Search Results - (Author, Cooperation:W. X. Yan)
-
1M. Tabebordbar ; K. Zhu ; J. K. Cheng ; W. L. Chew ; J. J. Widrick ; W. X. Yan ; C. Maesner ; E. Y. Wu ; R. Xiao ; F. A. Ran ; L. Cong ; F. Zhang ; L. H. Vandenberghe ; G. M. Church ; A. J. Wagers
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats ; Dependovirus ; Disease Models, Animal ; Exons ; Frameshift Mutation ; Genetic Therapy/*methods ; Mice ; Mice, Inbred mdx ; Muscle, Skeletal/metabolism ; Muscular Dystrophy, Duchenne/genetics/*therapy ; Myocardium/metabolism ; RNA, Messenger/genetics ; Satellite Cells, Skeletal Muscle/*metabolism ; Sequence Deletion ; Transduction, Genetic/*methodsPublished by: -
2C. E. Nelson ; C. H. Hakim ; D. G. Ousterout ; P. I. Thakore ; E. A. Moreb ; R. M. Castellanos Rivera ; S. Madhavan ; X. Pan ; F. A. Ran ; W. X. Yan ; A. Asokan ; F. Zhang ; D. Duan ; C. A. Gersbach
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats ; Dependovirus ; Disease Models, Animal ; Dystrophin/*genetics ; Exons/*genetics ; Genetic Therapy/*methods ; Male ; Mice ; Mice, Inbred mdx ; Muscle, Skeletal/*metabolism ; Muscular Dystrophy, Duchenne/genetics/*therapy ; Sequence DeletionPublished by: -
3I. M. Slaymaker ; L. Gao ; B. Zetsche ; D. A. Scott ; W. X. Yan ; F. Zhang
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-12-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Bacterial Proteins/*chemistry/genetics ; *DNA Cleavage ; Endonucleases/*chemistry/genetics ; Humans ; Mutagenesis ; Point Mutation ; Protein Conformation ; *Protein Engineering ; RNA, Guide/genetics ; Streptococcus pyogenes/*enzymologyPublished by: -
4F. A. Ran ; L. Cong ; W. X. Yan ; D. A. Scott ; J. S. Gootenberg ; A. J. Kriz ; B. Zetsche ; O. Shalem ; X. Wu ; K. S. Makarova ; E. V. Koonin ; P. A. Sharp ; F. Zhang
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Base Sequence ; CRISPR-Associated Proteins/genetics/*metabolism ; Cholesterol/blood/metabolism ; Gene Targeting ; Genetic Engineering/*methods ; Genome/*genetics ; Liver/metabolism/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Proprotein Convertases/biosynthesis/blood/deficiency/genetics ; Serine Endopeptidases/biosynthesis/blood/deficiency/genetics ; Staphylococcus aureus/*enzymology/genetics ; Substrate SpecificityPublished by: