Search Results - (Author, Cooperation:Y. Yoshikuni)

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  1. 1
    A. J. Wargacki ; E. Leonard ; M. N. Win ; D. D. Regitsky ; C. N. Santos ; P. B. Kim ; S. R. Cooper ; R. M. Raisner ; A. Herman ; A. B. Sivitz ; A. Lakshmanaswamy ; Y. Kashiyama ; D. Baker ; Y. Yoshikuni
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-01-24
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alginates/chemistry/*metabolism ; Bacterial Proteins/genetics/metabolism ; *Biofuels ; Biological Transport ; Biomass ; Carrier Proteins/genetics/metabolism ; Escherichia coli/*genetics/metabolism ; Ethanol/*metabolism ; Fermentation ; Genes, Bacterial ; Glucose/metabolism ; Glucuronic Acid/chemistry/metabolism ; Hexuronic Acids/chemistry/metabolism ; Lactic Acid/metabolism ; Mannitol/metabolism ; *Metabolic Engineering ; Metabolic Networks and Pathways ; Open Reading Frames ; Phaeophyta/*metabolism ; Polysaccharide-Lyases/genetics/metabolism ; Seaweed/*metabolism ; Vibrio/*enzymology/genetics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2013-12-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alginates/metabolism ; Anaerobiosis ; Ascomycota/genetics/metabolism ; Biofuels/*supply & distribution ; Biotechnology ; *Carbohydrate Metabolism ; Carrier Proteins/genetics/metabolism ; Ethanol/*metabolism ; Evolution, Molecular ; Fermentation ; Genetic Complementation Test ; *Genetic Engineering ; Glucuronic Acid/metabolism ; Hexuronic Acids/metabolism ; Mannitol/metabolism ; Phaeophyta/genetics/*metabolism ; Quinic Acid/metabolism ; Reproducibility of Results ; Saccharomyces cerevisiae/genetics/*metabolism ; Seaweed/genetics/metabolism ; Uronic Acids/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Tatsumi, S. ; Itoh, Y. ; Ma, F.-H. ; Higashira, H. ; Ukai, Y. ; Yoshikuni, Y. ; Kimura, K.

    Oxford, UK : Blackwell Science Ltd
    Published 1998
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: Neuronal nitric oxide synthase (NOS) is considered to be involved in the pathogenesis of ischemic brain damage. In the present study, the effect of a novel neuroprotective phenylpyrimidine derivative, 4-(4-fluorophenyl)-2-methyl-6-(5-piperidinopentyloxy)pyrimidine hydrochloride (NS-7), on depolarization-stimulated NOS activity was examined in cultured neurons of mouse cerebral cortex. Various depolarizing stimuli such as veratridine, KCl, and N-methyl-d-aspartate increased the NOS activity determined by cyclic GMP formation. NS-7 concentration-dependently inhibited both the veratridine- and KCl-induced NOS activation with IC50 values of 9.3 and 9.6 µM, respectively. The reversal of KCl-evoked NOS activity by NS-7 was also observed under blockade of both ionotropic glutamate receptors and the Na+ channel with MK-801, 6-cyano-7-nitroquinoxaline-2,3-dione, and tetrodotoxin. In contrast, NS-7, even at 100 µM, did not affect N-methyl-d-aspartate-stimulated NOS activity, nor did it have any influence on NOS activity determined in the soluble fraction of rat hippocampus. Because NS-7 has already been shown to block both Na+ and Ca2+ channels, the present findings suggest that this compound inhibits depolarization-induced NOS activation by reducing Ca2+ influx through blockade of Na+ and Ca2+ channels in primary neuronal culture.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.1998.70010059.x

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0925-4439
    Keywords:
    (Hep-G2 cell) ; Antithrombin ; Serine proteinase ; α2-Plasmin inhibitor
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0925-4439(94)90041-8

    Articles: DFG German National Licenses
  5. 5
    Wakita, K. ; Kawamura, Y. ; Yoshikuni, Y. ; Asahi, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0039-6028
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0039-6028(86)90413-9

    Articles: DFG German National Licenses
  6. 6
    Yoshikuni, Y. ; Saito, H. ; Shionoya, S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0038-1098
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0038-1098(79)90723-3

    Articles: DFG German National Licenses
  7. 7
    Wakita, K. ; Kawamura, Y. ; Yoshikuni, Y. ; Asahi, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-2584
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-2584(86)90040-X

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0030-4018
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0030-4018(83)90232-8

    Articles: DFG German National Licenses