Search Results - (Author, Cooperation:V. Andersen)

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  1. 1
    L. Jostins ; S. Ripke ; R. K. Weersma ; R. H. Duerr ; D. P. McGovern ; K. Y. Hui ; J. C. Lee ; L. P. Schumm ; Y. Sharma ; C. A. Anderson ; J. Essers ; M. Mitrovic ; K. Ning ; I. Cleynen ; E. Theatre ; S. L. Spain ; S. Raychaudhuri ; P. Goyette ; Z. Wei ; C. Abraham ; J. P. Achkar ; T. Ahmad ; L. Amininejad ; A. N. Ananthakrishnan ; V. Andersen ; J. M. Andrews ; L. Baidoo ; T. Balschun ; P. A. Bampton ; A. Bitton ; G. Boucher ; S. Brand ; C. Buning ; A. Cohain ; S. Cichon ; M. D'Amato ; D. De Jong ; K. L. Devaney ; M. Dubinsky ; C. Edwards ; D. Ellinghaus ; L. R. Ferguson ; D. Franchimont ; K. Fransen ; R. Gearry ; M. Georges ; C. Gieger ; J. Glas ; T. Haritunians ; A. Hart ; C. Hawkey ; M. Hedl ; X. Hu ; T. H. Karlsen ; L. Kupcinskas ; S. Kugathasan ; A. Latiano ; D. Laukens ; I. C. Lawrance ; C. W. Lees ; E. Louis ; G. Mahy ; J. Mansfield ; A. R. Morgan ; C. Mowat ; W. Newman ; O. Palmieri ; C. Y. Ponsioen ; U. Potocnik ; N. J. Prescott ; M. Regueiro ; J. I. Rotter ; R. K. Russell ; J. D. Sanderson ; M. Sans ; J. Satsangi ; S. Schreiber ; L. A. Simms ; J. Sventoraityte ; S. R. Targan ; K. D. Taylor ; M. Tremelling ; H. W. Verspaget ; M. De Vos ; C. Wijmenga ; D. C. Wilson ; J. Winkelmann ; R. J. Xavier ; S. Zeissig ; B. Zhang ; C. K. Zhang ; H. Zhao ; M. S. Silverberg ; V. Annese ; H. Hakonarson ; S. R. Brant ; G. Radford-Smith ; C. G. Mathew ; J. D. Rioux ; E. E. Schadt ; M. J. Daly ; A. Franke ; M. Parkes ; S. Vermeire ; J. C. Barrett ; J. H. Cho
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-11-07
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Colitis, Ulcerative/genetics/immunology/microbiology/physiopathology ; Crohn Disease/genetics/immunology/microbiology/physiopathology ; Genetic Predisposition to Disease/*genetics ; Genome, Human/genetics ; *Genome-Wide Association Study ; Haplotypes/genetics ; *Host-Pathogen Interactions/genetics/immunology ; Humans ; Inflammatory Bowel Diseases/*genetics/immunology/*microbiology/physiopathology ; Mycobacterium/*immunology/pathogenicity ; Mycobacterium Infections/genetics/microbiology ; Mycobacterium tuberculosis/immunology/pathogenicity ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Reproducibility of Results
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-04-28
    Publisher:
    BMJ Publishing
    Electronic ISSN:
    2044-6055
    Topics:
    Medicine
    Keywords:
    Clinical trials (epidemiology), Open access, Rheumatology
    Published by:
    http://group.bmj.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-02-10
    Publisher:
    BMJ Publishing
    Electronic ISSN:
    2044-6055
    Topics:
    Medicine
    Keywords:
    Open access, Medical management
    Published by:
    http://group.bmj.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    CHRISTENSEN, L. D. ; ANDERSEN, V. ; RYDER, L.

    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Published 1996
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    CD73 is a bifunctional glycosyl phosphatidylinositol anchored leucocyte differentiation antigen which has specific ecto-5′-nucleotidase (ecto-5′-NT) activity and is an accessory T-lymphocyte activation molecule. The aim of the present study was to investigate the CD73 expression on blood mononuclear cells (BMC) from a group of patients with primary immunoglobulin deficiency (IGD). This group of patients had both significantly decreased levels of ecto-5′-NT on BMC (P = 0.002) and decreased numbers of CD73 molecules per CD73+ lymphocyte (P = 0.01). Five of the 10 patients had a decreased percentage of CD73+ lymphocytes. Among B-lymphocytes the patients had normal percentages of CD73+ cells but four of the 10 patients had numbers of CD73 molecules per CD73+ B-lymphocyte below the normal range. Among CD4-lymphocytes three out of 10 patients had percentages of CD73+ below the normal range and four out of 10 patients had decreased percentages of CD73+ CD8-lymphocytes. Significant correlations were found between in vitro proliferative responses to mitogens and the number of CD73 molecules per CD73+ lymphocyte (rs = 0.60, P 〈 0.01) and per CD73+ CD8-lymphocyte (rs = 0.64, P 〈 0.02). In addition, a positive correlation was found between ability to proliferate and level of ecto-5′-NT on BMC (rs = 0.53, P 〈 0.05). Furthermore the ability of BMC to synthesize ecto-5′-NT was studied. During 2 days' culture ecto-5′-NT activity increased markedly on BMC from both patients and healthy donors. The level of activity on BMC from all patients attained levels higher than on freshly isolated BMC from healthy donors. This shows that the decreased levels of ecto-5′-NT found on freshly isolated BMC from patients with IGD is due to defective regulation of the enzyme activity in vivo
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-3083.1996.d01-281.x

    Articles: DFG German National Licenses
  5. 5
    BARINGTON, T. ; HEILMANN, C. ; ANDERSEN, V.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The human B-lymphocyte response to proiein-conjugated polysaccharide antigens has not previously been studied at the cellular level. In order to do so, we developed and evaluated haemolytic plaque-forming cell assays detecting Haemophilus influenzae type b (Hib) capsular polysaccharide-specific antibody-secreting cells (AbSC) of the isotypes IgM, IgG, and IgA. The appearance of AbSC in the blood after vaccimation of adults with diphtheria toxoid-conjugated Hib polysaccharide was investigated. AbSC were detected from post-vaccination day 5 to day 14.IgA was the predominant isotype among these cells. IgM AbSC peaked slightly earlier (median day 7) than IgG and IgA AbSC (both day 8). On post-vaccination day 8 ihe numbers of AbSC were: IgA. 1217/106 mononuclear cells (median); IgG, 211; and IgM, 30 (n= 11). Similar isotype distribution has earlier been found after vaccination with pure capsular polysaccharides from Hib and pneumococci. The predominance of IgA AbSC in response to both conjugate and pure polysaccharide vaccines is probably due to reactivation of the same clones of IgA-committed memory B cells originally primed at the mucosa by natural exposure to the polysaccharide or cross-reacting antigens.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1990.tb02799.x

    Articles: DFG German National Licenses
  6. 6
    PEDERSEN, B. K. ; KHARAZMI, A. ; THEANDER, T. G. ; ØDUM, N. ; ANDERSEN, V. ; BENDTZEN, K.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The binding of monoclonal antibodies against CD4 was specifically inhibited by treatment of human CD4+ cells with either alkaline protease (AP) or elastase (Ela), purified from Pseudomonas aeruginosa. Binding of antibodies against CD3 (pan T), CD5 (pan T), CD8 (T suppressor/cytotoxic). HLA-ABC, HLA-DR, HLA-DQ, HLA-DP/DR, and β2 microglobulin was not inhibited by AP or Ela. Heat-inactivation of the proteases at 65°C for 20 min or treatment with the metal chelator EDTA abolished the inhibitory activity of both proteases. These findings may serve to develop novel immunological methods for the isolation and study of the lymphocyte CD4 structure, which plays an important part in the immune response.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1987.tb02239.x

    Articles: DFG German National Licenses
  7. 7
    Lyngberg, K. ; Tvede, N. ; Halkjær-Kristensen, J. ; Andersen, V. ; Pedersen, B. K.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1600-0838
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Sports Science
    Notes:
    The recent findings that bicycle exercise training may reduce the number of swollen joints in patients with rheumatoid arthritis (RA) stimulated us to examine the possibility that this was mediated through exercise-induced immunomodulation. The effect of a single bout of physical exercise on blood mononuclear subsets, proliferative responses and natural killer (NK) cell activity was determined. Six patients with moderately active RA for 20 years exercised for 27 min on a bicycle, the work intensity being estimated at 68% of max V̇O2max. Blood samples were collected before and during the last minutes of exercise, as well as 2 h afterwards. During bicycle exercise the proportion of T cells (DC3+ cells) declined, mainly because of a fall in T helper cells (DC4+ cells). The proportion of NK cells (CD16+ cells) increased during work, but reverted afterwards. The monocytes (CD14+ cells) did not change; B cells (CD20+ cells) declined slightly during exercise and reverted later. No change in PHA-, PPD- and Unstimulated BMNC proliferation occurred during exercise. Two hours after exercise, PPD- and IL-2-induced proliferation increased significantly, except for the PHA-stimulated response. The NK cell activity increased only significantly during exercise when the cells were preincubated with indomethacin, and returned to normal 2 h afterwards. This shows that brief, moderate exercise by patients with RA alters the composition of blood mononuclear cell subsets and cell functions. The clinical significance of this immunomodulation remains to be elucidated.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0838.1991.tb00291.x

    Articles: DFG German National Licenses
  8. 8
    PAWLITA, M. ; ANDERSEN, V. ; LEFKOVITS, I. ; BRAUN, D. G.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1978
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The early phase of antigen-dependent triggering of rabbit blood lymphocytes (PBL) is described. Specific activation of PBL by Streptococcal vaccines requires primed lymphocytes from high responder rabbits. B-cell memory is conferred by Ig receptors of both μ and γ chains. Antigen-induced incorporation of leucine and thymidine reach peak values al day 5, with stimulation indices of 10 to 〉 100, closely followed by increases in the number of living cells. A second and less intensive phase of cell proliferation is seen on days 8–11. A large fraction of cells (between 3 and 33%) participates in proliferation. A rough calculation of the average doubling lime of cells during the exponential growth phase gives values of 8–16 h.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1978.tb00447.x

    Articles: DFG German National Licenses
  9. 9
    Fugger, L. ; Morling, N. ; Bendtzen, K. ; Ryder, L. ; Andersen, V. ; Heilman, C. ; Pedersen, F. Karup ; Friis, J. ; Halbert, P. ; Svejgaard, A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1744-313X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The restriction enzymes MspI and Bg/II identify two different two-allele restriction fragment length polymorphisms (RFLP) in the human IL-6 genes of healthy Danes. Co-dominant segregation was demonstrated for both marker-systems and the test for Hardy-Weinberg equilibrium showed no significant deviation from expectations. There is a strong correlation between the two marker systems. The two IL-6 RFLP's were studied in Danish patients with rheumatoid arthritis, pauciarticular juvenile rheumatoid arthritis, and systemic lupus erythematosus. The frequencies of the MspI and Bg/II marker phenotypes did not differ between healthy controls and the three disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1744-313X.1989.tb00495.x

    Articles: DFG German National Licenses
  10. 10
    Agger, R. ; Petersen, J. ; Dinesen, B. ; Wiik, A. ; Andersen, V.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1982
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Activation induced by pokeweed mitogen in cultures of mononuclear cells from human blood was followed sequentially by simultaneous quantitation of live cells, thymidine incorporation, cells displaying cytoplasmic IgM, IgG, IgA or IgD, cells secreting IgM, IgG or IgA and cumulated IgM secretion. Maximal cellular activity was found after 7 days of culture, with means of 16000 IgM-, 20700 IgG- and 9900 IgA-secreting cells per 106 originally cultured cells. The cumulated IgM secretion after 21 days of culture averaged 10400 ng per 106 originally cultured cells. A close correlation was found between the number of IgM-secreting cells and the cumulated IgM secretion.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1398-9995.1982.tb01894.x

    Articles: DFG German National Licenses
  11. 11
    BENDTZEN, K. ; ANDERSEN, V. ; BENDIXEN, G.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1975
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1398-9995.1975.tb01337.x

    Articles: DFG German National Licenses
  12. 12
    Andersen, V. ; Munck, B.G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0005-2736
    Keywords:
    (Rabbit ileum) ; Amino acid transport ; Brush-Border membrane ; Intestine ; β-Alanine carrier
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0005-2736(87)90145-3

    Articles: DFG German National Licenses
  13. 13
    Clausen, J. ; Andersen, V.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-8981
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-8981(63)90096-2

    Articles: DFG German National Licenses
  14. 14
    Andersen, V.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-8981
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-8981(63)90086-X

    Articles: DFG German National Licenses
  15. 15
    Hellung-Larsen, P. ; Andersen, V.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-4827
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0014-4827(69)90233-X

    Articles: DFG German National Licenses
  16. 16
    Andersen, V.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0029-554X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Energy, Environment Protection, Nuclear Power Engineering
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0029-554X(68)90570-3

    Articles: DFG German National Licenses
  17. 17
    Andersen, V.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0029-554X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Energy, Environment Protection, Nuclear Power Engineering
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0029-554X(74)90524-2

    Articles: DFG German National Licenses
  18. 18
    Hellung-Larsen, P. ; Andersen, V.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-4827
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0014-4827(68)90447-3

    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(76)90271-6

    Articles: DFG German National Licenses
  20. 20
    Andersen, V. ; Christensen, C.J. ; Borggreen, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Keywords:
    Nuclear reactions
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0375-9474(76)90685-0

    Articles: DFG German National Licenses