Search Results - (Author, Cooperation:Y. Suehiro)

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  1. 1
    T. Okuyama ; S. Yokoi ; H. Abe ; Y. Isoe ; Y. Suehiro ; H. Imada ; M. Tanaka ; T. Kawasaki ; S. Yuba ; Y. Taniguchi ; Y. Kamei ; K. Okubo ; A. Shimada ; K. Naruse ; H. Takeda ; Y. Oka ; T. Kubo ; H. Takeuchi
    American Association for the Advancement of Science (AAAS)
    Published 2014
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    Publication Date:
    2014-01-05
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Female ; Gonadotropin-Releasing Hormone/*physiology ; Male ; *Mating Preference, Animal ; Mutation ; Neurons/*physiology ; Oryzias/genetics/*physiology ; Pyrrolidonecarboxylic Acid/*analogs & derivatives ; *Recognition (Psychology) ; Sex Factors ; *Visual Perception
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Liu, X P ; Kawauchi, S ; Oga, A ; Suehiro, Y ; Tsushimi, K ; Tsushimi, M ; Sasaki, K

    Oxford UK : Blackwell Science Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Combined examination of p27Kip1, p21Waf1/Cip1 and p53 expression allows precise estimation of prognosis in patients with gastric carcinoma Aims: In order to estimate the prognostic values of p27Kip1, p21Waf1/Cip1, and p53, alone and in combination, we investigated immunohistochemically the expression of p27Kip1, p21Waf1/Cip1, and p53 proteins in gastric carcinomas. Methods and results: The expression of p27Kip1, p21Waf1/Cip1, and p53 was immunohistochemically examined in 140 gastric carcinomas. Positive expression of p27Kip1 and p21Waf1/Cip1 correlated significantly with a favourable prognosis (P 〈 0.05), whereas, positive expression of p53 tended to correlate with poor prognosis. Multivariate survival analysis revealed that TNM stage of tumour (P 〈 0.001), lymph node state (P=0.005), and p27Kip1 expression (P=0.006) were independent prognostic factors. A striking stratification of mortality rate was found when patients were divided into four groups according to the expression of p21Waf1/Cip1 and p27Kip1. The mortality rate was higher in patients with both p21Waf1/Cip1- and p27Kip1-negative gastric carcinoma than in patients with one or both positive carcinomas (P 〈 0.01). In addition, if the four p21Waf1/Cip1/p27Kip1 groups were compared based on p53 status, p53+ cases tended to have a higher mortality rate than p53- cases. Conclusion: Our results suggest that low expression of both p27Kip1 and p21Waf1/Cip1 could be useful as markers of poorer prognosis, and the combined examination of p27Kip1, p21Waf1/Cip1 and p53 expression allows reliable estimation of prognosis for patients with gastric carcinoma.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2559.2001.01283.x

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)82832-7

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1433-0350
    Keywords:
    Key words Botulism ; Electrophysiology ; Blink reflex ; Children
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract  Electrophysiological studies of a child with presumed botulism showed that the amplitude of the serially and electrically elicited blink reflexes Rl, R2 and R2’ was reduced during recovery. These findings suggest a conduction block of the facial nerves. Other nerve conduction studies and an incremental response to repetitive stimulation demonstrated a block of the presynaptic neuromuscular transmission. Results of the biological tests were negative, but those of electrodiagnosis and clinical examination favored a diagnosis of botulism. A combination of electrically elicited blink reflexes and rapid repetitive stimulation of the peripheral nerves was found to be a sensitive method of assessing the integrity of neuromuscular junctions and the subclinical impairment of muscle nerves.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s003810050017

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1439-7609
    Keywords:
    Key words B lymphocytes ; Single-strand conformational polymorphism ; Sjögren's syndrome ; Immunoglobulin variable region
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract We encountered a patient with Sjögren's syndrome (SS) associated with bilateral parotid salivary gland swelling. Histological analysis of biopsy specimens from both parotid glands showed myoepithelial islands and infiltration of small- and intermediate-sized lymphocytes but no cytological atypia. Using reverse transcriptase-polymerase chain reaction and subsequent single-strand conformational polymorphism analysis, monoclonal B-cell expansion was detected in samples from both right and left parotid glands, bone marrow, and peripheral blood (PB). Our case suggests that the circulating clonal lymphocytes represent clones that can repopulate tissue sites and may contribute to B-cell lymphomagenesis. Detection of monoclonal B cells in PB is therefore considered to be important in monitoring the disease course of SS.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s101650070041

    Articles: DFG German National Licenses