Search Results - (Author, Cooperation:W. Y. Langdon)
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1M. Paolino ; A. Choidas ; S. Wallner ; B. Pranjic ; I. Uribesalgo ; S. Loeser ; A. M. Jamieson ; W. Y. Langdon ; F. Ikeda ; J. P. Fededa ; S. J. Cronin ; R. Nitsch ; C. Schultz-Fademrecht ; J. Eickhoff ; S. Menninger ; A. Unger ; R. Torka ; T. Gruber ; R. Hinterleitner ; G. Baier ; D. Wolf ; A. Ullrich ; B. M. Klebl ; J. M. Penninger
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-02-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/deficiency/genetics/*metabolism ; Animals ; Anticoagulants/pharmacology/therapeutic use ; Female ; Killer Cells, Natural/drug effects/*immunology/metabolism ; Male ; Mammary Neoplasms, Experimental/drug therapy/genetics/immunology/*pathology ; Melanoma, Experimental/drug therapy/genetics/immunology/*pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Neoplasm Metastasis/drug therapy/*immunology/prevention & control ; Proto-Oncogene Proteins/antagonists & inhibitors/metabolism ; Proto-Oncogene Proteins c-cbl/deficiency/genetics/*metabolism ; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors/*metabolism ; Ubiquitin-Protein Ligases/deficiency/genetics/*metabolism ; Ubiquitination ; Warfarin/pharmacology/therapeutic usePublished by: -
2Langdon, W. Y. ; McKenzie, I. F. C. ; Shellam, G.R.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1744-313XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Murine alloantisera to lymphocyte (Ly) alloantigens also contain antibodies to murine leukaemia viruses (MuLV) in high titre. A number of such sera were extensively absorbed with ecotropic AKR murine leukaemia virus to remove contaqiminating anti-MuLV antibodies. The virus-absorbed and unabsorbed antisera wre then examined by the radioimmune precipitation (RIP) assay for anti-MuLV antibodies, and for anti-Ly antibodies by cytotoxicity assays against specific target cells. The results presented here demonstrate that whilst virus absorption markdely reduced the anti-viraql titres of the alloantisera they ahd no effect on the anti-Ly titres of any of them. This indicated that none of the Ly antigens which was examined cross reacts with the antigens of ecotropic AKR-MuLV and further suggest that Ly antigens are not encoded by the genes of endogenous ecotropic MuLVs. It was also demonstrated that the majority of the constaninating anti-MuLV antibodies present in anti-Ly-6.2 proteins of the virus.Type of Medium: Electronic ResourceURL: -
3Jones, C. ; Penny, L. ; Mattina, T. ; Yu, S. ; Baker, E. ; Voullaire, L. ; Langdon, W. Y. ; Sutherland, G. R. ; Richards, R. I. ; Tunnacliffe, A.
[s.l.] : Nature Publishing Group
Published 1995Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The fragile site FRA11B has been localized to the p(CCG)n repeat of the CBL2 proto-oncogene. A proportion of Jacobsen (11q−) syndrome patients inherited a chromosome carrying a CBL2 p(CCG)n expansion, which was truncated close to FRA11B. ...Type of Medium: Electronic ResourceURL: