Search Results - (Author, Cooperation:W. Hagen)
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1A. von Appen ; J. Kosinski ; L. Sparks ; A. Ori ; A. L. DiGuilio ; B. Vollmer ; M. T. Mackmull ; N. Banterle ; L. Parca ; P. Kastritis ; K. Buczak ; S. Mosalaganti ; W. Hagen ; A. Andres-Pons ; E. A. Lemke ; P. Bork ; W. Antonin ; J. S. Glavy ; K. H. Bui ; M. Beck
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-09-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Binding Sites ; *Cryoelectron Microscopy ; HeLa Cells ; Humans ; Mass Spectrometry ; Models, Molecular ; Molecular Chaperones/chemistry/metabolism/ultrastructure ; Nuclear Envelope/metabolism ; Nuclear Pore/*chemistry/metabolism/*ultrastructure ; Nuclear Pore Complex Proteins/*chemistry/metabolism/*ultrastructure ; Protein Conformation ; Protein Multimerization ; Protein StabilityPublished by: -
2David Kuhness, Hyun Jin Yang, Hagen W. Klemm, Mauricio Prieto, Gina Peschel, Alexander Fuhrich, Dietrich Menzel, Thomas Schmidt, Xin Yu, Shamil Shaikhutdinov, Adrian Lewandowski, Markus Heyde, Anna Kelemen, Radoslaw Wlodarczyk, Denis Usvyat, Martin Schütz, Joachim Sauer, Hans-Joachim Freund
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-05-03Publisher: American Chemical Society (ACS)Print ISSN: 0002-7863Electronic ISSN: 1520-5126Topics: Chemistry and PharmacologyPublished by: -
3Staff View
ISSN: 0266-3554Topics: HistoryNotes: BOOK REVIEWSURL: -
4Staff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0022-0981Keywords: Alcohol ; Arctic ; Copepod ; Fatty acid ; Feeding ; Lipid ; Trophic markerSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0022-2860Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0584-8539Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0584-8539Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0301-0104Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1438-3888Source: Springer Online Journal Archives 1860-2000Topics: BiologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1572-946XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Laboratory and theoretical studies have been made of the effects of ultraviolet photolysis of interstellar grain mantles which consist of combinations of hydrogen, oxygen, carbon and nitrogen — ‘dirty ice’. It is shown that processes involving photolysis (photoprocessing) of interstellar grains are important during most of their lifetime even including the time they spend in dense clouds. A laboratory designed to simulate the interstellar conditions is described. This is the first time such a laboratory has been able to provide results which may be directly scaled to the astrophysical situations involving interstellar grains and their environment. The evolution of grain analogs is followed by observing the infrared absorption spectra of photolyzed samples of ices deposited at 10 K. The creation and storage of radicals and the production of molecules occur as a result of reactions within the solid. A large number of molecules and radicals observed in the interstellar gas appear in the irradiated ices. Energy released during warm-up is seen from visible luminescence and inferred from vapor pressure enhancement which occurs during warming of photolyzed samples relative to unphotolyzed samples. The evolution of a grain and its role as a source as well as a sink of molecules is pictured as a statistical process within dense clouds. The gradual accretion on and photolysis of an individual grain provides the stored chemical energy the release of which is sporadically triggered by relatively mild events (such as low velocity grain-grain collisions) to produce the impulsive heating needed to eject or evaporate a portion of the grain mantle. An extremely complex and rather refractory substance possessing the infrared signatures of amino groups and carboxylic acid groups and having a maximum mass of 514 amu has been produced at a rate corresponding to a mass conversion rate of interstellar grains of between 2% and 20% in 107 yr. The shape and position of the astronomically observed 3.1 μm band is duplicated in the laboratory and is shown to be a natural consequence of the processing of grain mantles.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1438-2385Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyDescription / Table of Contents: Zusammenfassung In 99 Weinen wurde der Gehalt anl(+)- undd(−)-Lactat enzymatisch bestimmt. Die in der Literatur vorgeschlagene alkalische Verseifung des Weins darf nicht durchgeführt werden, da dies zu stark fehlerhaften Ergebnissen durch die Bildung von Milchsäure aus dem Restzucker der Weine führt. Auf einen Aufschluß durch Säure oder durch Kochen kann verzichtet werden, da die gebundene Menge an Milchsäure im Wein nur zu maximal 100–200 mg/l festgestellt wurde. Wenn nur der Gesamtlactatgehalt interessiert, so kann dieser ebenfalls enzymatisch ohne Differenzierung in die stereoisomeren Formen direkt bestimmt werden. Die Fehlerbreite der Methode ist gering; es besteht eine gute Übereinstimmung mit der chemischen Methode von Rebelein. Bei den untersuchten Weinen variiert bei einem Gesamt-Milchsäuregehalt von 0,10–5,61 g/l der Gehalt an L-Lactat zwischen 0,00 und 4,82 g/l, der Gehalt an D-Lactat zwischen 0,05 und 0,84 g/l. Bei niedrigen Gesamt-Milchsäuregehalten von weniger als 0,6 g/1 kann sowohld-Lactat als auchl-Lactat überwiegen. Je höher die Gesamt-Milchsäuregehalte ansteigen, desto mehr überwiegt dasl-Lactat, dessen Anteil bei Gesamt-Milchsäuregehalten von über 2 g/1 mehr als 80 bzw. 90% des Gesamtlactats beträgt.Notes: Summary Contents ofl(+)- andd(−)-lactic acid in 99 wines have been determined enzymatically. Alkaline hydrolysis of the wines, as proposed in the literature, should not be carried out, because erronious results are hereby obtained, due to the formation of lactic acid from the residual sugars of the wines. Acidic hydrolysis or heating may be dropped because the amounts of esterified lactic acid in wines have been ascertained to be only 100–200 mg/l (max.). If just interested in total lactic acid, disregarding any differentiation of stereoisomeres, then total lactic acid can also be directly determined enzymatically. The method only has a slight marginal error and the results are in good agreement with the chemical method by Rebelein. The content of total lactic acid varies from 0,10–5,61 g/1; ofl-lactic acid from 0,00–4,82 g/l and ofd-lactic acid from 0,05–0,84 g/l. In wines with very low content of total lactic acid (〈 0,6 g/l),d-lactic acid as well as L-lactic acid may be the dominent isomere. However, the higher the content of total lactic acid the more pronounced the content Ofl-lactic acid is. In wines containing more than 2 g/l of total lactic acid, more than 80-90% are taken up byl-lactic acid.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1432-1440Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 1432-2307Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
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ISSN: 1432-2056Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Mesozooplankton collected during five summer expeditions to the Arctic Ocean between 1987 and 1991 was analysed for regional patterns in biomass and species distribution, distinguishing between an epipelagic (0–100 m) and a deeper (0–500 m) layer. A total of 58 stations was sampled mainly in the Nansen, Amundsen and Makarov Basins of the central Arctic Ocean and in areas of the Greenland Sea, West Spitsbergen Current and Barents Sea. Results from the different expeditions were combined to create a transect extending from the Fram Strait across the Eurasian Basin into the Makarov Basin. Mesozooplankton dry mass in the upper 500 m decreased from 8.4 g m−2 in the West Spitsbergen Current to less than 2 g m−2 in the high-Arctic deep-sea basins. In the central Arctic Ocean, biomass was concentrated in the upper 100 m and was dominated by the large copepods Calanus hyperboreus and C. glacialis. In contrast, the mesozooplankton in the West Spitsbergen Current was more evenly distributed throughout the upper 500 m, with C. finmarchicus as the prevailing species. The distribution of abundant mesopelagic species reflected the hydrographic regime: the calanoid copepod Gaetanus tenuispinus and the hyperiid amphipod Themisto abyssorum were most abundant in the Atlantic inflow, while Scaphocalanus magnus was a typical component of the high-Arctic fauna. The relatively high mesozooplankton biomass and the occurrence of boreal-Atlantic species in the central Arctic Ocean are indicators for the import of organic material from allochthonous sources, especially from the northern North Atlantic. Hence, in spite of its enclosure by land masses, the Arctic Ocean is characterized by an exchange of water masses and organisms with the North Atlantic, and advection processes strongly influence the distribution of plankton species in this high-latitude ecosystem.Type of Medium: Electronic ResourceURL: