Search Results - (Author, Cooperation:Y. Umesono)
-
1Y. Umesono ; J. Tasaki ; Y. Nishimura ; M. Hrouda ; E. Kawaguchi ; S. Yazawa ; O. Nishimura ; K. Hosoda ; T. Inoue ; K. Agata
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-07-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Body Patterning/drug effects/*physiology ; Cell Differentiation ; Down-Regulation ; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors/metabolism ; Feedback, Physiological ; Head/physiology ; Logic ; MAP Kinase Signaling System/drug effects ; Phenotype ; Planarians/*anatomy & histology/drug effects/*physiology ; Receptors, Fibroblast Growth Factor/chemistry/metabolism ; Regeneration/drug effects/*physiology ; Stem Cells/cytology/metabolism ; Wnt Proteins/metabolism ; Wnt Signaling Pathway ; beta Catenin/deficiency/genetics/metabolismPublished by: -
2Staff View
ISSN: 0965-1748Keywords: Athalia rosae ; Hymenoptera ; N-terminal amino acid sequence ; Nucleotide sequence ; Signal peptide sequence ; Vitellogenin cDNASource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 1432-041XKeywords: Key words Homeobox gene ; Brain ; otd/Otx ; otp ; PlanarianSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Homeobox genes such as orthodenticle in Drosophila and its mouse homologues, Otx1 and Otx2, are known to be essential for rostral brain development. To investigate the molecular basis of brain evolution, we searched for otd/Otx-related homeobox genes in the planarian Dugesia japonica, and identified two genes, DjotxA and B, whose expression appears to be restricted to the cephalic ganglion (brain). DjotxA was expressed more medially, in the region containing the termini of the visual axons, and in the visual cells, suggesting involvement in establishment of the visual system. DjotxB was expressed in a discrete region just lateral to the DjotxA-positive domain, but not in the more lateral branch structures, which in turn are characterized by the expression of Djotp, a planarian homeobox gene related to mouse Orthopedia (Otp). In transverse sections of planarians, DjotxA and B expression were observed only at the anterior ends of the stumps, corresponding to the regional pattern of the regenerating brain. Our findings suggest that the planarian brain is composed of structurally distinct and functionally diverse domains which are defined by the discrete expression of the three evolutionarily conserved homeobox genes.Type of Medium: Electronic ResourceURL: