Search Results - (Author, Cooperation:W. S. Trimble)
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1Latest Papers from Table of Contents or Articles in PressA. Y. Lee ; R. P. St Onge ; M. J. Proctor ; I. M. Wallace ; A. H. Nile ; P. A. Spagnuolo ; Y. Jitkova ; M. Gronda ; Y. Wu ; M. K. Kim ; K. Cheung-Ong ; N. P. Torres ; E. D. Spear ; M. K. Han ; U. Schlecht ; S. Suresh ; G. Duby ; L. E. Heisler ; A. Surendra ; E. Fung ; M. L. Urbanus ; M. Gebbia ; E. Lissina ; M. Miranda ; J. H. Chiang ; A. M. Aparicio ; M. Zeghouf ; R. W. Davis ; J. Cherfils ; M. Boutry ; C. A. Kaiser ; C. L. Cummins ; W. S. Trimble ; G. W. Brown ; A. D. Schimmer ; V. A. Bankaitis ; C. Nislow ; G. D. Bader ; G. Giaever
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-04-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Cells/*drug effects ; Drug Evaluation, Preclinical/*methods ; Drug Resistance/*genetics ; *Gene Regulatory Networks ; Genome-Wide Association Study/*methods ; Haploinsufficiency ; Humans ; Pharmacogenetics ; Saccharomyces cerevisiae/drug effects/genetics ; Small Molecule Libraries/*pharmacologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressD. Neculai ; M. Schwake ; M. Ravichandran ; F. Zunke ; R. F. Collins ; J. Peters ; M. Neculai ; J. Plumb ; P. Loppnau ; J. C. Pizarro ; A. Seitova ; W. S. Trimble ; P. Saftig ; S. Grinstein ; S. Dhe-Paganon
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-10-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, CD36/*metabolism ; CHO Cells ; Cricetulus ; HeLa Cells ; Humans ; Lysosome-Associated Membrane Glycoproteins/*chemistry/metabolism ; *Models, Molecular ; Protein Binding ; Protein Structure, TertiaryPublished by: -
3Articles: DFG German National LicensesTrimble, W. S. ; Johnson, P. W. ; Hozumi, N. ; Roder, J. C.
[s.l.] : Nature Publishing Group
Published 1986Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] To examine the NK sensitivity of cells during the transformation process, we have constructed vectors that permit controlled expression of c-Ha-ras (Fig. 1). For constitutive expression of ras in fibroblast cells, a 6.6-kilobase (kb) BamHl fragment containing the transforming human c-Ha-ras gene3 ...Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesTrimble, W. S. ; Baker, M. D. ; Boulianne, G. L. ; Murialdo, H. ; Hozumi, N. ; Shulman, M. J.
Springer
Published 1986Staff ViewISSN: 1572-9931Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Hybridoma mutants defective in the expression of IgM have been analyzed by molecular and somatic cell hybridization techniques. The frequency of κ light-chain mutants in the hybridoma PC7 was much higher than for other cell lines. In contrast to the mutations which we observed previously, the κ mutants examined here resulted from complete or partial deletion of the κ gene. Mutants defective in μ chain synthesis were of more diverse types including deletions, gross rearrangements, and more subtle changes. One mutant containing acis -acting mutation resulting in reduced expression of the μ chain had an associated partial duplication of the μ gene, while others making low or undetectable levels of μ had no gross alterations in genetic structure. The usefulness of this approach to the study of gene structure and expression is discussed.Type of Medium: Electronic ResourceURL: