Search Results - (Author, Cooperation:X. D. Zhang)

Showing 1 - 20 results of 24, query time: 0.29s Refine Results
  1. 1
    Staff View
    Publication Date:
    2018-03-09
    Publisher:
    American Society of Hematology (ASH)
    Print ISSN:
    0006-4971
    Electronic ISSN:
    1528-0020
    Topics:
    Biology
    Medicine
    Keywords:
    Red Cells, Iron, and Erythropoiesis
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-08-31
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1755-1307
    Electronic ISSN:
    1755-1315
    Topics:
    Geography
    Geosciences
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
  4. 4
    Staff View
    Publication Date:
    2016-01-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Animals, Genetically Modified ; Anxiety/genetics/psychology ; Autistic Disorder/*genetics/metabolism/physiopathology/*psychology ; Brain/metabolism ; Cognition/physiology ; *Disease Models, Animal ; Female ; Germ-Line Mutation/*genetics ; Heredity/*genetics ; Humans ; Locomotion/genetics/physiology ; Macaca fascicularis ; Male ; Methyl-CpG-Binding Protein 2/*genetics/*metabolism ; Phenotype ; Social Behavior ; Sperm Injections, Intracytoplasmic ; Transgenes/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    genomics, bioinformatics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2011-02-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Actins/chemistry/*metabolism ; Animals ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cell Line ; *Gene Expression Regulation/drug effects ; Gene Knockdown Techniques ; HeLa Cells ; Homeostasis/genetics ; Humans ; Inflammation/*genetics ; Lipopolysaccharides/pharmacology ; Mice ; Microfilament Proteins/chemistry/deficiency/genetics/*metabolism ; Orphan Nuclear Receptors/metabolism ; Peptide Hydrolases/metabolism ; Peritonitis/chemically induced/metabolism ; Phosphorylation ; Promoter Regions, Genetic/genetics ; Protein Structure, Tertiary ; Signal Transduction ; Sumoylation ; Thioglycolates/pharmacology ; Toll-Like Receptors/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Zhang, X. D. ; Zhang, Y. Z. ; Mahajan, S. M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1089-7674
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A perturbation theory based on the two-dimensional (2-D) ballooning transform is systematically developed for ideal toroidal Alfvén eigenmodes (TAEs). A formula, similar to the Fermi golden rule for decaying systems in quantum mechanics, is derived for the continuum damping rate of the TAE; the decay (damping) rate is expressed explicitly in terms of the coupling of the TAE to the continuum spectrum. Numerical results are compared with previous calculations. It is found that in some narrow intervals of the parameter mεˆ, the damping rate varies very rapidly. These regions correspond precisely to the root missing intervals of the numerical solution by Rosenbluth et al. [Phys. Fluids B 4, 2189 (1992)].
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Zhang, X.-D. ; Lötvalt, J. ; Arakawa, H. ; Welinder, H. ; Skerfving, S.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1998
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Organic acid anhydrides (OAAs) are industrial chemicals that may cause induction of specific IgE and airway symptoms in exposed workers. They are a good model for studies of relationships between chemical structure and the sensitizing potential of reactive low-molecular-weight compounds. Hexahydrophthalic anhydride (HHPA) is such a compound. This study aimed to evaluate the relationship between specific IgG1 levels and airway responses in a model to predict the sensitizing potential of OAAs. Guinea pigs were either actively or passively sensitized to HHPA. For active sensitization, guinea pigs were injected i.d. with 0.1 ml of olive oil (vehicle) or 0.05, 0.5, or 5% HHPA in olive oil. Passive sensitization was performed by i.p. injection of different volumes of antisera (0.75–6 ml, either unheated to keep IgE or heated to destroy IgE) taken form HHPA-sensitized guinea pigs. Specific antibody levels were evaluated with ELISA and passive cutaneous anaphylaxis. Animals were challenged 16–18 days after active sensitization, or 2 days after passive sensitization, by interatracheal instillation with HHPA conjungated to guinea pig serum albumin (HHPA-GPSA; 0.05% in saline), and the immediate effects on lung resistance (R1), and plasma extravasation, measured as Evans blue dye extravasation, for up to 6 min were recorded. Active sensitization caused production of specific IgG1. Provocation with HHPA-GPSA caused an increase of both (R1), and Evans blue dye extravasation, which was dependent upon the active sensitization dose. Challenge with HHPA-GPSA in passively sensitized guinea pigs also produced an increase in both (R1), and Evans blue dy extravasation which was related to IgG1 level. In the guinea pig model of HHPA-induced airway allergy, the airway responses are closely related to the serum levels of specific IgG1. Thus, the IgG1 levels induced by the immunization may reflect the sensitizing potential of HHPA.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Zhang, Y. Z. ; Mahajan, S. M. ; Zhang, X. D.

    New York, NY : American Institute of Physics (AIP)
    Published 1992
    Staff View
    ISSN:
    1089-7666
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    By systematically doing the higher-order theory, the predictions of the conventional ballooning theory (CBT) are examined for nonideal systems. For the complex solvability condition to be satisfied, radial variation of the lowest-order mode amplitude needs to be invoked. It turns out, however, that even this procedure with its concomitant modifications of eigenvalues and eigenstructures, is not sufficient to justify the predictions of many CBT solutions; only a small set of the CBT solutions could be put on firm footing. To demonstrate this work's general conclusions, theoretical and numerical results are presented for a system of fluid drift waves with nonadiabatic electron response.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Zhang, X. D. ; Zhang, Y. Z. ; Mahajan, S. M.

    New York, NY : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7666
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The stability of kinetic toroidal Alfvén waves with multigap coupling is analyzed by using the two-dimensional ballooning transform. An alternate convergence scheme, based on the smallness of the inverse aspect ratio, is devised. The resulting wave functions are oscillatory and do not balloon in contrast to the wave functions of conventional ballooning theory. It is shown that the single-gap theory is a special, weak shear (s→0) limit of the formalism. Analytical and numerical results for the two fundamental branches, the ideal toroidal Alfvén eigenmode (TAE), and the kinetic toroidal Alfvén eigenmode (KTAE), are presented and discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Zhang, X. D. ; Murray, D. K. ; Lewis, D. M. ; Siegel, P. D.

    Oxford, UK : Munksgaard International Publishers
    Published 2002
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background: Trimellitic anhydride (TMA)-induced occupational asthma is thought to be associated with its ability to acylate proteins and to induce production of TMA-specific immunoglobulin (Ig)E. Though the respiratory tract is considered to be a major exposure route leading to airway sensitization, the potential role of dermal exposure producing asthmatic sensitization is not known. The present study examines the ability of dry TMA powder to sensitize Brown Norway rats when applied, topically, to the skin.Methods: A patch of hair was carefully clipped with scissors on the rat's back. Dry TMA powder (0.3, 1.25, 5 and 20 mg) was administered on days 0, 7, 14 and 21, and the area occluded with surgical tape overnight after each application. Residual powder recovered from the occluded skin was analyzed by proton nuclear magnetic resonance and was still predominantly TMA. Circulating anti-TMA IgE and IgG were measured by ELISA.Results: TMA elicited dose-dependent production of specific IgE and IgG. Specific antibodies were detectable 2 weeks after the first TMA exposure and peaked between 3 and 4 weeks.Conclusion: The data suggest that topical skin exposure to dry TMA powder can induce allergic/immunological sensitization as demonstrated by the production of specific antibodies.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Zhao, H. ; Zhang, X.-D. ; Welinder, H. ; Jonson, B.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1997
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    We established a guinea-pig model of anaphylactic bronchoconstriction provoked in immunized animals by inhalation and intravenous administration of 4,4-methyltetrahydrophthalic anhydride (MTHPA) and hexahydrophthalic anhydride (HHPA). Guinea pigs were immunized intradermally with either MTHPA (n= 8) or HHPA (n= 8) suspended in olive oil. Control animals (n= 8) were injected with olive oil alone. After 4 weeks, the animals were challenged during mechanical ventilation by inhalation or intravenous administration of MTHPA or HHPA conjugated with guinea-pig serum albumin (GPSA). Airway flow, and airway and esophageal pressures were measured. Resistance (R) and static compliance (Cst) of the respiratory system (rs), lung (1), and chest wall were studied with the flow-interruption technique. After challenge with MTHPA-GPSA or HHPA-GPSA, R, rs and R, 1 increased dramatically while Cst, rs and Cst,1 decreased, and severe arterial hypoxia developed. The reaction occurred at a well-defined dose of anhydride and lasted about 30 min. When the same dose was repeated after 30 min, the response was much attenuated. MTHPA and HHPA can induce asthma in guinea pigs. The dose-response curve at antigen challenge is steep. Once a threshold dose is reached, a severe reaction occurs. The reactivity is then exhausted. This model may be suitable for assessing occupational asthma caused by acid anhydrides and possibly by other low-molecular-weight chemicals.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0038-1098
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Yang, Y.-c. ; Zhang, X.-d. ; Kong, L.-s. ; Pan, Q. ; Ge, S.-l.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0038-1098
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    0038-1098
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Flavell, J.H. ; Zhang, X.-D. ; Zou, H. ; Dong, Q. ; Qi, S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0010-0285
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Yang, Y.-c. ; Zhang, X.-d. ; Pan, Q. ; Kong, L.-S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0304-8853
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Mao, S.-Z. ; Zhang, X.-D. ; Dereppe, J.-M. ; Du, Y.-R.
    Springer
    Published 2000
    Staff View
    ISSN:
    1435-1536
    Keywords:
    Key words Polyacrylamide ; Nuclear magnetic resonance ; Relaxation ; Cohesional entanglement
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract  The cohesive interaction among polymer chains in a polyacrylamide (PAAm)–D2O solution has been studied by NMR relaxation. The NMR relaxation times of PAAm in the good solvent D2O were measured at different temperatures. The results show that the solution system has a high local viscosity and that its relaxation characteristic is soft-solid-like. The temperature dependence of the relaxation behavior of the solution is obviously different from that of ordinary polymer solutions. The difference lies in the relaxation behavior of the methylene protons in the main chain of PAAm, as shown by analyzing the relaxation process with single exponential and biexponential decays. As the temperature increases, the solvation is weakened, leading polymer chains to form curling coils, thus hindering the movement of the methylene protons among the main chains. It can be expected from the existence of 80% fast-relaxing protons that there are a zhigh number of entanglements among the polymer chains in PAAm solution. The information about entanglements among the polymer chains can be deduced from the biexponential dependence of the spin–spin relaxation on the concentration of the polymer solutions.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    0040-6090
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Weng, J. ; Wolke, J. G. C. ; Zhang, X. D. ; Groot, K.
    Springer
    Published 1996
    Staff View
    ISSN:
    1573-4811
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses