Search Results - (Author, Cooperation:Z. L. Hu)

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  1. 1
    M. A. Groenen ; A. L. Archibald ; H. Uenishi ; C. K. Tuggle ; Y. Takeuchi ; M. F. Rothschild ; C. Rogel-Gaillard ; C. Park ; D. Milan ; H. J. Megens ; S. Li ; D. M. Larkin ; H. Kim ; L. A. Frantz ; M. Caccamo ; H. Ahn ; B. L. Aken ; A. Anselmo ; C. Anthon ; L. Auvil ; B. Badaoui ; C. W. Beattie ; C. Bendixen ; D. Berman ; F. Blecha ; J. Blomberg ; L. Bolund ; M. Bosse ; S. Botti ; Z. Bujie ; M. Bystrom ; B. Capitanu ; D. Carvalho-Silva ; P. Chardon ; C. Chen ; R. Cheng ; S. H. Choi ; W. Chow ; R. C. Clark ; C. Clee ; R. P. Crooijmans ; H. D. Dawson ; P. Dehais ; F. De Sapio ; B. Dibbits ; N. Drou ; Z. Q. Du ; K. Eversole ; J. Fadista ; S. Fairley ; T. Faraut ; G. J. Faulkner ; K. E. Fowler ; M. Fredholm ; E. Fritz ; J. G. Gilbert ; E. Giuffra ; J. Gorodkin ; D. K. Griffin ; J. L. Harrow ; A. Hayward ; K. Howe ; Z. L. Hu ; S. J. Humphray ; T. Hunt ; H. Hornshoj ; J. T. Jeon ; P. Jern ; M. Jones ; J. Jurka ; H. Kanamori ; R. Kapetanovic ; J. Kim ; J. H. Kim ; K. W. Kim ; T. H. Kim ; G. Larson ; K. Lee ; K. T. Lee ; R. Leggett ; H. A. Lewin ; Y. Li ; W. Liu ; J. E. Loveland ; Y. Lu ; J. K. Lunney ; J. Ma ; O. Madsen ; K. Mann ; L. Matthews ; S. McLaren ; T. Morozumi ; M. P. Murtaugh ; J. Narayan ; D. T. Nguyen ; P. Ni ; S. J. Oh ; S. Onteru ; F. Panitz ; E. W. Park ; H. S. Park ; G. Pascal ; Y. Paudel ; M. Perez-Enciso ; R. Ramirez-Gonzalez ; J. M. Reecy ; S. Rodriguez-Zas ; G. A. Rohrer ; L. Rund ; Y. Sang ; K. Schachtschneider ; J. G. Schraiber ; J. Schwartz ; L. Scobie ; C. Scott ; S. Searle ; B. Servin ; B. R. Southey ; G. Sperber ; P. Stadler ; J. V. Sweedler ; H. Tafer ; B. Thomsen ; R. Wali ; J. Wang ; S. White ; X. Xu ; M. Yerle ; G. Zhang ; J. Zhang ; S. Zhao ; J. Rogers ; C. Churcher ; L. B. Schook
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-11-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Demography ; Genome/*genetics ; Models, Animal ; Molecular Sequence Data ; *Phylogeny ; Population Dynamics ; Sus scrofa/*classification/*genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Zhang, X. F. ; Mosjidis, J. A. ; Hu, Z. L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1992
    Staff View
    ISSN:
    1439-0523
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Several methods have been proposed over the years to detect linkage between a marker gene and quantitative trait locus (QTL). Use of isozymes and restriction fragment length polymorphisms as genetic markers, has encouraged the development of new methods to detect linkage. We present three methods to detect linkage and two methods to measure recombination frequency (r). The three methods that detect linkage can be used when a single QTL or a tightly linked cluster of QTLs control the quantitative trait. The two methods that measure recombination frequency could not be used in the latter case because r would not be properly estimated. Procedures to calculate the additive and dominance gene effects of the QTL and the respective variances of these estimates were also presented.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1439-0523.1992.tb00147.x

    Articles: DFG German National Licenses
  3. 3
    Wang, Q.-M. ; Sun, S.-H. ; Hu, Z.-L. ; Zhou, F.-J. ; Yin, M. ; Xiao, C.-J. ; Zhang, J.-C.

    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we constructed epitope DNA vaccines (p3-M-38) encoding cytotoxic T lymphocyte (CTL) epitopes of MPT64 and 38 kDa proteins of Mycobacterium tuberculosis. In order to observe the influence of spacer sequence (Ala-Ala-Tyr) or ubiquitin (UbGR) on the efficacy of the two CTL epitopes, we also constructed DNA vaccines, p3-M-S(spacer)-38, p3-Ub (UbGR)-M-S-38 and p3-Ub-M-38. The immune responses elicited by the four DNA vaccines were tested in C57BL/6 (H-2b) mice. The cytotoxicity of T cells was detected by LDH-release method and by enzyme-linked immunospot assay for epitope-specific cells secreting interferon-γ. The results showed that DNA immunization with p3-M-38 vaccine could induce epitope-specific CD8+ CTL response and that the spacer sequence (AAY) only enhanced M epitope presentation. The protein-targeting sequence (UbGR) enhanced the immunogenicity of the two epitopes. The finding that defined spacer sequences at C-terminus and protein-targeting degradation modulated the immune response of epitope string DNA vaccines will be of importance for the further development of multi-epitope DNA vaccines against tuberculosis.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.0300-9475.2004.01442.x

    Articles: DFG German National Licenses
  4. 4
    Hu, Z.-L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-2166
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Linguistics and Literary Studies
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-2166(84)90001-8

    Articles: DFG German National Licenses