Search Results - (Author, Cooperation:Y. Pommier)

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  1. 1
    N. Kim ; S. N. Huang ; J. S. Williams ; Y. C. Li ; A. B. Clark ; J. E. Cho ; T. A. Kunkel ; Y. Pommier ; S. Jinks-Robertson
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-06-28
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Transport Systems, Basic/genetics ; Base Sequence ; Camptothecin/pharmacology ; Canavanine/pharmacology ; DNA Breaks ; DNA Topoisomerases, Type I/*metabolism ; DNA, Fungal/chemistry/*metabolism ; DNA, Single-Stranded/metabolism ; Microsatellite Repeats ; Molecular Sequence Data ; *Mutagenesis ; Nucleic Acid Conformation ; Ribonuclease H/genetics/metabolism ; Ribonucleotides/*metabolism ; Saccharomyces cerevisiae/enzymology/*genetics/*metabolism ; Saccharomyces cerevisiae Proteins/genetics ; *Sequence Deletion ; Transcription, Genetic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Reinhold W, Pommier Y.
    Oxford University Press
    Published 2018
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    Oxford University Press
    Print ISSN:
    0923-7534
    Electronic ISSN:
    1569-8041
    Topics:
    Medicine
    Published by:
    http://global.oup.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Tang, S.-W., Thomas, A., Murai, J., Trepel, J. B., Bates, S. E., Rajapakse, V. N., Pommier, Y.
    The American Association for Cancer Research (AACR)
    Published 2018
    Staff View
    Publication Date:
    2018-04-14
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    1078-0432
    Electronic ISSN:
    1557-3265
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-12-04
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    1078-0432
    Electronic ISSN:
    1557-3265
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Leteurtre, F. ; Kohlhagen, G. ; Pommier, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/bbrc.1994.2318

    Articles: DFG German National Licenses
  6. 6
    Pommier, Y. ; Poddevin, B. ; Gupta, M. ; Jenkins, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/bbrc.1994.2850

    Articles: DFG German National Licenses
  7. 7
    Bertrand, R. ; Solary, E. ; Jenkins, J. ; Pommier, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-4827
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/excr.1993.1206

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0014-4827
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/excr.1994.1093

    Articles: DFG German National Licenses
  9. 9
    Solary, E. ; Bertrand, R. ; Jenkins, J. ; Pommier, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-4827
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0014-4827(92)90027-6

    Articles: DFG German National Licenses
  10. 10
    Zwelling, L.A. ; Kerrigan, D. ; Pommier, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-291X(82)91333-X

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-291X(82)91530-3

    Articles: DFG German National Licenses
  12. 12
    Pommier, Y. ; Runger, T.M. ; Kerrigan, D. ; Kraemer, K.H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0921-8777
    Keywords:
    Bloom-syndrome fibroblasts ; Bromodeoxyuridine ; DNA strand breakage ; Topoisomerase II
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-8777(91)90010-M

    Articles: DFG German National Licenses
  13. 13
    Andréjak, M. ; Pommier, Y. ; Mouillé, P. ; Schmitt, H.
    Springer
    Published 1980
    Staff View
    ISSN:
    1432-1912
    Keywords:
    Guinea-pig ileum ; Presynaptic α-adrenoceptors ; Clonidine ; Morphine ; α-Adrenoceptor blocking agents
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The purpose of the present study was to further characterize the α-adrenoceptors located on parasympathetic fibres. Segments of guinea-pig ileum were stimulated by transmural electrical pulses, and the ensuing contractions, which are due to the release of acetylcholine from postganglionic parasympathetic fibres, were monitored. Clonidine and tramazoline, which are thought to act preferentially on presynaptic α-adrenoceptors, reduced the contractions, whereas phenylephrine and methoxamine, postsynaptic α-adrenoceptor agonists, were ineffective. Contractions induced by acetylcholine were not changed by clonidine but were abolished by atropine. Yohimbine, piperoxan, phentolamine and thymoxamine reversed or prevented the inhibitory effect of clonidine. Prazosin and AR-C239 did not antagonize this effect. The inhibitory effect of tramazoline was antagonized by piperoxan but not by AR-C239 or by prazosin. Naloxone did not alter the action of clonidine, and piperoxan did not change the inhibitory effect of morphine. In conclusion, these experiments suggest the presence on cholinergic postganglionic fibres of both opiate receptors and α-adrenoceptors. The latter appear to resemble more closely α1-adrenoceptors than α1-adrenoceptors.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00498434

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    1432-1912
    Keywords:
    Mianserin ; Clonidine ; Desipramine ; Acetylcholine ; α2-Adrenoceptors
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The purpose of the present study was to characterize the effects of mianserin at α2-adrenoceptors. Firstly, the action of mianserin on postganglionic sympathetic fibres has been studied using the tachycardia induced by stimulation of the cardiac nerve in dogs. Mianserin increased this tachycardia, but could not prevent the inhibitory effect of clonidine in this model. However, an antagonistic effect of mianserin against clonidine was observed when animals were pretreated with desipramine. Secondly, mianserin antagonized the inhibitory effect of clonidine on the electrically stimulated guinea-pig ileum. In high concentrations, mianserin reduced both electrically and acetylcholine induced contractions. Thirdly, mianserin antagonised the sleep induced by clonidine in chickens. These results are consistent with α2-adrenoceptor blocking properties of mianserin in peripheral noradrenergic fibres in dogs, in cholinergic fibres in guinea-pig ileum and in the central nervous system in chickens.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00501167

    Articles: DFG German National Licenses
  15. 15
    Najean, Y. ; Pommier, Y. ; Deschryver, F. ; Chomienne, C.
    Springer
    Published 1986
    Staff View
    ISSN:
    1619-7089
    Keywords:
    111In Oxine ; Autologous ; Homologous ; Erythrocytes
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Indium-labelling of red cells is hampered by its high elution rate and short physical half-life. From a study of 23 pathological cases, it is demonstrated that the simultaneous study of 111In- and 51Cr-labelled red cells could only be useful in haemolytic anaemias in which the mechanisms (corpuscular or extra-corpuscular) of the cell destruction is in question.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00252193

    Articles: DFG German National Licenses