Search Results - (Author, Cooperation:U. Sahin)
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1Latest Papers from Table of Contents or Articles in PressT. Schumacher ; L. Bunse ; S. Pusch ; F. Sahm ; B. Wiestler ; J. Quandt ; O. Menn ; M. Osswald ; I. Oezen ; M. Ott ; M. Keil ; J. Balss ; K. Rauschenbach ; A. K. Grabowska ; I. Vogler ; J. Diekmann ; N. Trautwein ; S. B. Eichmuller ; J. Okun ; S. Stevanovic ; A. B. Riemer ; U. Sahin ; M. A. Friese ; P. Beckhove ; A. von Deimling ; W. Wick ; M. Platten
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibody Specificity ; Antigens, Neoplasm/genetics/immunology ; Cancer Vaccines/*immunology/*therapeutic use ; Female ; Glioma/enzymology/genetics/*immunology/*therapy ; Histocompatibility Antigens Class II/immunology ; Humans ; Immunity, Humoral ; Immunotherapy/methods ; Isocitrate Dehydrogenase/*genetics/*immunology ; Male ; Mice ; Mutant Proteins/genetics/*immunology ; Mutation ; T-Lymphocytes, Helper-Inducer/immunology ; Xenograft Model Antitumor AssaysPublished by: -
2Latest Papers from Table of Contents or Articles in PressS. Kreiter ; M. Vormehr ; N. van de Roemer ; M. Diken ; M. Lower ; J. Diekmann ; S. Boegel ; B. Schrors ; F. Vascotto ; J. C. Castle ; A. D. Tadmor ; S. P. Schoenberger ; C. Huber ; O. Tureci ; U. Sahin
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressS. Kreiter ; M. Vormehr ; N. van de Roemer ; M. Diken ; M. Lower ; J. Diekmann ; S. Boegel ; B. Schrors ; F. Vascotto ; J. C. Castle ; A. D. Tadmor ; S. P. Schoenberger ; C. Huber ; O. Tureci ; U. Sahin
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Algorithms ; Animals ; CD4-Positive T-Lymphocytes/immunology ; Cancer Vaccines/genetics/immunology ; Computer Simulation ; Disease Models, Animal ; Epitopes, T-Lymphocyte/*genetics/immunology ; Exome/genetics ; Female ; Histocompatibility Antigens Class II/*genetics/*immunology/metabolism ; Humans ; Immunotherapy/*methods ; Melanoma, Experimental/genetics/*immunology/*therapy ; Mice ; Mutation/*genetics ; Precision Medicine/methods ; Sequence Analysis, DNA ; Survival AnalysisPublished by: -
4Latest Papers from Table of Contents or Articles in PressSahin, U., Türeci, O.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-03-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Medicine, DiseasesPublished by: -
5Articles: DFG German National LicensesStaff View
ISSN: 1475-2743Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: GeosciencesAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract. This study investigated the effect of the same volume of leaching water applied consecutively in either equal amounts or increasing amounts or decreasing amounts on the hydraulic conductivity of a saline sodic soil in 30 cm plastic columns in the laboratory. Gypsum was mixed with the surface 2–3 cm of soil. After leaching, the hydraulic conductivity was measured in each 10 cm depth of soil. Hydraulic conductivity decreased strongly (P〈0.05) with depth and the most effective method of applying the water was in gradually increasing amounts.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1433-0415Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Trotz interdisziplinärer Ansätze und Ausreizung klassischer Therapiemodalitäten gehören Krebserkrankungen weiterhin zu den führenden Todesursachen. Neuere therapeutische Konzepte zielen darauf ab, das patienteneigene Immunsystem durch Einsatz von rekombinanten Tumorvakzinen und spezifischen immuntherapeutischen Maßnahmen in das therapeutische Gesamtkonzept mit einzubeziehen. Voraussetzung für den Erfolg einer solchen Strategie ist die Erkennung von tumorspezifischen oder tumorassoziierten Antigenen bzw. Epitopen durch das Immunsystem des Patienten, dessen Effektorfunktionen interventionell verstärkt werden sollen. Wiewohl die Existenz solcher Tumorzell-spezifischer Strukturen durch die Beobachtung humoraler und zellulärer Immunreaktionen in Tumorpatienten schon lange als gesichert galt, blieb die molekulare Struktur dieser Antigene lange Zeit unbekannt. Erst die Entwicklung von systematischen Klonierungstechniken, die etablierte zytotoxische T-Lymphozyten (CTL) bzw. zirkulierende Antikörper als Sonden verwenden, erlaubte ihre molekulare Charakterisierung. Diese Arbeit stellt die Methoden zur systematischen Identifizierung von Tumorantigenen vor, faßt identifizierte Antigenklassen zusammen und diskutiert ihre Einsatzmöglichkeiten für Diagnostik und Therapie von Malignomen.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesKaracaoglan, N. ; Velidedeoglu, H. ; Şahin, U. ; Ercan, U. ; Bozdogan, N. ; Çiçekçi, B. ; Türkgüven, Y.
Springer
Published 1994Staff ViewISSN: 1435-0130Keywords: Vaginal reconstruction ; Vaginal agenesis ; Singapore flapSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Various surgical methods for reconstruction of vaginal agenesis have been described in the past. One of these is the neurovascular pudendal thigh flap described by Wee and Joseph [20] after they studied the blood and nerve supply of upper thigh skin, medial groin, and perineum in fresh cadavers. This technique involves elevation of two flaps extending laterally to labia majora in the groin crease and suturing them to each other in the midline after bringing them through tunnels formed under the labia majora, thus, creating a new vagina. In our clinic, 24 cases of vaginal agenesis have been reconstructed with neurovascular pudendal thigh flaps in a period of 33 months. The patients were observed for eight months to three years following the operation, and only in three cases did necrosis of the distal flaps occur; hair grew in the vagina in five cases, and shrinkage was observed in only one case. This rather easy technique is the ideal reconstructive method in the vaginal agenesis. However, hair growth in the vagina must be prevented, since this is the main patient complaint.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesKaracaoglan, N. ; Velidedeoglu, H. ; Sahin, U. ; Bozdogan, N. ; Ercan, U. ; Türkgüven, Y.
Springer
Published 1995Staff ViewISSN: 1435-0130Keywords: Fasciocutaneous flap ; Lower leg defects ; Reconstruction of lower legSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Reconstruction of extensive middle third defects of the lower leg has always presented problems. Seven patients with large anterior middle third crural defects were included in this study. A combination of two different flaps were used to reconstruct the defects. In all cases, the defects were reconstructed successfully.Type of Medium: Electronic ResourceURL: