Search Results - (Author, Cooperation:V. Zidek)
-
1Latest Papers from Table of Contents or Articles in PressC. McDermott-Roe ; J. Ye ; R. Ahmed ; X. M. Sun ; A. Serafin ; J. Ware ; L. Bottolo ; P. Muckett ; X. Canas ; J. Zhang ; G. C. Rowe ; R. Buchan ; H. Lu ; A. Braithwaite ; M. Mancini ; D. Hauton ; R. Marti ; E. Garcia-Arumi ; N. Hubner ; H. Jacob ; T. Serikawa ; V. Zidek ; F. Papousek ; F. Kolar ; M. Cardona ; M. Ruiz-Meana ; D. Garcia-Dorado ; J. X. Comella ; L. E. Felkin ; P. J. Barton ; Z. Arany ; M. Pravenec ; E. Petretto ; D. Sanchis ; S. A. Cook
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-10-08Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Apoptosis ; Body Weight/genetics ; Cardiomegaly/*enzymology/genetics/*pathology/physiopathology ; Cell Respiration ; Chromosomes, Mammalian/genetics ; Crosses, Genetic ; Endodeoxyribonucleases/deficiency/genetics/*metabolism ; Female ; Gene Expression Regulation ; Genes, Mitochondrial/genetics ; Hypertrophy, Left Ventricular/enzymology/genetics/pathology/physiopathology ; Lipid Metabolism ; Male ; Mitochondria/genetics/*metabolism/pathology ; Organ Size/genetics ; Quantitative Trait Loci/genetics ; RNA-Binding Proteins/metabolism ; Rats ; Rats, Inbred Strains ; Reactive Oxygen Species/metabolism ; Receptors, Estrogen/metabolism ; Transcription Factors/metabolismPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesPravenec, M. ; Zidek, V. ; Zdobinska, M. ; Kren, V. ; Krenova, D. ; Bottger, A. ; van Zutphen, L.F.M. ; Wang, J.-M. ; St. Lezin, E.
Springer
Published 1997Staff ViewISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. The genes that determine the baseline hematocrit level in humans and experimental animals are unknown. The spontaneously hypertensive rat (SHR), the most widely used animal model of human essential hypertension, exhibits an increased hematocrit when compared with the normotensive Brown Norway (BN-Lx) strain (0.54 ± 0.02 vs. 0.44 ± 0.02, p 〈 0.01). Distribution of hematocrit values among recombinant inbred (RI) strains derived from SHR and BN-Lx progenitors was continuous, which suggests a polygenic mode of inheritance. The narrow heritability of the hematocrit was estimated to be 0.32. The Eno2 marker on Chromosome (Chr) 4 showed the strongest association (p 〈 0.0001) with the observed variability of hematocrit among RI strains. The erythropoietin (Epo) gene, originally reported to be syntenic with Eno2, has been mapped to Chr 12, thus excluding it as a potential candidate gene for the increased hematocrit in the SHR. The current linkage data extend homologies between rat, mouse, and human chromosomes.Type of Medium: Electronic ResourceURL: