Search Results - (Author, Cooperation:Y. Sugita)

Showing 1 - 20 results of 94, query time: 0.27s Refine Results
  1. 1
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2013-07-12
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antiviral Agents/pharmacology ; Cells, Cultured ; Chickens/virology ; DNA-Directed RNA Polymerases/antagonists & inhibitors ; Dogs ; Enzyme Inhibitors/pharmacology ; Female ; Ferrets/virology ; Humans ; Influenza A Virus, H1N1 Subtype/drug effects/enzymology ; *Influenza A virus/chemistry/drug effects/isolation & purification/pathogenicity ; Influenza, Human/drug therapy/*virology ; Macaca fascicularis/virology ; Madin Darby Canine Kidney Cells ; Male ; Mice ; Mice, Inbred BALB C ; Models, Molecular ; Monkey Diseases/pathology/virology ; Neuraminidase/antagonists & inhibitors ; Orthomyxoviridae Infections/pathology/transmission/*virology ; Quail/virology ; Swine/virology ; Swine, Miniature/virology ; *Virus Replication/drug effects
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-04-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Arginine/metabolism ; Bacillus/*chemistry ; Bacterial Proteins/*chemistry/*metabolism ; Cell Membrane/chemistry/*metabolism ; Conserved Sequence ; Crystallography, X-Ray ; Hydrophobic and Hydrophilic Interactions ; Membrane Transport Proteins/*chemistry/*metabolism ; Molecular Chaperones/chemistry/metabolism ; Protein Folding ; Static Electricity ; Structure-Activity Relationship
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Takahashi, H. ; Mitsuoka, K. ; Komuro, M. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The g factor and 4π Ms for epitaxially grown Fe16N2(001)/In0.2Ga0.8As(001) films have been investigated by ferromagnetic resonance along with Fe films for comparison. Angular dependence of the resonance fields in the film plane of Fe16N2 films had four-fold symmetry, which was attributed to the in-plane anisotropy. The g factor for Fe16N2 films was about 2.0, which means that the magnetic moment originates mainly from spin. Thus, nothing unusual is seen about the g factor. The g factor for Fe films was about 2.1, which is very similar to the value reported previously. 4πMs values for Fe16N2 and Fe films were 2.8×104 and 2.1×104 G, respectively, which agree well with the previous data obtained by a vibrating sample magnetometer. This confirmed that Fe16N2 has a giant magnetic moment. Torque magnetometer measurements showed that Fe16N2 films have a larger perpendicular anisotropy of 7.8×106 erg/cm3, which can originate from its bct structure.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Tanabe, M. ; Fukui, H. ; Uesaka, Y. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1990
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A model of overwrite based on anisotropy field distributions of particles has been proposed for γFe2O3 and Co-γFe2O3 high-coercivity particulate media. In this model, overwrite is determined by the ratio of the number of nonreversed particles to the total number of particles. The magnitude and angle distributions of the anisotropy field were obtained by torque magnetometer measurements. From these observed distributions, switching field distributions of the particles were derived using the curling model for an infinite cylinder. The write field of thin-film heads was calculated using a finite element method. The nonreversal ratio in the medium was given by both the switching and the write fields. The calculated overwrite values were obtained from this ratio and were found to be in good agreement with the measured ones. This model was valid for the media which differed in the distributions of the anisotropy field. The overwrite performance can be improved by narrowing the anisotropy field distributions of the particles in the media.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Sugita, Y. ; Mitsuoka, K. ; Komuro, M. ; Hoshiya, H. ; Kozono, Y. ; Hanazono, M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1991
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Single-crystal Fe16N2 films have been grown epitaxially on Fe(001)/InGaAs(001) and InGaAs(001) substrates by molecular beam epitaxy (MBE). Saturation flux density Bs of Fe16N2 films has been demonstrated to be 2.8–3.0 T at room temperature, which is very close to the value obtained by Kim and Takahashi using polycrystalline evaporated Fe–N films. Temperature dependence of Bs has been measured. Bs changed with temperature reversibly up to 400 °C, while beyond 400 °C, Bs decreased irreversibly. X-ray diffraction showed that Fe16N2 crystal is stable up to 400 °C, while beyond 400 °C, Fe16N2 dissolves into Fe and Fe4N, and also some chemical reactions between Fe16N2 and the substrate occurs. This caused the temperature dependence of Bs mentioned above. From the temperature dependence of Bs up to 400 °C, the Curie temperature of Fe16N2 is estimated to be around 540 °C by using the Langevin function. The above mentioned Bs of 2.9 T at room temperature and 3.2 T at −268 °C corresponded to an average magnetic moment of 3.2μB per Fe atom and 3.5μB, respectively. These values of the magnetic moment of Fe atoms are literally giant, far beyond the Slater–Pauling curves. The origin of the giant magnetic moment has been discussed based on the calculation carried out by Sakuma. However, there was a significant disagreement between experimental values and calculated ones, so the origin remained to be clarified. Also, magneto-crystalline anisotropy of Fe16N2 films has been investigated.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Yajima, Y. ; Takahashi, Y. ; Takeshita, M. ; Kobayashi, T. ; Ichikawa, M. ; Hosoe, Y. ; Shiroishi, Y. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A transmission electron microscope operating with a cold field emission source has been modified to facilitate differential phase contrast mapping and applied to the observation of microscopic magnetic features appearing in recorded longitudinal media. After describing the design and performance of the scanning Lorentz electron microscope, as we call it, results on the observation of bit patterns delineated on Co-based sputtered longitudinal media are presented. Relations of observed bit profiles to macroscopic magnetic properties of media and to device performance are discussed. Then, magnetization fluctuation on a scale of magnetic crystallites constituting the medium is examined. Also given is an account of a stray field effect inherent in hard magnetic materials.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Shiroishi, Y. ; Hosoe, Y. ; Ishikawa, A. ; Yahisa, Y. ; Sugita, Y. ; Suzuki, H. ; Ohno, T. ; Ohura, M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A Cr-Ti underlayer is found to enhance the in-plane coercive forces of Co-Cr-Pt and Co-Cr-Ta films; the maximum coercive force was 3.5 kOe for (CoCr0.15)0.84Pt0.16/CrTi0.2. The crystallites of Cr-Ti grow in a more highly oriented and uniform manner than ones of Cr, and their lattice spacings are closer to those of Co alloys than Cr, improving the epitaxial growth of Co-alloy crystallites with c-axis in-plane oriented components on the Cr-Ti underlayer. The crystalline anisotropy constant of Co-Cr-Pt with a high Pt concentration is found by torque measurement to be larger than that of Co-Cr-Ta. These can produce extremely high coercive forces in Co-Cr-Pt/Cr-Ti. The C/Co-Cr-Pt/Cr-Ti thin film media with high coercive forces show excellent read/write characteristics; the linear densities at 50% signal drop are very high, 175 and 101 kFCI, for the C/Co-Cr-Pt/Cr-Ti media at head-to-magnetic layer spacings of 0.01 and 0.07 μm.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Imagawa, T. ; Mitsuoka, K. ; Narishige, S. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1990
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Thin film heads made of Co-based amorphous films with high saturation magnetization were reported to have superior capabilities for high-density magnetic recording.1 However, it was found that the uniaxial anisotropy is changed during head fabrication processes. In this study, we investigate the relaxation process of the uniaxial anisotropy of sputtered Co-Zr amorphous films. 1-μm-thick Co-Zr films of 1.4 T were prepared by rf sputtering. Uniaxial anisotropy was induced by the magnetic field of 50 Oe during deposition. After deposition, annealing was performed in the dc field of 500 Oe applied parallel to the easy axis of the films for stabilizing the uniaxial anisotropy (preannealing). The preannealing temperature was changed from 200 to 350 °C. The films were annealed again in a field along the hard axis to reduce the uniaxial anisotropy. Decrease of the anisotropy field was discussed based on Richter-type relaxation,2 where τ2 is the maximum and τ1 is the minimum relaxation time, respectively. Without preannealing, the bandwidth ln(τ2/τ1) is broad at higher annealing temperatures. With preannealing, the bandwidth becomes narrower and is almost constant for various preannealing temperatures. These results show that the relaxation processes with shorter relaxation times are all suppressed by preannealing. The average activation energy is 2.0 eV without preannealing. It increases with preannealing temperatures and reaches 2.9 eV at 350 °C. From these results, it is clear that preannealing at higher temperatures is more effective in stabilizing the uniaxial anisotropy in the CoZr amorphous films.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Shimatsu, T. ; Komagome, H. ; Watanabe, I. ; Muraoka, H. ; Sugita, Y. ; Nakamura, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The effect of a Ti seed layer on the magnetic properties and microstructure of Co77Cr19Ta4 was studied in Co77Cr19Ta4/Ti/M (M=Co91Zr3Nb6, Fe, Co) double-layered perpendicular recording media. A thin Ti film of ∼5 nm enhanced the c-axis alignment perpendicular to the film plane, resulting in a large perpendicular anisotropy Ku and the best magnetic properties under the present experimental conditions. The coercivity at this Ti thickness (3–3.7 kOe) was approximately half of the magnetocrystalline anisotropy field Hk estimated from the Ku value, even with the present thick 50 nm CoCrTa. The recording performance using a single-pole-type writing head showed that media with a 5 nm Ti layer had higher recording sensitivity compared to media without Ti layers, and a higher SN value at densities greater than 200 kFRPI. No significant loss of recording resolution due to the nonmagnetic Ti space between the CoCrTa and the back layers was observed by the use of the 5 nm Ti film. Moreover, the results for media with Fe back layers indicated that a thinner back layer with a high flux density can be used without any reduction of recording sensitivity and resolution. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Greaves, S. J. ; Muraoka, H. ; Sugita, Y. ; Nakamura, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Simulations of perpendicular recording media were carried out to determine the effect of switching speed limitations upon recording performance. Simulations of hysteresis loops at various applied field sweep rates show that the onset of a switching speed limited increase in coercivity occurs for sweep rates in excess of 2×1013 Oe/s. Switching speeds of individual grains were found to be around 18 to 38 ps, depending on the medium thickness and the magnetization state of surrounding grains. Recording simulations show that for media thicknesses of up to 180 Å, writing frequencies of 5 Gbit/s are feasible before loss of output occurs. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Ishii, N. ; Onoda, M. ; Sugita, Y.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Sugita, Y. ; Ishii, N. ; Katsuno, M. ; Yamada, R. ; Nakajima, H.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    We describe familial cases of cutaneous infection caused by Mycobacterium avium. A 45-year-old father, his 14-year-old son and 11-year-old daughter, among five persons in a family, presented with a 2-month history of inflammatory subcutaneous nodules and ulcerations. Histology of skin biopsy specimens showed granulomatous inflammation, and mycobacterial colonies isolated from the skin of each patient were identified as M. avium by DNA hybridization analysis. The patients were all treated successfully with combined drug therapy consisting of rifampicin, isoniazid and clarithromycin. Their lesions were purely cutaneous M. avium infection, without any visceral involvement. Neither systemic disease nor immunological impairment was detected in the family. However, they all used a circulating, constantly heated bath water system. The bath water was continuously heated to about 40 °C without changing the water for a few months, and M. avium was isolated from the filter of the bath tub heating unit. It is considered that this unusual familial cluster of cutaneous M. avium infection in healthy persons may have resulted from the use of contaminated bath water.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    SUGITA, Y. ; MIYAMOTO, M. ; KOSEKI, M. ; ISHII, N. ; NAKAJIMA, H.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1997
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The expression of tumour necrosis factor (TNF)-α in leprosy skin lesions was examined before and during successful treatment in a patient with borderline lepromatous leprosy. Before treatment, immunohistochemical staining of a skin biopsy specimen showed diffuse TNF-α deposits in granulomas and significant TNF-α deposits on infiltrated mononuclear cells. After 1 year's treatment, the skin lesions exhibited a reduction in granulomas, and a concomitant reduction in deposits of TNF-α.Furthermore, the level of expression of TNF-α messenger RNA. as examined using a reverse transcriptase-polymerase chain reaction method, was reduced markedly after treatment. These findings provide evidence for a correlation between the expression of TNF-α and disease activity suggesting that TNF-α is a useful prognostic indicator for inflammation in leprosy.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Yoshida, K. ; Hara, M. ; Hirayama, Y. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The possibility of ultrahigh-density recording higher than 10 Gb/in.2 with perpendicular magnetic recording is investigated by computer simulation for a ring-type head and single-layer medium combination. A nucleation model is used as a media model because it incorporates a nucleation site, which causes irreversible magnetization switching. Fundamental read–write characteristics are found to be entirely different from those of longitudinal recording. Recorded magnetization strongly depends on head field strength; the maximum magnetization appears around the head field strength of media coercivity, and beyond this the recorded magnetization decreases abruptly. Spacing loss in the recording process also depends on head field strength and recording density. However, saturation recording can be attained even at an ultrahigh recording density of 600 kFCI with a spacing of 30 nm. Also, a higher signal-to-noise ratio than in longitudinal recording can be obtained by introducing weak intergrain exchange interaction with a relatively large grain size in the media film. This suggests that perpendicular magnetic recording is stable in thermal fluctuation. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Yajima, Y. ; Takahashi, Y. ; Kuroda, K. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We have implemented interference imaging mode as well as Lorentz imaging mode on a scanning transmission electron microscope (HITACHI HF-2000 with a scanning option; 200 kV accelerating voltage). In the interference mode, a pair of mutually coherent fine probes scan simultaneously across the region of magnetic induction. By monitoring the relative phase change occurring in the probe pair, the variation of the magnetic flux bound by the probe trajectories can be sensed by the universal unit of e/h (−||e||: electron charge and h: Planck's constant). The combined use of this imaging mode with the Lorentz mode which is based on the detection of the probe deflection by Lorentz force facilitates detailed analyses of fringing field around magnetic materials and magnetic induction inside magnetic films. The microscope described above is particularly suited for the study of magnetic storage devices whose microscopic magnetic properties are drawing much attention recently. We show here the results of its application to the observation of field distributions near the MR (magnetoresistive) heads and induction distributions associated with high density longitudinal and perpendicular recording media. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Nakajima, A. ; Sugita, Y. ; Kawamura, K. ; Tomita, H. ; Yokoyama, N.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We report a simple technique for fabricating a layer of isolated Si quantum dots on SiO2 glass substrates. This technique uses conventional low-pressure chemical-vapor deposition for an extremely short deposition time in the early stage of poly-Si film growth. The layer after a deposition time of 60 s has isolated Si nanocrystals 5–20 nm in diameter and 2–10 nm in height. The measurements of optical absorption coefficient α show that the absorption edge for Si nanocrystals shifts to higher energies compared to that of bulk Si, indicating a widening of the energy gap caused by quantum size effects. The linear relationship (αhν)1/2 against hν suggests that the Si nanocrystal, whose diameter is as small as 10 nm, basically maintains the properties of an indirect band-gap semiconductor. Special attention must be paid to the Brownian migration of Si nanocrystals for fabricating Si quantum dots. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Tomiyama, F. ; Takano, H. ; Shiroishi, Y. ; Suzuki, M. ; Sugita, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    High-frequency recording is essential for a recording channel with both a high data rate and a high linear recording density, and this study examined the ways in which performances are affected by the switching time of the write current, ts, and the disk velocity, v. The switching time, defined as (tr+tf)/2, where tr and tf are the rise time and the fall time of the write current, was changed from 5 to 20 ns, while v was changed from 12 to 26 m/s. Co-based thin-film media with a coercivity of about 2.5 kOe and a remanence-thickness product of about 100 G μm were used for recording the data. The flying height of the head was maintained at 50 nm regardless of disk velocity. This study confirmed that the overwrite characteristics are strongly related to the product of ts and v. Overwrite here was defined as the ratio of the residual fundamental frequency component amplitude of a 21 kFCI signal to the original one after overwriting with a 86 kFCI signal. Suitable overwrite characteristics were obtained when t*sv was smaller than πa, where a is the transition parameter derived from the equation proposed by Williams and Comstock. The transition length on the medium was determined primarily by πa when t*sv was smaller than πa, but was determined by t*sv when t*sv was larger than πa. Linear density characteristics and noise characteristics and their relationship to the medium properties will also be addressed in this talk. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Hanazono, M. ; Narishige, S. ; Hara, S. ; Mitsuoka, K. ; Kawakami, K. ; Sugita, Y. ; Kuwatsuka, S. ; Kobayashi, T. ; Ohura, M. ; Tsuji, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1987
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    High performance thin-film heads for disk drive systems have been developed based on a dry process. Heads were computer simulated and optimal design was carried out. Relationships among Ni-Fe composition, domain structure and wiggle of the read-write waveform were obtained. Based on these results, optimum Ni-Fe composition range was determined. A planarization procedure for an inbedding insulator of the conductor coil was developed. Also narrow track patterning and gap depth controlling procedures were developed. Using these procedures, a two-layered seventeen-turn thin-film head for a large capacity disk drive system (23 Mb/in.2) has been developed. The head exhibited excellent read-write characteristics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Imura, R. ; Sugita, Y. ; Suzuki, R.

    [S.l.] : American Institute of Physics (AIP)
    Published 1987
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Effect of the growth-induced anisotropy field HKG has been investigated for the anomalous increase of the effective anisotropy field change Δ(Hk−4πMs) caused by annealing in heavily ion-implanted magnetic bubble garnets. In heavily implanted garnets, Δ(Hk−4πMs) increases with decreasing strain during annealing and does not follow the same curve that is obtained during implantation. The maximum difference in Δ(Hk−4πMs) between annealed and as-implanted samples corresponds to the value of Δ(Hk−4πMs) when the strain is reduced to zero by annealing. The anomalous increase is small in HKG-suppressed samples and is not observed in garnet films (YIG) without HKG. It is considered that the anomalous increase is due to suppression of the growth-induced anisotropy by heavy implantation. However, in the case of H+2 implantation the increase of Δ(Hk−4πMs) during the annealing process cannot be explained by the HKG suppression effect.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses