Search Results - (Author, Cooperation:Y. Hirano)

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  1. 1
    Staff View
    Publication Date:
    2014-11-22
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alu Elements ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/*pharmacology/therapeutic use ; Apoptosis/drug effects ; Carrier Proteins/metabolism ; Caspase 1/metabolism ; Choroidal Neovascularization/drug therapy ; Disease Models, Animal ; Geographic Atrophy/drug therapy ; Graft vs Host Disease/drug therapy ; Hepatitis/drug therapy ; Inflammasomes/*drug effects ; Liver/drug effects ; Mice ; Receptors, Purinergic P2X7/metabolism ; Retinal Pigment Epithelium/drug effects/metabolism/physiology ; Reverse Transcriptase Inhibitors/*pharmacology/therapeutic use
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Y. Hirano ; T. Masuda ; S. Naganos ; M. Matsuno ; K. Ueno ; T. Miyashita ; J. Horiuchi ; M. Saitoe
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-01-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; CREB-Binding Protein/metabolism ; Cyclic AMP Response Element-Binding Protein/metabolism ; Cycloheximide/pharmacology ; Drosophila/*physiology ; Drosophila Proteins/biosynthesis/*metabolism ; *Fasting ; *Memory, Long-Term/drug effects ; Mushroom Bodies/physiology ; Neurons/physiology ; Protein Synthesis Inhibitors/pharmacology ; Transcription Factors/*metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    S. Niwa ; L. J. Yu ; K. Takeda ; Y. Hirano ; T. Kawakami ; Z. Y. Wang-Otomo ; K. Miki
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-03-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Bacteriochlorophylls/chemistry/metabolism ; Calcium/metabolism ; Chromatiaceae/*chemistry ; Coenzymes/chemistry/metabolism ; Crystallography, X-Ray ; Light-Harvesting Protein Complexes/*chemistry/metabolism ; Models, Molecular ; Protein Binding ; Protein Structure, Quaternary ; Protein Subunits/chemistry/metabolism ; Ubiquinone/metabolism ; Xanthophylls/chemistry/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2011-02-08
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alu Elements/*genetics ; Animals ; Cell Death ; Cell Survival ; Cells, Cultured ; DEAD-box RNA Helicases/*deficiency/genetics/metabolism ; Gene Knockdown Techniques ; Humans ; Macular Degeneration/*genetics/*pathology ; Mice ; MicroRNAs/metabolism ; Molecular Sequence Data ; Oligonucleotides, Antisense ; Phenotype ; RNA/*genetics/*metabolism ; Retinal Pigment Epithelium/enzymology/metabolism/pathology ; Ribonuclease III/*deficiency/genetics/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Brunsell, P. R. ; Maejima, Y. ; Yagi, Y. ; Hirano, Y. ; Shimada, T.

    [S.l.] : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1089-7674
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Edge plasma fluctuations are studied with inserted triple Langmuir probes and magnetic coils in the TPE-1RM20 reversed-field pinch [Y. Yagi et al., in Plasma Physics and Controlled Nuclear Fusion Research 1992 (International Atomic Energy Agency, Vienna, 1993), Vol. 2, p. 611]. Two-point measurements show that density and potential fluctuations have relatively low mode numbers (m〈3, n〈40). High coherence (γ=0.5) with magnetic field fluctuations and similar mode spectra suggest that density and potential fluctuations are mainly caused by electromagnetic turbulence. Broadband magnetic fluctuations are dominated by m=0, low-n modes and internally resonant m=1 and m=2 modes. A coherent (f=20–30 kHz) m=0, low-n mode is also observed. Particle flux driven by electrostatic electric field fluctuations is 50%–100% of total flux obtained from Dα line intensity measurement. Low-frequency fluctuations (f〈100 kHz) give the main contribution to the total flux. Electrostatic fluctuation driven electron energy flux is only of the order of 10% of total nonradiative power loss.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.870627

    Articles: DFG German National Licenses
  6. 6
    Ji, H. ; Prager, S. C. ; Almagri, A. F. ; Sarff, J. S. ; Yagi, Y. ; Hirano, Y. ; Hattori, K. ; Toyama, H.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7674
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A series of detailed experiments has been conducted in three laboratory plasma devices to measure the dynamo electric field along the equilibrium field line (the α effect) arising from the correlation between the fluctuating flow velocity and magnetic field. The fluctuating flow velocity is obtained from probe measurement of the fluctuating E×B drift and electron diamagnetic drift. The three major findings are the following: (1) The α effect accounts for the dynamo current generation, even in the time dependence through a "sawtooth'' cycle; (2) at low collisionality the dynamo is explained primarily by the widely studied pressureless magnetohydrodynamic (MHD) model, i.e., the fluctuating velocity is dominated by the E×B drift; (3) at high collisionality, a new "diamagnetic dynamo'' is observed, in which the fluctuating velocity is dominated by the electron diamagnetic drift. In addition, direct measurements of the helicity flux indicate that the dynamo activity transports magnetic helicity from one part of the plasma to another, but the total helicity is roughly conserved, verifying Taylor's [Phys. Rev. Lett. 33, 1139 (1974); Rev. Mod. Phys. 58, 741 (1986)] conjecture. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.871989

    Articles: DFG German National Licenses
  7. 7
    Hiroyama, Y. ; Motooka, T. ; Suzuki, R. ; Hirano, Y. ; Sato, F.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Hydrogenation effects on the structural relaxation and defect evolution in amorphous silicon (a-Si) prepared by ion implantation and evaporation have been investigated using Raman scattering spectroscopy and positron lifetime measurements. Bond angle deviation Δθ in nonhydrogenated a-Si was significantly reduced due to 300 °C annealing in atomic hydrogen atmosphere. This indicates that the reduction in Δθ of hydrogenated amorphous silicon (a-Si:H) is not only due to relaxation during the deposition process of a-Si:H films as proposed by Jackson et al. [Philos. Mag. B 64, 611 (1991)] but also due to posthydrogenation of nonhydrogenated a-Si. It was also found that agglomeration of vacancy-type defects in evaporated a-Si during 450 °C annealing is enhanced after posthydrogenation, while no remarkable enhancement can be seen in a-Si prepared by ion implantation. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.115799

    Articles: DFG German National Licenses
  8. 8
    Hirano, Y. ; Sato, F. ; Aihara, S. ; Saito, N.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 2001
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Nanometer-sized Si dot multilayers have been prepared by repeating a sequence of low-pressure chemical vapor deposition for dot formation and thermal oxidation for dot isolation. For the multilayer with Si dots in the range of 3–5 nm, the onset of photoconductivity is observable at a photon energy of 2 eV, corresponding to the optical absorption edge of the Si dots. This result indicates that the nanometer-sized Si dot multilayers are promising as photoconductors that work at various wavelengths because the optical band gap can be varied by controlling the dot size. © 2001 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1408600

    Articles: DFG German National Licenses
  9. 9
    Kawakami, Y. ; Hirano, Y. ; Miyashlta, M. ; Fukunaga, T.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1993
    Staff View
    ISSN:
    1600-0838
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Sports Science
    Notes:
    Ten healthy male subjects carried out bilateral concentric leg extension training twice a week for 8 weeks. Before and after the training, maximal voluntary isometric and isokinetic strength and cross-sectional areas of the quadriceps femoris were measured. Maximal bilateral leg extension power increased significantly after the training. Isometric and concentric unilateral strength did not change significantly before and after the training, while eccentric strength at 0.52 and 1.05 rad·s−1 increased after the training with no changes in cross-sectional area. The correlations between strength and cross-sectional area increased significantly after the training. It was speculated that the increase in eccentric strength of knee extensors was due to modification of the neural inhibition during eccentric muscle actions.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0838.1993.tb00356.x

    Articles: DFG German National Licenses
  10. 10
    Brunsell, P. R. ; Yagi, Y. ; Hirano, Y. ; Maejima, Y. ; Shimada, T.

    New York, NY : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7666
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Magnetic field fluctuations have been measured in the TPE-1RM20 reversed-field pinch [in Plasma Physics and Controlled Nuclear Fusion Research, Proceedings of the 14th International Conference, 1992, Würzburg (International Atomic Energy Agency, Vienna, 1992) Paper IAEA-CN-56/C-4-3]. The dominant modes are m=1/n=7–9, resonant near the axis. The fluctuations are coherent, corresponding to nearly continuous rigid body rotation with poloidal and toroidal frequencies of fθ=130–170 kHz and fφ=11–14 kHz, respectively. Discrete dynamo events (in which toroidal magnetic flux is generated) of two different types are observed at high values of pinch parameter (aitch-theta(approximately-greater-than)1.6). The first type is triggered by a single, wall-locked m=1/n=7 mode. The slowing down of the mode rotation is in rough agreement with a simulation which assumes the effect of induced eddy current in the vacuum liner. In the subsequent relaxation event, the locked mode decays and the m=1 spectrum cascades to higher-n modes. However, in some cases the saturated m=1/n=7 mode exists for periods up to t=0.4 msec, resembling single helicity Ohmic states. The second type of event is characterized by phase locking of several m=1/n=7–9 modes and the appearance of large m=0/n=1–5 modes. Mode rotation continues through the event, similar to the normal machine operating condition.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.860939

    Articles: DFG German National Licenses
  11. 11
    Hattori, K. ; Hirano, Y. ; Shimada, T. ; Yagi, Y. ; Maejima, Y. ; Hirota, I. ; Ogawa, K.

    New York, NY : American Institute of Physics (AIP)
    Published 1991
    Staff View
    ISSN:
    1089-7666
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Fluctuations of magnetic fields and related magnetohydrodynamic (MHD) phenomena are investigated in the TPE-1RM15 reversed-field pinch experiment [Plasma Physics and Controlled Fusion Research, 1986 (IAEA, Vienna, 1987), Vol. 2, p. 453]. Mode analysis of fluctuations measured by multichannel coils reveals that nonlinear interactions between m=1 and m=0 modes, such as nonlinear coupling and phase locking, play significant roles during a dynamo event (i.e., the flux genertion process in the sustainment phase), resulting in transition from an unstable state to a stable state. Behaviors of these fluctuations are found to be toroidally asymmetrical due to strong nonlinearity. Study of the current ramping experiment shows that the inverse of global energy confinement time depends on the squared fluctuation level offset linearly, which is consistent with the prediction of the transport model based on the diffusion of stochastic field lines. By examining the dependence of the resistive part of the loop voltage on the fluctuation level, the input power to the electrons and ions are estimated to be about 70% and 30% of the total input power, respectively.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.859791

    Articles: DFG German National Licenses
  12. 12
    Kimura, J. ; Hirano, Y. ; Takemoto, S. ; Nambo, Y. ; Ishinazaka, T. ; Himeno, R. ; Mishima, T. ; Tsumagari, S. ; Yokota, H.

    Berlin, Germany : Blackwell Verlag GmbH
    Published 2005
    Staff View
    ISSN:
    1439-0264
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The equine ovary has a very unique structure in terms of its extreme large size, the presence of the ovulation fossa and the inverted location of its cortex and medulla. In the previous study, it was recognized that the application of three-dimensional internal structure microscopy (3D-ISM) to observe the mare ovary is very effective. Three-dimensional reconstruction of serially sliced images made by 3D-ISM was successful in this study with the aid of the sophisticated image processing technique. The rotation of the reconstructed ovary has been carried out with and without the application of the transparency technique in the ovarian stromal region. The spatial localization of follicles and corpus luteum was clearly visualized by rotating the reconstructed image of the ovary. The extraction of the images of follicles and corpus luteum was also available and gave a quantifiable understanding of their structure.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1439-0264.2004.00567.x

    Articles: DFG German National Licenses
  13. 13
    Sekita, T. ; Minakuchi, S. ; Hirano, Y. ; Kobayashi, K. ; Nagao, M.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2842
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Movements of soft tissues surrounding the oral cavity, especially lips and cheeks, have a strong influence on mastication and phonetics. They also influence the relationship between a denture and its oral environment. The purpose of this study was to develop a three-dimensional measuring system for soft tissue movement. This system consisted of two video trackers placed stereographically and a computer. In addition, one video tracker was connected for measuring mandibular movements. The accuracy of this system was evaluated using computerized XYZ pulse stage. The resolution of this system was 0·10×0·10×0·10 mm, when the measurement was carried out in the area of the 24·0 (X)×20·0 (Y)×20·0 (Z) mm with a working distance of 500 mm and a frequency of 120 Hz. In the present study, the lip movements of a dentulous subject with mandibular movements during chewing peanuts were analysed using this system. The new system demonstrated its value for analysing soft tissue movement.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2842.2000.00616.x

    Articles: DFG German National Licenses
  14. 14
    Miyashita, K. ; Sekita, T. ; Minakuchi, S. ; Hirano, Y. ; Kobayashi, K. ; Nagao, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1998
    Staff View
    ISSN:
    1365-2842
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    SUMMARY The purpose of this study was (1) to assemble and verify a system to measure the three-dimensional (3-D) movement of the upper and lower complete dentures and the movement of the mandible simultaneously, and (2) to analyse the relation between denture movements and the path of closure of the mandible during function. A 3-D motion capture system with four infrared TV cameras was used for this purpose. The relation between the dentures and the mandibular movements was analysed through the change of the inner product of normal vectors of the denture occlusal planes and mandibular planes. The mandibular movements were classified into two types the normal stroke (the path of closure was on the ipsilateral side of mastication) and the reverse stroke (on the contralateral side). The results showed that the system could measure the denture mobility within a 0·3 mm error. The mobility of the upper dentures had a correlation to the path of closure of the mandible regardless of the working side or nonworking side, and the lower dentures had a tendency to move toward the working side.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2842.1998.00273.x

    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    0301-4622
    Keywords:
    Bovine carbonic anhydrase B ; Hydrophobic core ; Hydrophobic fluorescence probe ; Molten-globule state
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0301-4622(91)80021-I

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    0014-5793
    Keywords:
    ATP ; Inositol trisphosphate ; Intracellular calcium ; Neural cell line
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(91)80693-W

    Articles: DFG German National Licenses
  17. 17
    Hiraoka, M. ; Hirano, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-2828
    Keywords:
    Arrhythmias ; Delayed afterdepolarization ; Internal longitudinal resistance ; Membrane resistance
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-2828(86)80043-8

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    0040-4020
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0040-4020(01)85147-4

    Articles: DFG German National Licenses
  19. 19
    Hirano, Y. ; Nagaya, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-460X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-460X(81)80047-8

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-291X(90)91158-O

    Articles: DFG German National Licenses