Search Results - (Author, Cooperation:V. V. Lobanenkov)
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1Y. Shen ; F. Yue ; D. F. McCleary ; Z. Ye ; L. Edsall ; S. Kuan ; U. Wagner ; J. Dixon ; L. Lee ; V. V. Lobanenkov ; B. Ren
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation ; Animals ; Chromatin/metabolism ; Chromatin Immunoprecipitation ; Conserved Sequence ; Enhancer Elements, Genetic/genetics ; Evolution, Molecular ; Gene Expression Regulation/*genetics ; Genome/*genetics ; Male ; Methylation ; Mice/*genetics ; Mice, Inbred C57BL ; Molecular Sequence Annotation ; Nucleotide Motifs ; Organ Specificity ; *Physical Chromosome Mapping ; Promoter Regions, Genetic/genetics ; Regulatory Sequences, Nucleic Acid/*genetics ; Sequence Analysis, DNA ; Transcription Factors/metabolismPublished by: -
2J. R. Dixon ; I. Jung ; S. Selvaraj ; Y. Shen ; J. E. Antosiewicz-Bourget ; A. Y. Lee ; Z. Ye ; A. Kim ; N. Rajagopal ; W. Xie ; Y. Diao ; J. Liang ; H. Zhao ; V. V. Lobanenkov ; J. R. Ecker ; J. A. Thomson ; B. Ren
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Allelic Imbalance/genetics ; *Cell Differentiation/genetics ; Cell Lineage/genetics ; Chromatin/*chemistry/genetics/*metabolism ; *Chromatin Assembly and Disassembly/genetics ; Embryonic Stem Cells/*cytology/*metabolism ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic/*genetics ; Epigenomics ; Gene Regulatory Networks ; Humans ; Promoter Regions, Genetic/genetics ; Reproducibility of ResultsPublished by: -
3Staff View
ISSN: 1573-8221Keywords: proteins ; matrix activity ; chromatin ; matrix ; fractionationSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1573-8221Keywords: matrix ; chromatin ; fractionationSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract By washing and subsequent centrifugation of rat liver nuclei in medium of low ionic strength the chromatin can be separated into two fractions: Chromatin eluting into the supernatant and chromatin firmly bound with the matrix. The chromatin fraction eluting into the supernatant contains about 60–70% of the original DNA and about 15% of the original protein. It has a complete set of histones and only a small quantity of nonhistone proteins. The RNA-synthesizing ability of chromatin firmly bound with the matrix is 2–3 times greater than that in the original nuclei. Data on gradient centrifugation do not allow the increase in uptake of label to be ascribed entirely to the approximately equal lengthening of chains of synthesized RNA. The increase in ability to synthesize RNA is evidently due to the larger number of molecules of RNA-polymerase per unit of DNA in the chromatin fraction firmly bound with the matrix. Comparison of the results with data in the literature indicates that the chromatin fraction bound with the matrix is enriched with transcribable genes.Type of Medium: Electronic ResourceURL: