Search Results - (Author, Cooperation:V. Gopalan)

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  1. 1
    Staff View
    Publication Date:
    2018-06-21
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Electronic structure and strongly correlated systems
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2011-07-08
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2016-04-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2013-10-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
  6. 6
    Staff View
    Publication Date:
    2018-02-15
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0099-2240
    Electronic ISSN:
    1098-5336
    Topics:
    Biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Rajendren, Gopalan V. ; Gibson, Marie J.

    Oxford, UK : Blackwell Science Ltd
    Published 1998
    Staff View
    ISSN:
    1365-2826
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    A deletion in the gene encoding gonadotropin-releasing hormone (GnRH) induces hypogonadism in mice caused by the deficiency of GnRH. Activation of the reproductive axis can be achieved in these hypogonadal (hpg) mice by third cerebro-ventricular transplantation of preoptic area (POA) containing GnRH neurons, obtained from normal fetal mice. The present study was carried out in female hpg mice with POA grafts (hpg/POA) to investigate anatomical integration of the GnRH cells required for the functional activation of the reproductive system. Ovarian development was present only in mice in which the graft tissue was located close to the median eminence (ME). The total lack of ovarian development in individuals with grafts containing GnRH cells located elsewhere in the brain suggests that the mere presence of GnRH cells does not guarantee ovarian development, but that the location of the graft may be important. Activation of the grafted GnRH cells following mating, as evidenced by the induction of Fos immunoreactivity, was observed in hpg/POA mice in which there was no ovarian development or detectable GnRH immunoreactive fiber innervation of the ME. Although ovarian development was evident in individuals with grafts located close to the ME, release of luteinizing hormone (LH) in response to mating was apparent in only some of these mice. The occurrence of mating and pregnancy only in hpg/POA mice with ovarian development and the reflex release of LH in response to mating suggests that both the efferent and afferent connections of the GnRH system are important for the full functioning of the system.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    L-655,708 is a ligand for the benzodiazepine site of the γ-aminobutyric acid type A (GABAA) receptor that exhibits a 100-fold higher affinity for α5-containing receptors compared with α1-containing receptors. Molecular biology approaches have been used to determine which residues in the α5 subunit are responsible for this selectivity. Two amino acids have been identified, α5Thr208 and α5Ile215, each of which individually confer approximately 10-fold binding selectivity for the ligand and which together account for the 100-fold higher affinity of this ligand at α5-containing receptors. L-655,708 is a partial inverse agonist at the GABAA receptor which exhibited no functional selectivity between α1- and α5-containing receptors and showed no change in efficacy at receptors containing α1 subunits where amino acids at both of the sites had been altered to their α5 counterparts (α1ΔSer205-Thr,Val212-Ile). In addition to determining the binding selectivity of L-655,708, these amino acid residues also influence the binding affinities of a number of other benzodiazepine (BZ) site ligands. They are thus important elements of the BZ site of the GABAA receptor, and further delineate a region just N-terminal to the first transmembrane domain of the receptor α subunit that contributes to this binding site.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Lai, L.B. ; Gopalan, V. ; Glew, R.H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    GOPALAN, GOPALAN V.

    Leiden : Periodicals Archive Online (PAO)
    Published 1975
    Staff View
    ISSN:
    0169-796X
    Topics:
    Political Science
    Sociology
    Notes:
    POLITICS AND THE NOVEL IN INDIA
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0009-8981
    Keywords:
    Gaucher's disease ; Glucocerebrosidase ; Heterozygote detection ; β-Glucosidase
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Balaji, Gopalan V. ; Seader, J. D.
    Springer
    Published 1995
    Staff View
    ISSN:
    1573-1340
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Computer Science
    Mathematics
    Description / Table of Contents:
    Abstract Интервальный метод Ньютона в совокупности с обобшенным мстодом деления пополам, реализованные в свободно доступном пакете программ INTBIS Кирфотта и Новоа, предназначены для решения нелинейных уравнений и их систем. В настояшей работе зтот метод применяется для решения 15 тестовых задач из различных областей химической инженерии, а также плохо масштабнрованного транцендентального уравнения. Интервальный метод, реализованный в INTBIS, способен находить все вешественные корни уравнеиия в заданной области. Комплексные корни искались путем представления каждой комплексной переменнойz=x+iy в виде двух вешественных переменныхx иy. Пля полиномиальных уравнений время счета в системе INTBIS сравнивалось с временем счета по методу продолжения параллельных траекторий Моргана, реализованному в свободно доступном пакете программ CONSOL8. В отличие от метода продолжения параллельных траекторий, который может находить все вешественные и комплексные корни без указания начальной области, INTBIS требует априорного задания начальной области. Влияние размера зтой начальной области на время счета для INTBIS было изучено на наборе полиномиальных рравнений многих переменных.
    Notes:
    Abstract The interval Newton's method in conjunction with generalized bisection, as implemented in the public domain software program INTBIS by Kearfott and Novoa, is a method of solving single and simultaneous nonlinear equations. In this paper, this method is used to solve 15 test problems from different chemical engineering application areas, and an ill-scaled transcendental equation. The interval method as implemented in INTBIS is capable of finding all the real roots of an equation within a specified domain. The complex roots were found by representing every complex variablez=x+iy by two real-valued variablesx andy. For polynomial equations, the computer time for INTBIS is compared to that of the parallel-path continuation method of Morgan as implemented in the public domain software program CONSOL8. Unlike the parallel-path continuation method, that can find all real and complex roots without specifying an initial domain. INTBIS requires the apriori specification of an initial domain. The effect of the size of the initial domain on the computer time for INTBIS was studied for a set of multi-variable polynomial equations.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Ariff, Mohamed ; Jainuddin, Md. ; Gopalan, V. ; Rao, K. Venkata

    New York : Wiley-Blackwell
    Published 1985
    Staff View
    ISSN:
    0360-6376
    Keywords:
    Physics ; Polymer and Materials Science
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    The polymerization of acrylonitrile initiated by an ascorbic acid-peroxodisulfate redox system was studied in an aqueous solution at 35°C in the presence of air. Molecular oxygen was found to have no effect on the polymerization reaction. An increase in ionic strength slightly increased the rate. The overall rate of polymerization, Rp, showed a square dependence on [monomer] and a half-order dependence on [peroxodisulfate]. A first-order dependence on [ascorbic acid] at low concentrations (〈3.0 × 10-3 mol L-1) followed by a decrease in Rp at higher concentrations of ascorbic acid (〉3.0 × 10-3 mol L-1) was also noted. Rp remained unchanged up to 40°C and showed a decline thereafter. Addition of catalytic amounts of cupric ions decreased the rate whereas ferric ions were found to increase the rate. Added sulfuric acid in the range (6.0-50.0) × 10-5 mol L-1 decreased the Rp.
    Additional Material:
    2 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses