Search Results - (Author, Cooperation:W. Coppieters)
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1Latest Papers from Table of Contents or Articles in PressK. Durkin ; W. Coppieters ; C. Drogemuller ; N. Ahariz ; N. Cambisano ; T. Druet ; C. Fasquelle ; A. Haile ; P. Horin ; L. Huang ; Y. Kamatani ; L. Karim ; M. Lathrop ; S. Moser ; K. Oldenbroek ; S. Rieder ; A. Sartelet ; J. Solkner ; H. Stalhammar ; D. Zelenika ; Z. Zhang ; T. Leeb ; M. Georges ; C. Charlier
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-02-03Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Cattle/classification/*genetics ; Chromosome Mapping ; Chromosomes, Mammalian/*genetics ; DNA Copy Number Variations/genetics ; Gene Duplication/genetics ; Gene Fusion/genetics ; Genome-Wide Association Study ; Genotype ; Hair Color/*genetics ; In Situ Hybridization, Fluorescence ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Translocation, Genetic/*geneticsPublished by: -
2Articles: DFG German National LicensesVan De Weghe, A. ; Coppieters, W. ; Bauw, G. ; Vandekerckhove, J. ; Bouquet, Y.
Amsterdam : ElsevierStaff ViewISSN: 0305-0491Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesArchibald, A. L. ; Haley, C. S. ; Brown, J. F. ; Couperwhite, S. ; McQueen, H. A. ; Nicholson, D. ; Coppieters, W. ; Weghe, A. ; Stratil, A. ; Winterø, A. K. ; Fredholm, M. ; Larsen, N. J. ; Nielsen, V. H. ; Milan, D. ; Woloszyn, N. ; Robic, A. ; Dalens, M. ; Riquet, J. ; Gellin, J. ; Caritez, J. -C. ; Burgaud, G. ; Ollivier, L. ; Bidanel, J. -P. ; Vaiman, M. ; Renard, C.
Springer
Published 1995Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract A linkage map of the porcine genome has been developed by segregation analysis of 239 genetic markers. Eighty-one of these markers correspond to known genes. Linkage groups have been assigned to all 18 autosomes plus the X Chromosome (Chr). As 69 of the markers on the linkage map have also been mapped physically (by others), there is significant integration of linkage and physical map data. Six informative markers failed to show linkage to these maps. As in other species, the genetic map of the heterogametic sex (male) was significantly shorter (∼16.5 Morgans) than the genetic map of the homogametic sex (female) (∼21.5 Morgans). The sex-averaged genetic map of the pig was estimated to be ∼18 Morgans in length. Mapping information for 61 Type I loci (genes) enhances the contribution of the pig gene map to comparative gene mapping. Because the linkage map incorporates both highly polymorphic Type II loci, predominantly microsatellites, and Type I loci, it will be useful both for large experiments to map quantitative trait loci and for the subsequent isolation of trait genes following a comparative and candidate gene approach.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesCharlier, C. ; Denys, B. ; Belanche, J.I. ; Coppieters, W. ; Grobet, L. ; Mni, M. ; Womack, J. ; Hanset, R. ; Georges, M.
Springer
Published 1996Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. In the Belgian Blue Cattle breed, coat color variation is mainly under the influence of a single autosomal locus, the roan locus, characterized by a pair of codominant alleles: r + (black) and R (white). Heterozygous r + R animals have intermingled black and white hairs, yielding the ``blue'' phenotype typical of the breed. Major interest for the roan locus stems from its pleiotropic effect on fertility, owing to the critical role of the R allele in the determinism of White Heifer Disease. We describe the linkage mapping of the roan locus to bovine Chromosome (Chr) 5, in the interval between microsatellite markers BPI and AGLA293, with an associated lodscore of 11.2. Moreover, we map a candidate gene, the Steel locus coding for the mast cell growth factor, to bovine Chr 5.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesCoppieters, W. ; Zijlstra, C. ; Weghe, A. ; Bosma, A. A. ; Peelman, L. ; Zeveren, A. ; Bouquet, Y.
Springer
Published 1994Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesCharlier, C. ; Coppieters, W. ; Farnir, F. ; Grobet, L. ; Leroy, P. L. ; Michaux, C. ; Mni, M. ; Schwers, A. ; Vanmanshoven, P. ; Hanset, R. ; Georges, M.
Springer
Published 1995Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract While the hereditary nature of the “double-muscling” phenotype (a generalized muscular hypertrophy documented in several cattle breeds) is well established, its precise segregation mode has remained controversial. Both monogenic models (autosomal dominant or recessive) and oligogenic models have been proposed. Using a panel of 213 bovine microsatellite markers, and an experimental pedigree obtained by backcrossing “double-muscled (Belgian Blue)xconventional (Friesian)” F1 dams to double-muscled sire, we have mapped a locus on bovine Chromosome (Chr) 2 that accounts for all the phenotypic variance in the backcross generation. This locus, referred to as mh (muscular hypertrophy), has been positioned with respect to a map composed of seven Chr 2-specific microsatellites, at 2 cM from the closest marker. This result confirms the validity in the Belgian Blue population of the monogenic model involving an autosomal mh locus, characterized by a wild-type “+” and a recessive “mh” allele, causing the double-muscling phenotype in the homozygous condition. The linkage relationship between the mh locus and the Chr 2 markers was confirmed in three informative pedigrees collected from the general Belgian Blue Cattle population, reinforcing the notion of genetic homogeneity of the double-muscling trait in this breed. This work paves the way towards marker-assisted selection for or against the double-muscling trait, and towards positional cloning of the corresponding gene.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesMusilová, P. ; Lahbib-Mansais, Y. ; Yerle, M. ; Čepical, S. ; Stratil, A. ; Coppieters, W. ; Rubeš, J.
Springer
Published 1995Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesJohansson, M. ; Ellegren, H. ; Marklund, L. ; Coppieters, W. ; Andersson, L.
Springer
Published 1994Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Linkage maps of porcine Chromosomes (Chrs) 3, 6, and 9, based on 31 polymorphic markers, are reported. The markers include 14 microsatellites, 12 RFLPs, three protein polymorphisms, and two blood group loci. The genetic interpretations of 11 RFLPs are documented. The markers were scored in a three-generation Wild Boar/Large White pedigree, and genetic maps were constructed on the basis of two-point and multi-point linkage analysis. Altogether the maps span a genetic distance of 216 cM, and previous physical assignments indicate that the linkage groups cover major parts of the three chromosomes. Significant differences in recombination rates between the sexes were observed for all three chromosomes. The recombination rate on the q arm of Chr 6 was markedly low. Sixteen loci are informative with regard to comparative mapping, that is, they have previously been mapped in the human and/or mouse genomes.Type of Medium: Electronic ResourceURL: