Search Results - (Author, Cooperation:X. F. Kong)
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1Latest Papers from Table of Contents or Articles in PressD. Bogunovic ; M. Byun ; L. A. Durfee ; A. Abhyankar ; O. Sanal ; D. Mansouri ; S. Salem ; I. Radovanovic ; A. V. Grant ; P. Adimi ; N. Mansouri ; S. Okada ; V. L. Bryant ; X. F. Kong ; A. Kreins ; M. M. Velez ; B. Boisson ; S. Khalilzadeh ; U. Ozcelik ; I. A. Darazam ; J. W. Schoggins ; C. M. Rice ; S. Al-Muhsen ; M. Behr ; G. Vogt ; A. Puel ; J. Bustamante ; P. Gros ; J. M. Huibregtse ; L. Abel ; S. Boisson-Dupuis ; J. L. Casanova
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-08-04Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibodies, Viral/blood ; Cytokines/genetics/*immunology ; Female ; Granulocytes/immunology ; Humans ; Immunity ; Interferon-gamma/*immunology ; Interleukin-12/immunology ; Killer Cells, Natural/immunology ; Male ; Mice ; Mycobacterium Infections/blood/genetics/*immunology ; Pedigree ; T-Lymphocytes/immunology ; Ubiquitins/genetics/*immunology ; Virus Diseases/blood/*immunologyPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1432-0983Keywords: Prokaryotic promoters ; Chloroplast DNA replication origin ; Chlamydomonas reinhardtiiSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary In Chlamydomonas reinhardtii, one displacement loop region which initiates the replication of chloroplast DNA was located on a 1.05 kb restriction fragment. This fragment was cloned and sequenced. In this report, the galK expression plasmid, pK01 was used to screen for the presence of any prokaryotic promoter within the cloned fragment. The insertion of 2 AluI fragments yielded galK+ colonies. Sequence analyses of these Alul inserts revealed prokaryotic promoter consensus regions. Cloning into pKOTWI and subsequent DNA sequencing were used to determine the promoter-active orientation of each insert. Two back-to-back prokaryotic promoters were mapped on a 79 by Alul fragment located within the displacement loop region.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesAlexander-Bridges, M. ; Ercolani, Louis ; Kong, X. F. ; Nasrin, Nargis
New York, N.Y. : Wiley-Blackwell
Published 1992Staff ViewISSN: 0730-2312Keywords: insulin ; gene transcription ; GAPDH ; hormone regulation ; differentiation-dependent gene expression ; Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyChemistry and PharmacologyMedicineNotes: Insulin induces glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene transcription in part by regulating one or more proteins that bind a cis-acting element, IRE-A. We have recently cloned a protein, IRE-ABP, that binds the IRE-A element. IRE-ABP is a member of the HMG class of transcriptional regulators and is 67% identical within its HMG box domain to the candidate gene for the testis-determining factor, SRY. IRE-ABP and SRY share binding specificity for the IRE-A motif. This sequence is also highly conserved with a core motif, 5′-Py-ctttg(a/t)-3′, contained in T-cell specific genes that have high affinity for TCF-1α, another member of the HMG class of transcriptional regulators. Thus, diverse members of the HMG family interact with similar nucleotide sequences to regulate expression of genes that initiate and maintain the differentiated phenotype. We have found this core motif in the upstream region of many genes that are positively and negatively regulated by insulin. These observations suggest that IRE-ABP or a related family member may coordinate the expression of these genes. The HMG family of proteins has diverse functions ranging from the regulation of differentiation and mating type in yeast to the regulation of tissue-and species-specific gene expression in mammals. Insulin regulates GAPDH gene transcription in a tissue-specfic manner. We propose that members of the IRE-ABP family play an important role in controlling tissue specificity of the insulin response.Additional Material: 2 Ill.Type of Medium: Electronic ResourceURL: