Search Results - (Author, Cooperation:Y. Igarashi)

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  1. 1
  2. 2
    B. Zhen ; C. W. Hsu ; Y. Igarashi ; L. Lu ; I. Kaminer ; A. Pick ; S. L. Chua ; J. D. Joannopoulos ; M. Soljacic
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-09-10
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    E. A. Mullins ; R. Shi ; Z. D. Parsons ; P. K. Yuen ; S. S. David ; Y. Igarashi ; B. F. Eichman
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-11-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Bacillus cereus/*enzymology ; Base Pairing ; *Biocatalysis ; Catalytic Domain ; Crystallography, X-Ray ; DNA Adducts/*chemistry/*metabolism ; DNA Damage ; DNA Glycosylases/*chemistry/*metabolism ; *DNA Repair ; Indoles ; Models, Molecular ; Pyrroles
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Igarashi, Y. ; Fujino, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1991
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    For the purpose of investigating the interdiffusion properties between thin Y–Ba–Cu–O films of compositions near YBa2Cu3O7−y and MgO substrates, time evolution of both Rutherford backscattering spectra and scanning electron microscope images during annealing were observed. Actual diffusivities of Y, Ba, and Cu elements in the MgO substrates have been found to be extremely smaller than the values previously reported. The origins of the discrepancies between the present and the previously reported results are discussed in connection with the morphology variation of the thin Y–Ba–Cu–O films on the MgO substrates during heat treatments.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Igarashi, Y. ; Fujino, Y. ; Suzuki, N. ; Iimura, K.

    [S.l.] : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Interdiffusion between sputter-deposited thin Y-Ba-Cu-O films and Al2O3 substrates has been studied by applying 3.2 MeV 4He+ Rutherford backscattering spectrometry. The effects of morphology variation of the films during annealing have been successfully excluded using the data of thickness distribution measured by applying atomic force microscopy. The formalism used for the analysis is presented. The obtained values of the diffusivities are more than 20 times smaller than those reported by other workers.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    URANO, K. ; YOSHIBA, Y. ; NANJO, T. ; IGARASHI, Y. ; SEKI, M. ; SEKIGUCHI, F. ; YAMAGUCHI-SHINOZAKI, K. ; SHINOZAKI, K.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-3040
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    To characterize the genes for enzymes involved in the biosynthesis of polyamines (PAs), their expression profiles were investigated and the levels of PAs in Arabidopsis thaliana quantified. In the Arabidopsis genome, eight genes involved in PAs biosynthesis were identified and the expression profiles of these genes were analysed, not only under abiotic stress to determine whether they were stress-inducible, constitutive, or stress-repressible, but also in various organs to show their tissue specificity. AtADC2 and AtSPMS mRNAs, encoding arginine decarboxylase and spermine synthase, clearly increased in response to NaCl and dehydration and abscisic acid treatments. Stress-inducible accumulation of AtADC2 mRNA correlated with putrescine (Put) accumulation under NaCl and dehydration treatments. In a cold condition, AtSAMDC2 mRNA increased significantly. AtADC2 and AtSAMDC2 mRNA were expressed in sexual organs such as flowers, buds and immature siliques. PAs also accumulated in sexual organs. These results suggest that the transcripts of eight genes involved in PA biosynthesis show different profiles of expression not only in response to environmental stress but also during plant development.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    IGARASHI, Y. ; KUROSAWA, M. ; ISHIKAWA, O. ; MIYACHI, Y. ; SAITO, H. ; EBISAWA, M. ; IIKURA, Y. ; YANAGIDA, M. ; UZUMAKI, H. ; NAKAHATA, T.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background The mtist cell is one of the important cells In the pathogenesis of allergic disorders. However, isolating human mast cells is a laborious procedure. Recently, cultured human mast cells raised from umbilical cord blood cells have become available. It is necessary to examine whether these cells are useful in investigating the role of mast cells in human diseases.Objective The phenotype of mast cells depends on their anatomical sites. To examine which phetiotype of mast cells these cultured mast cells most closely resemble, their ability to release was investigated.Methods The mast cells were raised from human umbilical cord blood cells in the presence of stem cell factor and interIeukin-6. To determine the mast cell subtypes, the mast cells were immunocytochemically stained for tryptase and chymase. The cultured mast cells were then stimulated with various secretagogues, and histamine release was measured by a fluorometric technique using high-performance liquid chromatography. Results The immunocytochemical staining for mast cell proteases revealed that virtually all cells contained tryptase, the definitive marker of mast cells, and that about a quarter of the cells contained chymase. Anti-TgE effectively stimulated these mast cells to release histamine in a dose-dependent, lime-dependent manner. The release was completed in about 30 min. One of the non-specific stimuli, calcium ionophore A23I87. also induced histamine release in a dose-dependent, time-dependent manner. In contrast, compound 48/80 and substance P failed to induce histamine release from these cells. Conclusion Cultured human mast cells resemble lung mast cells in their ability to release histamine. They will help in studying the functional properties of human mast cells and may contribute to clarifying the pathophysiology of human allergic diseases.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Yamashita, S. ; Igarashi, Y. ; Ai, M.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2842
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    summary  Occlusal conditions at the retruded contact position (RCP) have been thought to be among the aetiological factors for temporomandibular disorders. However, the role of these occlusal factors still remain unclear. The purpose of a series of studies was to investigate the locations of RCP contacts and to discuss their implication by the authors. In the study reported here, the influence of the operator's skill on bite registration was surveyed. Eighty-six dental students were selected as subjects. One specialist in prosthetic dentistry moved the subject's mandible up and down while guiding it gently backward until it rotated on its retruded axis. Once the initial tooth contacts were established, the operator checked them by using a thin articulating paper (direct method). On the other hand, six younger operators following precise instruction from the specialist about the technique of jaw guidance examined each of the subjects for location of RCP contacts using the indirect method. Silicone-based impression material was used for bite registration while the subject kept the jaw at this contact position (indirect method). Wilcoxon signed rank test was applied to evaluate differences between the expert operator and six younger operators regarding locations of RCP contacts. Results from the expert operator (direct method) showed that tooth contact at the first premolar was most frequently observed and the number of subjects who possessed unilateral tooth contacts was more than that with bilateral tooth contacts. On the other hand, in the case of the indirect method performed by younger operators, tooth contact patterns significantly differed from those of the direct method.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Igarashi, Y. ; Ogata, A. ; Kuroiwa, A. ; Wang, C. H.

    Oxford, UK : Blackwell Science Ltd
    Published 1999
    Staff View
    ISSN:
    1365-2842
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Three types of retainers (wrought wire clasp, Aker's cast clasp, and conical crown telescopic retainer) designed for distal-extension removable partial dentures (RPDs) were assessed in two Kennedy class I patients’ mouths. The assessment, included the ratio of denture base shearing load and mobility of the terminal abutments when loaded on a free-end RPD occlusal surface. The mean values of denture base shearing ratios of wrought wire clasp, Aker's clasp and conical crown telescope were 60, 42 and 20%, respectively. The abutment mobility of the three types of retainers were all within the ‘mobile ability area’ except the wrought wire clasp for patient A's right side. The greatest tooth mobility was observed with the wrought wire clasps, followed by Aker's clasp and the conical crown telescopic retainer. From the analysis the following was concluded: (i) different retainers do influence the occlusal load distribution; (ii) the occlusal load distributed to the free-end saddle is closely related to the connecting rigidity of the retainer; (iii) mucosal support has an indispensable role in sharing the occlusal load with various retainers, even the rigid telescopic retainer.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    YAMASHITA, S. ; IGARASHI, Y. ; AI, M.

    Oxford, UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2842
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Summary Occlusal conditions at the retruded contact position (RCP) have been thought to be among the aetiological factors for temporomandibular disorders. However, the role of these occlusal factors remains still unclear. The purpose of this series of studies was to investigate the locations of RCP contacts and to discuss their meaning. In this part of the study, two different methods for bite registration at the RCP have been compared. Twenty dentists were selected as subjects for this study. One expert operator moved the subject's mandible up and down while guiding it gently backward until rotating on its retruded axis. Once the initial tooth contacts were established, the operator checked them using a thin articulating paper (direct method). Silicone-based impression material was used for bite registration while the subject kept the jaw at this contact position (indirect method). Differences between the two registration methods regarding locations of tooth contacts were evaluated. Results from the direct method showed that tooth contact at the first premolar was most frequently observed. Statistical difference was not shown between the two registration methods regarding locations of RCP contacts.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Mazurek, N. ; Megidish, T. ; Hakomori, S. ; Igarashi, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Igarashi, Y. ; Kitamura, K. ; Zhou, Q. ; Hakomori, S.i.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Keywords:
    [abr] EDRA; EGF-dependent receptor autophosphorylation ; [abr] EGF; epidermal growth factor ; [abr] PAF; platelet-activating factor ; [abr] PC; phosphatidylcholine ; [abr] PDME; phosphatidyldimethylethanolamine ; [abr] PE; phosphatidylethanolamine ; [abr] PI; phosphatidylinositol ; [abr] PMME; phosphatidylmonomethylethanolamine ; [abr] PS; phosphatidylserine ; [abr] SM; sphingomyelin
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Narisawa, K. ; Igarashi, Y. ; Otomo, H. ; Tada, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    IGARASHI, Y. ; YAOI, Y.

    [s.l.] : Nature Publishing Group
    Published 1975
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Kondo and Sakai6 extracted a cell aggregation factor by dissociating sea urchin embryos with 1 M urea-5 mM EDTA solution and showed that this factor was precipitated in the presence of calcium ions. This method was used here for the extraction and purification of the exudate of cultured ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Ohta, H. ; Ruan, F.Q. ; Hakomori, S. ; Igarashi, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    0301-4622
    Keywords:
    (Limulus polyphemus) ; Ca^2^+ ; Dissociation ; Hemocyanin ; Solution X-ray scattering
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    0922-338X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Nishihara, H. ; Igarashi, Y. ; Kodama, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0922-338X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Yaguchi, T. ; Chung, S.Y. ; Igarashi, Y. ; Kodama, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0922-338X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses