Search Results - (Author, Cooperation:W. D. Richardson)
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1H. H. Tsai ; H. Li ; L. C. Fuentealba ; A. V. Molofsky ; R. Taveira-Marques ; H. Zhuang ; A. Tenney ; A. T. Murnen ; S. P. Fancy ; F. Merkle ; N. Kessaris ; A. Alvarez-Buylla ; W. D. Richardson ; D. H. Rowitch
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-06-30Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Astrocytes/*physiology ; Bacterial Proteins/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Brain/abnormalities/*cytology/physiology ; Brain Injuries/physiopathology ; *Cell Movement ; Green Fluorescent Proteins ; Homeodomain Proteins/metabolism ; Integrases/genetics ; Luminescent Proteins/metabolism ; Mice ; Mice, Transgenic ; Motor Neurons/*physiology ; Nerve Tissue Proteins/genetics ; Proteins/metabolism ; RNA, Untranslated ; Spinal Cord/abnormalities/*cytology/physiology ; Spinal Cord Injuries/physiopathology ; Synapses/*physiology ; Transcription Factors/metabolism ; Transcription, GeneticPublished by: -
2I. A. McKenzie ; D. Ohayon ; H. Li ; J. P. de Faria ; B. Emery ; K. Tohyama ; W. D. Richardson
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-10-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Brain/*cytology/metabolism ; *Cell Proliferation ; Gene Deletion ; Humans ; *Learning ; Male ; Mental Recall ; Mice ; Mice, Transgenic ; Motor Skills/*physiology ; Myelin Sheath/genetics/*metabolism ; Oligodendroglia/cytology/metabolism/*physiology ; Synaptic Transmission ; Transcription Factors/genetics/metabolismPublished by: -
3PRINGLE, N. ; COLLARINI, E. J. ; HART, I. K. ; RAFF, M. C. ; RICHARDSON, W. D.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
4Eccleston, P. A. ; Collarini, E. J. ; Jessen, K. R. ; Mirsky, R. ; Richardson, W. D.
Oxford, UK : Blackwell Publishing Ltd
Published 1990Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We have investigated the influence of platelet-derived growth factor (PDGF) in peripheral nervous system gliogenesis using two types of Schwann cell cultures. Short-term Schwann cell cultures grow very slowly, but when maintained in culture for several months the division rate of some cells increases, and cell lines can be established. We show that Schwann cells in both short- and long-term culture possess PDGF receptors and synthesize DNA in response to PDGF. Competitive binding experiments show that Schwann cells express mainly PDGF β-receptors and respond better to PDGF-BB than to PDGF-AA. Conditioned media from short-and long-term Schwann cell cultures contain PDGF-like mitogenic activity, and anti-PDGF immunoglobin partially inhibits DNA synthesis in long-term Schwann cell cultures. Antibody neutralization experiments and Northern blot analyses both indicate that the predominant PDGF isoform in these cultures is PDGF-BB. PDGF-like activity is also detected in extracts of rat sciatic nerve. Taken together, these results suggest that PDGF-BB may stimulate Schwann cell proliferation in an autocrine manner during normal development.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1618-2650Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
6Ellis, R. H. ; Hall, E. M. ; Richardson, W. D. ; Vaubel, W. ; Ingle, H. ; Morin, E.
Springer
Published 1929Staff ViewISSN: 1618-2650Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: