Search Results - (Author, Cooperation:Y. Umesono)

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  1. 1
    Y. Umesono ; J. Tasaki ; Y. Nishimura ; M. Hrouda ; E. Kawaguchi ; S. Yazawa ; O. Nishimura ; K. Hosoda ; T. Inoue ; K. Agata
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-07-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Body Patterning/drug effects/*physiology ; Cell Differentiation ; Down-Regulation ; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors/metabolism ; Feedback, Physiological ; Head/physiology ; Logic ; MAP Kinase Signaling System/drug effects ; Phenotype ; Planarians/*anatomy & histology/drug effects/*physiology ; Receptors, Fibroblast Growth Factor/chemistry/metabolism ; Regeneration/drug effects/*physiology ; Stem Cells/cytology/metabolism ; Wnt Proteins/metabolism ; Wnt Signaling Pathway ; beta Catenin/deficiency/genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    0965-1748
    Keywords:
    Athalia rosae ; Hymenoptera ; N-terminal amino acid sequence ; Nucleotide sequence ; Signal peptide sequence ; Vitellogenin cDNA
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
    Umesono, Y. ; Watanabe, Kenji ; Agata, K.
    Springer
    Published 1999
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    ISSN:
    1432-041X
    Keywords:
    Key words Homeobox gene ; Brain ; otd/Otx ; otp ; Planarian
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract  Homeobox genes such as orthodenticle in Drosophila and its mouse homologues, Otx1 and Otx2, are known to be essential for rostral brain development. To investigate the molecular basis of brain evolution, we searched for otd/Otx-related homeobox genes in the planarian Dugesia japonica, and identified two genes, DjotxA and B, whose expression appears to be restricted to the cephalic ganglion (brain). DjotxA was expressed more medially, in the region containing the termini of the visual axons, and in the visual cells, suggesting involvement in establishment of the visual system. DjotxB was expressed in a discrete region just lateral to the DjotxA-positive domain, but not in the more lateral branch structures, which in turn are characterized by the expression of Djotp, a planarian homeobox gene related to mouse Orthopedia (Otp). In transverse sections of planarians, DjotxA and B expression were observed only at the anterior ends of the stumps, corresponding to the regional pattern of the regenerating brain. Our findings suggest that the planarian brain is composed of structurally distinct and functionally diverse domains which are defined by the discrete expression of the three evolutionarily conserved homeobox genes.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses