. ; Van Duffel, H. ; Sorgeloos, P.
Springer
Published 1997Staff ViewISSN: 1573-143XKeywords: Brachionus plicatilis ; Disinfection ; Resting egg production ; RotifersSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract The dynamics of resting egg production of the rotifer Brachionus plicatilis originating from a wild population in the Tanggu Saltworks (P.R. China) was investigated. In the natural environment as well as in semi-controlled rearing conditions an increased resting egg production was noticed with declining food availability. Processed resting eggs had a hatching efficiency of 3 x 10 6 rotifers per gramme irrespective of their origin. Hatching started 22 h after the initiation of incubation and was completed after 36 h. Rotifers obtained from resting eggs could be further cultured on Culture Selco® and enriched with Super Selco®. The fatty acid profile of these rotifers were not divergent from reference rotifers (originating from the Laboratory of Aquaculture and Artemia Reference Centre) demonstrating that this strain was not catabolizing essential fatty acids and could be used for enrichment purposes. Storage of resting eggs at 4°C resulted in a 50% lower hatching after 1 year but remained stable during the next 2 years. The resting eggs used for storage could easily be disinfected without affecting their hatching characteristics. These results indicate that this material could be used as inocula for mass cultures of live food for commercial hatcheries.Type of Medium: Electronic ResourceURL: