Search Results - (Author, Cooperation:Y. J. Cho)

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  1. 1
    A. S. Morrissy ; L. Garzia ; D. J. Shih ; S. Zuyderduyn ; X. Huang ; P. Skowron ; M. Remke ; F. M. Cavalli ; V. Ramaswamy ; P. E. Lindsay ; S. Jelveh ; L. K. Donovan ; X. Wang ; B. Luu ; K. Zayne ; Y. Li ; C. Mayoh ; N. Thiessen ; E. Mercier ; K. L. Mungall ; Y. Ma ; K. Tse ; T. Zeng ; K. Shumansky ; A. J. Roth ; S. Shah ; H. Farooq ; N. Kijima ; B. L. Holgado ; J. J. Lee ; S. Matan-Lithwick ; J. Liu ; S. C. Mack ; A. Manno ; K. A. Michealraj ; C. Nor ; J. Peacock ; L. Qin ; J. Reimand ; A. Rolider ; Y. Y. Thompson ; X. Wu ; T. Pugh ; A. Ally ; M. Bilenky ; Y. S. Butterfield ; R. Carlsen ; Y. Cheng ; E. Chuah ; R. D. Corbett ; N. Dhalla ; A. He ; D. Lee ; H. I. Li ; W. Long ; M. Mayo ; P. Plettner ; J. Q. Qian ; J. E. Schein ; A. Tam ; T. Wong ; I. Birol ; Y. Zhao ; C. C. Faria ; J. Pimentel ; S. Nunes ; T. Shalaby ; M. Grotzer ; I. F. Pollack ; R. L. Hamilton ; X. N. Li ; A. E. Bendel ; D. W. Fults ; A. W. Walter ; T. Kumabe ; T. Tominaga ; V. P. Collins ; Y. J. Cho ; C. Hoffman ; D. Lyden ; J. H. Wisoff ; J. H. Garvin, Jr. ; D. S. Stearns ; L. Massimi ; U. Schuller ; J. Sterba ; K. Zitterbart ; S. Puget ; O. Ayrault ; S. E. Dunn ; D. P. Tirapelli ; C. G. Carlotti ; H. Wheeler ; A. R. Hallahan ; W. Ingram ; T. J. MacDonald ; J. J. Olson ; E. G. Van Meir ; J. Y. Lee ; K. C. Wang ; S. K. Kim ; B. K. Cho ; T. Pietsch ; G. Fleischhack ; S. Tippelt ; Y. S. Ra ; S. Bailey ; J. C. Lindsey ; S. C. Clifford ; C. G. Eberhart ; M. K. Cooper ; R. J. Packer ; M. Massimino ; M. L. Garre ; U. Bartels ; U. Tabori ; C. E. Hawkins ; P. Dirks ; E. Bouffet ; J. T. Rutka ; R. J. Wechsler-Reya ; W. A. Weiss ; L. S. Collier ; A. J. Dupuy ; A. Korshunov ; D. T. Jones ; M. Kool ; P. A. Northcott ; S. M. Pfister ; D. A. Largaespada ; A. J. Mungall ; R. A. Moore ; N. Jabado ; G. D. Bader ; S. J. Jones ; D. Malkin ; M. A. Marra ; M. D. Taylor
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-01-14
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2012-02-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Clonal Evolution/*genetics ; CpG Islands/genetics ; DNA Methylation ; DNA Transposable Elements/genetics ; Disease Models, Animal ; Genes, p53/genetics ; Germ-Line Mutation/genetics ; Humans ; Li-Fraumeni Syndrome/complications/genetics ; Medulloblastoma/complications/*genetics/*pathology ; Mice ; Mutagenesis, Insertional ; Neoplasm Metastasis/*genetics/*pathology ; Survival Rate
    Published by:
    http://www.nature.com/

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  3. 3
    P. A. Northcott ; D. J. Shih ; J. Peacock ; L. Garzia ; A. S. Morrissy ; T. Zichner ; A. M. Stutz ; A. Korshunov ; J. Reimand ; S. E. Schumacher ; R. Beroukhim ; D. W. Ellison ; C. R. Marshall ; A. C. Lionel ; S. Mack ; A. Dubuc ; Y. Yao ; V. Ramaswamy ; B. Luu ; A. Rolider ; F. M. Cavalli ; X. Wang ; M. Remke ; X. Wu ; R. Y. Chiu ; A. Chu ; E. Chuah ; R. D. Corbett ; G. R. Hoad ; S. D. Jackman ; Y. Li ; A. Lo ; K. L. Mungall ; K. M. Nip ; J. Q. Qian ; A. G. Raymond ; N. T. Thiessen ; R. J. Varhol ; I. Birol ; R. A. Moore ; A. J. Mungall ; R. Holt ; D. Kawauchi ; M. F. Roussel ; M. Kool ; D. T. Jones ; H. Witt ; L. A. Fernandez ; A. M. Kenney ; R. J. Wechsler-Reya ; P. Dirks ; T. Aviv ; W. A. Grajkowska ; M. Perek-Polnik ; C. C. Haberler ; O. Delattre ; S. S. Reynaud ; F. F. Doz ; S. S. Pernet-Fattet ; B. K. Cho ; S. K. Kim ; K. C. Wang ; W. Scheurlen ; C. G. Eberhart ; M. Fevre-Montange ; A. Jouvet ; I. F. Pollack ; X. Fan ; K. M. Muraszko ; G. Y. Gillespie ; C. Di Rocco ; L. Massimi ; E. M. Michiels ; N. K. Kloosterhof ; P. J. French ; J. M. Kros ; J. M. Olson ; R. G. Ellenbogen ; K. Zitterbart ; L. Kren ; R. C. Thompson ; M. K. Cooper ; B. Lach ; R. E. McLendon ; D. D. Bigner ; A. Fontebasso ; S. Albrecht ; N. Jabado ; J. C. Lindsey ; S. Bailey ; N. Gupta ; W. A. Weiss ; L. Bognar ; A. Klekner ; T. E. Van Meter ; T. Kumabe ; T. Tominaga ; S. K. Elbabaa ; J. R. Leonard ; J. B. Rubin ; L. M. Liau ; E. G. Van Meir ; M. Fouladi ; H. Nakamura ; G. Cinalli ; M. Garami ; P. Hauser ; A. G. Saad ; A. Iolascon ; S. Jung ; C. G. Carlotti ; R. Vibhakar ; Y. S. Ra ; S. Robinson ; M. Zollo ; C. C. Faria ; J. A. Chan ; M. L. Levy ; P. H. Sorensen ; M. Meyerson ; S. L. Pomeroy ; Y. J. Cho ; G. D. Bader ; U. Tabori ; C. E. Hawkins ; E. Bouffet ; S. W. Scherer ; J. T. Rutka ; D. Malkin ; S. C. Clifford ; S. J. Jones ; J. O. Korbel ; S. M. Pfister ; M. A. Marra ; M. D. Taylor
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-07-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Carrier Proteins/genetics ; Cerebellar Neoplasms/*classification/*genetics/metabolism ; Child ; DNA Copy Number Variations/genetics ; Gene Duplication/genetics ; Genes, myc/genetics ; Genome, Human/*genetics ; Genomic Structural Variation/*genetics ; Genomics ; Hedgehog Proteins/metabolism ; Humans ; Medulloblastoma/*classification/*genetics/metabolism ; NF-kappa B/metabolism ; Nerve Tissue Proteins/genetics ; Oncogene Proteins, Fusion/genetics ; Proteins/genetics ; RNA, Long Noncoding ; Signal Transduction ; Transforming Growth Factor beta/metabolism ; Translocation, Genetic/genetics
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    http://www.nature.com/

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  4. 4
    S. C. Mack ; H. Witt ; R. M. Piro ; L. Gu ; S. Zuyderduyn ; A. M. Stutz ; X. Wang ; M. Gallo ; L. Garzia ; K. Zayne ; X. Zhang ; V. Ramaswamy ; N. Jager ; D. T. Jones ; M. Sill ; T. J. Pugh ; M. Ryzhova ; K. M. Wani ; D. J. Shih ; R. Head ; M. Remke ; S. D. Bailey ; T. Zichner ; C. C. Faria ; M. Barszczyk ; S. Stark ; H. Seker-Cin ; S. Hutter ; P. Johann ; S. Bender ; V. Hovestadt ; T. Tzaridis ; A. M. Dubuc ; P. A. Northcott ; J. Peacock ; K. C. Bertrand ; S. Agnihotri ; F. M. Cavalli ; I. Clarke ; K. Nethery-Brokx ; C. L. Creasy ; S. K. Verma ; J. Koster ; X. Wu ; Y. Yao ; T. Milde ; P. Sin-Chan ; J. Zuccaro ; L. Lau ; S. Pereira ; P. Castelo-Branco ; M. Hirst ; M. A. Marra ; S. S. Roberts ; D. Fults ; L. Massimi ; Y. J. Cho ; T. Van Meter ; W. Grajkowska ; B. Lach ; A. E. Kulozik ; A. von Deimling ; O. Witt ; S. W. Scherer ; X. Fan ; K. M. Muraszko ; M. Kool ; S. L. Pomeroy ; N. Gupta ; J. Phillips ; A. Huang ; U. Tabori ; C. Hawkins ; D. Malkin ; P. N. Kongkham ; W. A. Weiss ; N. Jabado ; J. T. Rutka ; E. Bouffet ; J. O. Korbel ; M. Lupien ; K. D. Aldape ; G. D. Bader ; R. Eils ; P. Lichter ; P. B. Dirks ; S. M. Pfister ; A. Korshunov ; M. D. Taylor
    Nature Publishing Group (NPG)
    Published 2014
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    Publication Date:
    2014-02-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Brain Neoplasms/drug therapy/genetics ; CpG Islands/*genetics ; DNA Methylation/drug effects ; Embryonic Stem Cells/metabolism ; Ependymoma/drug therapy/*genetics ; Epigenesis, Genetic/*genetics ; Epigenomics ; Female ; Gene Expression Regulation, Neoplastic ; Gene Silencing/drug effects ; Histones/drug effects/metabolism ; Humans ; Infant ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Mutation/genetics ; Phenotype ; Polycomb Repressive Complex 2/metabolism ; Prognosis ; Rhombencephalon/pathology ; Xenograft Model Antitumor Assays
    Published by:
    http://www.nature.com/

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  5. 5
    Staff View
    Publication Date:
    2012-07-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cerebellar Neoplasms/classification/*genetics ; Child ; DEAD-box RNA Helicases/chemistry/genetics/metabolism ; DNA Helicases/chemistry/genetics ; DNA-Binding Proteins/genetics ; Exome/*genetics ; Genome, Human/*genetics ; Hedgehog Proteins/metabolism ; Histone-Lysine N-Methyltransferase/genetics/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; LIM Domain Proteins/genetics ; Medulloblastoma/classification/*genetics ; Models, Molecular ; Mutation/*genetics ; Neoplasm Proteins/genetics ; Nuclear Proteins/chemistry/genetics ; Promoter Regions, Genetic/genetics ; Protein Structure, Tertiary/genetics ; Proto-Oncogene Proteins/genetics ; Receptors, Cell Surface/genetics ; Repressor Proteins/genetics ; Signal Transduction ; TCF Transcription Factors/metabolism ; Transcription Factors/chemistry/genetics ; Tumor Suppressor Protein p53/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics/metabolism
    Published by:
    http://www.nature.com/

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  6. 6
    E. C. Dykhuizen ; D. C. Hargreaves ; E. L. Miller ; K. Cui ; A. Korshunov ; M. Kool ; S. Pfister ; Y. J. Cho ; K. Zhao ; G. R. Crabtree
    Nature Publishing Group (NPG)
    Published 2013
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    Publication Date:
    2013-05-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Anaphase ; Animals ; Antigens, Neoplasm/genetics/*metabolism ; Cell Cycle Checkpoints ; Chromatids/metabolism ; Chromatin Assembly and Disassembly ; Chromosome Segregation ; DNA Helicases/deficiency/genetics/*metabolism ; DNA Replication ; DNA Topoisomerases, Type II/genetics/*metabolism ; DNA, Catenated/*chemistry/*metabolism ; DNA-Binding Proteins/genetics/*metabolism ; Fibroblasts ; G2 Phase ; HEK293 Cells ; Humans ; Medulloblastoma/genetics ; Mice ; Mitosis ; Nuclear Proteins/deficiency/genetics/*metabolism ; Transcription Factors/deficiency/genetics/*metabolism
    Published by:
    http://www.nature.com/

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  7. 7
    D. T. Jones ; N. Jager ; M. Kool ; T. Zichner ; B. Hutter ; M. Sultan ; Y. J. Cho ; T. J. Pugh ; V. Hovestadt ; A. M. Stutz ; T. Rausch ; H. J. Warnatz ; M. Ryzhova ; S. Bender ; D. Sturm ; S. Pleier ; H. Cin ; E. Pfaff ; L. Sieber ; A. Wittmann ; M. Remke ; H. Witt ; S. Hutter ; T. Tzaridis ; J. Weischenfeldt ; B. Raeder ; M. Avci ; V. Amstislavskiy ; M. Zapatka ; U. D. Weber ; Q. Wang ; B. Lasitschka ; C. C. Bartholomae ; M. Schmidt ; C. von Kalle ; V. Ast ; C. Lawerenz ; J. Eils ; R. Kabbe ; V. Benes ; P. van Sluis ; J. Koster ; R. Volckmann ; D. Shih ; M. J. Betts ; R. B. Russell ; S. Coco ; G. P. Tonini ; U. Schuller ; V. Hans ; N. Graf ; Y. J. Kim ; C. Monoranu ; W. Roggendorf ; A. Unterberg ; C. Herold-Mende ; T. Milde ; A. E. Kulozik ; A. von Deimling ; O. Witt ; E. Maass ; J. Rossler ; M. Ebinger ; M. U. Schuhmann ; M. C. Fruhwald ; M. Hasselblatt ; N. Jabado ; S. Rutkowski ; A. O. von Bueren ; D. Williamson ; S. C. Clifford ; M. G. McCabe ; V. P. Collins ; S. Wolf ; S. Wiemann ; H. Lehrach ; B. Brors ; W. Scheurlen ; J. Felsberg ; G. Reifenberger ; P. A. Northcott ; M. D. Taylor ; M. Meyerson ; S. L. Pomeroy ; M. L. Yaspo ; J. O. Korbel ; A. Korshunov ; R. Eils ; S. M. Pfister ; P. Lichter
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-07-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Aging/genetics ; Amino Acid Sequence ; Cell Transformation, Neoplastic ; Cerebellar Neoplasms/classification/diagnosis/*genetics/pathology ; Child ; Chromatin/metabolism ; Chromosomes, Human/genetics ; DEAD-box RNA Helicases/genetics ; DNA Helicases/genetics ; DNA-Binding Proteins/genetics ; Genome, Human/*genetics ; Genomics ; Hedgehog Proteins/metabolism ; High-Throughput Nucleotide Sequencing ; Histone Demethylases/genetics ; Humans ; Medulloblastoma/classification/diagnosis/*genetics/pathology ; Methylation ; Mutation/genetics ; Mutation Rate ; Neoplasm Proteins/genetics ; Nuclear Proteins/genetics ; Oncogene Proteins, Fusion/genetics ; Phosphoprotein Phosphatases/genetics ; Polyploidy ; Receptors, Cell Surface/genetics ; Sequence Analysis, RNA ; Signal Transduction ; T-Box Domain Proteins/genetics ; Transcription Factors/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics
    Published by:
    http://www.nature.com/

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  8. 8
    Staff View
    Publication Date:
    2018-02-28
    Publisher:
    Wiley-Blackwell
    Print ISSN:
    0007-0963
    Electronic ISSN:
    1365-2133
    Topics:
    Medicine
    Published by:
    http://www.wiley.com/wiley-blackwell

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Choi, J. Y., Cho, H., Ahn, S. J., Lee, J. H., Ryu, Y. H., Lee, M. S., Lyoo, C. H.
    The Society of Nuclear Medicine (SNM)
    Published 2018
    Staff View
    Publication Date:
    2018-01-03
    Publisher:
    The Society of Nuclear Medicine (SNM)
    Print ISSN:
    0022-3123
    Topics:
    Medicine
    Published by:
    http://www.snm.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Kim, E. J., Kong, M.-S., Park, S. G., Mizumori, S. J. Y., Cho, J., Kim, J. J.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-04-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Electronic ISSN:
    2375-2548
    Topics:
    Natural Sciences in General
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  11. 11
    Cho, Y.-J. ; Alamed, J. ; McClements, D.J. ; Decker, E.A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2003
    Staff View
    ISSN:
    1750-3841
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    : Our research determined whether chelators could influence physical location and prooxidative activity of lipid-phase iron in oil-in-water emulsions. Corn oil saturated with ferric ions was used to produce polyoxyethylene 10 lauryl ether-stabilized oil-in-water emulsions. Continuous-phase iron concentrations increased with increasing chelator concentrations (10 to 100 μM) and storage time (1 to 7 d). At pH 3.0, the concentration of continuous-phase iron was higher in the presence of EDTA and sodium tripolyphosphate (STPP) than citrate. STPP and EDTA were more effective than citrate at inhibiting lipid oxidation at pH 3.0. These results indicate that chelators can increase the transfer of iron in lipid to the aqueous phase, thus altering its prooxidant activity in oil-in-water emulsions.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2621.2003.tb07000.x

    Articles: DFG German National Licenses
  12. 12
    Cho, Y.-J. ; Hong, S.-J. ; Moon, H.-B.

    Oxford BSL : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Although there is convincing evidence that human B cells can be induced to produce IgE by a combination of interleukin 4 (IL-4) and hydrocortisone (HC) in atopic subjects, it is still uncertain if this performs the same functions in allergen-specific IgE synthesis.〈section xml:id="abs1-2"〉〈title type="main"〉ObjectiveThis study was designed to investigate the differences of IgE regulation between atopics and nonatopics, interactions of HC with IL-4, and the correlation between in vitro total IgE, allergen-specific IgE synthesis and serum IgE levels.〈section xml:id="abs1-3"〉〈title type="main"〉MethodsPeripheral blood mononuclear cells (PBMCs) from 16 atopic asthma patients sensitive to Dermatophagoides farinae and seven nonatopic controls were cultured with IL-4 and/or HC. Total IgE and D. farinae-specific IgE in culture supernatant were measured by ELISA and FAST.〈section xml:id="abs1-4"〉〈title type="main"〉ResultsIL-4 increased total IgE synthesis in PBMCs from both atopics and nonatopics, whereas, HC had this effect only in some atopics who showed spontaneous IgE production in vitro. HC acted synergistically with IL-4 in total IgE synthesis. Their effects were more remarkable in cases with lower total serum IgE levels. PBMCs from eight of 16 atopics produced D. farinae-specific IgE in vitro either spontaneously or by IL-4 and/or HC. HC had more profound effects than IL-4 in these patients. They also showed higher total IgE synthesis by HC, and higher specific serum IgE levels than the others. IL-4 and/or HC did not induce any D. farinae-specific IgE synthesis by PBMCs from nonatopics.〈section xml:id="abs1-5"〉〈title type="main"〉ConclusionHC had a more profound effect than IL-4 on the induction of D. farinae-specific IgE synthesis in atopic patients with high serum allergen specific IgE levels. Further studies to determine the causes of these effects, such as the presence of long lived allergen specific B cells as the result of the priming effect of IL-4 in vivo, may be needed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2222.2000.00991.x

    Articles: DFG German National Licenses
  13. 13
    CHO, S. H. ; SEO, J. Y. ; CHOI, D. C. ; YOON, H. J. ; CHO, Y. J. ; MIN, K. U. ; LEE, G. K. ; SEO, J. W. ; KIM, Y. Y.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background There have been many studies concerning pathological changes in bronchial mucosa from asthmatics; however, few studies has been carried out to evaluate pathological changes according to the severity of asthma.Objective This study was designed to evaluate the cellular components in bronchoalveolar lavage fluid (BALF) and histologicai abnormalities in asthmatics according to the severity ot asthma.Methods Bronchoalveolar lavages, bronchoscopic biopsies and ultrastructural examinations were performed in 13 asthmatics and 11 (BAL) or four (biopsies) non-asthmatic controls. The proportions of epithelial cells and eosinophils in BALF were significantly increased in asthmatics and showed significant correlations with PC20Meth which reflects bronchial hyperresponsiveness. Light microscopic examination revealed loss of epithelium, inllammatory cell infiltrations and thickening of the basement membrane which also showed significant correlation with PC20Meth. Hypertrophy of airway smooth muscles and hyperplasia of mucous glands were prominent in asthmatics but there was no difference according to the severity of asthma. Ultra-structural examination revealed that basement membrane thickening on light microscopic examination is due to the increased subepithelial collagen deposition with normal thickeness of basal lamina.Conclusion These data suggest that loss of epithelial cells, infiltration of inflammatory cells, especially eosinophils, and increased deposition of subepithelial collagen play major roles in determining the severity of asthma and non-specific bronchial hyperresponsiveness.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2222.1996.tb00510.x

    Articles: DFG German National Licenses
  14. 14
    Choi, Y.J. ; Lanier, T.C. ; Lee, H.G. ; Cho, Y.-J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1999
    Staff View
    ISSN:
    1750-3841
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Two alkaline proteinases (A and B) were isolated and found to be composed of homogeneous subunits. These proteinases, A and B, were concentrated 62.9-and 986.5-fold compared to the crude muscle extract, with molecular weights of 707,000 and 450,000, respectively. Both are probably serine type proteinases, and optimum caseinolytic activity was shown at pH 8.0 and 55 °C. Both degraded actomyosin under similar conditions. Enzyme A had higher thermal stability than B. The residual activities of A and B in 3.6% NaCl solution were 95% and 85%. These data suggest that these proteinases are involved in the softening of menhaden surimi gels which occurs during heating at 50 to 70 °C.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2621.1999.tb15908.x

    Articles: DFG German National Licenses
  15. 15
    Choi, Y.J. ; Cho, Y.-J. ; Lanier, T.C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1999
    Staff View
    ISSN:
    1750-3841
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Two proteinases (A and B) were isolated from Atlantic menhaden muscle with molecular weights of 112,000 and 90,500 daltons, respectively. Proteinase B had higher activity than A for protein substrates except casein; proteinase B had no caseinolytic activity. Both proteinases hydrolyzed synthetic substrates such as Z-Phe-Arg-NMecand TAME, but not BAEE and BAPNA. Optimum Z-Phe-Arg-NMec hydrolyzing activity was shown at pH 7.4, 40 to 50 °C for both proteinases A and B. Activities of A and B in the presence of 3.0% NaCl were reduced to 71.2% and 62.2%, respectively. Both proteinases were inhibited by 1 mM TLCK, 1 mM benzamidine, 1% egg white, and 1% bovine plasma hydrolysate. Proteinases A and B are most likely tryptic serine type proteinases.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2621.1999.tb15909.x

    Articles: DFG German National Licenses
  16. 16
    Cho, K-H. ; Lee, S-H. ; Kim, C-W. ; Jeon, Y-K. ; Kwon, I-H. ; Cho, Y-J. ; Lee, S-K. ; Suh, D-H. ; Chung, J-H. ; Yoon, T-Y. ; Lee, S-J.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background  There are many reports of patients with a severe hydroa vacciniforme (HV)-like eruption in which cutaneous lesions occur in both sun-exposed and non-exposed areas, unlike in true HV. Several patients have died from a malignant haematological neoplasm. In most cases, a latent Epstein–Barr virus (EBV) infection has been detected in the skin lesions.Objectives  To describe the clinical and laboratory features of six additional patients with an EBV-associated HV-like eruption.Methods  The clinical, histological and immunohistochemical features were reviewed. T-cell receptor γ gene rearrangements were studied using polymerase chain reaction (PCR) and heteroduplex analysis. In-situ hybridization was performed to detect mRNA for EBV in skin biopsy specimens. PCR was performed to screen for EBV infection in the skin lesions of three patients and blood of two patients. Photoprovocation with repeated ultraviolet (UV) A exposure was performed in three patients.Results  The severity of the skin lesions and the clinical course varied among the patients. Skin lesions were induced by repeated UVA exposure in three patients and a latent EBV infection was demonstrated in the photoprovoked lesions.Conclusions  Three different clinical courses were found in six patients with an HV-like eruption associated with chronic EBV infection: (i) spontaneous remission; (ii) clearing after photoprotection; and (iii) continuous recurrence irrespective of sun exposure. It is possible that there are two patterns of HV-like eruption associated with chronic EBV infection. One is characterized by recurrent necrotic papulovesicles of the face and the other by nodules and facial swelling. It was demonstrated that the skin lesions could be triggered by repeated UVA exposure in the patients showing recurrent necrotic papulovesicles of the face.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2133.2004.06038.x

    Articles: DFG German National Licenses
  17. 17
    Pathak, H. K. ; Kang, S. M. ; Cho, Y. J.
    Springer
    Published 1998
    Staff View
    ISSN:
    1572-9141
    Keywords:
    Weakly commuting ; compatible and weakly compatible mappings ; asymptotically regular sequence ; coincidence point and fixed point ; Kannan mapping
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    Abstract In this paper we first prove some coincidence and fixed point theorems for nonlinear hybrid generalized contractions on metric spaces. Secondly, using the concept of an asymptotically regular sequence, we give some fixed point theorems for Kannan type multi-valued mappings on metric spaces. Our main results improve and extend several known results proved by other authors.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1022897706230

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1432-0614
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Summary A process for l-phenylalanine production was studied using a tyrosine auxotrophic regulatory mutant of Escherichia coli, resistant to both β-2-thienyl-dl-alanine and p-fluoro-dl-phenylalanine. Fermentations were carried out in a 30-1 fermentor with intermittent feeding of glucose plus phosphate. The mutant accumulated l-phenylalanine in the fermentation broth up to 15 g/l at pH 7.0 and 33°C. Column chromatography on a strong cation exchanger was employed as the most effective step in the purification of l-phenyl-alanine from the broth. This step brought about 4-fold concentration of the product with 96% recovery.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00250029

    Articles: DFG German National Licenses
  19. 19
    Zhu, J. ; Zhong, C. K. ; Cho, Y. J.
    Springer
    Published 2000
    Staff View
    ISSN:
    1573-2878
    Keywords:
    Variational principles ; preorder ; vector optimization ; transfinite induction
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    Abstract In this note, we present a generalization of the celebrated Ekeland variational principle and its equivalent forms. The results presented in this paper unify, improve, and extend the corresponding result in Refs. 1–7.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1004619426652

    Articles: DFG German National Licenses
  20. 20
    Cho, Y. J. ; Beom, H. G. ; Earmme, Y. Y.
    Springer
    Published 1994
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract A mutual integral, which has the conservation property is applied to the problem of an interfacial crack. The stress intensity factors K 1, K 2, K 3 and T-stress for the problem in an infinite medium are easily obtained by using the mutual integral without solving the boundary value problem. In doing so the auxiliary solutions are required and they are taken from the known asymptotic solutions. This method is amenable to numerical evaluation of the stress intensity factors and T-stress if the interfacial crack in a finite medium is considered.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00017143

    Articles: DFG German National Licenses