Search Results - (Author, Cooperation:U. Lang)

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  1. 1
    J. George ; J. S. Lim ; S. J. Jang ; Y. Cun ; L. Ozretic ; G. Kong ; F. Leenders ; X. Lu ; L. Fernandez-Cuesta ; G. Bosco ; C. Muller ; I. Dahmen ; N. S. Jahchan ; K. S. Park ; D. Yang ; A. N. Karnezis ; D. Vaka ; A. Torres ; M. S. Wang ; J. O. Korbel ; R. Menon ; S. M. Chun ; D. Kim ; M. Wilkerson ; N. Hayes ; D. Engelmann ; B. Putzer ; M. Bos ; S. Michels ; I. Vlasic ; D. Seidel ; B. Pinther ; P. Schaub ; C. Becker ; J. Altmuller ; J. Yokota ; T. Kohno ; R. Iwakawa ; K. Tsuta ; M. Noguchi ; T. Muley ; H. Hoffmann ; P. A. Schnabel ; I. Petersen ; Y. Chen ; A. Soltermann ; V. Tischler ; C. M. Choi ; Y. H. Kim ; P. P. Massion ; Y. Zou ; D. Jovanovic ; M. Kontic ; G. M. Wright ; P. A. Russell ; B. Solomon ; I. Koch ; M. Lindner ; L. A. Muscarella ; A. la Torre ; J. K. Field ; M. Jakopovic ; J. Knezevic ; E. Castanos-Velez ; L. Roz ; U. Pastorino ; O. T. Brustugun ; M. Lund-Iversen ; E. Thunnissen ; J. Kohler ; M. Schuler ; J. Botling ; M. Sandelin ; M. Sanchez-Cespedes ; H. B. Salvesen ; V. Achter ; U. Lang ; M. Bogus ; P. M. Schneider ; T. Zander ; S. Ansen ; M. Hallek ; J. Wolf ; M. Vingron ; Y. Yatabe ; W. D. Travis ; P. Nurnberg ; C. Reinhardt ; S. Perner ; L. Heukamp ; R. Buttner ; S. A. Haas ; E. Brambilla ; M. Peifer ; J. Sage ; R. K. Thomas
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-10-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-12-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Medicine, Diseases
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    ISSN:
    0303-7207
    Keywords:
    CHAPS ; GnRH ; GnRH receptor ; Triton ; membrane protein
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0303-7207(83)90032-1

    Articles: DFG German National Licenses
  5. 5
    Lang, U. ; Baumgartel, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0368-1874
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0368-1874(77)80153-6

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    0014-5793
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(76)80514-5

    Articles: DFG German National Licenses
  7. 7
    Lang, U. ; Schwyzer, R.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(72)80171-6

    Articles: DFG German National Licenses
  8. 8
    Lang, U. ; Wendtland, B. ; Kammermeier, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-2828
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-2828(84)80521-0

    Articles: DFG German National Licenses
  9. 9
    Walland, A. ; Streller, I. ; Lang, U.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-2828
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-2828(87)80324-3

    Articles: DFG German National Licenses
  10. 10
    Lang, U. ; Baumgartel, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0728
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-0728(77)80429-4

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0031-9422
    Keywords:
    Equisetaceae ; Equisetum telmateja ; acetylated kaempferol glycosides. ; kaempferol glycosides
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0031-9422(00)94189-X

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    0022-4731
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-4731(84)90625-3

    Articles: DFG German National Licenses
  13. 13
    Lang, U. ; Schroeder, V.
    Springer
    Published 1997
    Staff View
    ISSN:
    1420-8970
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    Abstract. We generalize Kirszbraun's extension theorem for Lipschitz maps between (subsets of) euclidean spaces to metric spaces with upper or lower curvature bounds in the sense of A.D. Alexandrov. As a by-product we develop new tools in the theory of tangent cones of these spaces and obtain new characterization results which may be of independent interest.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s000390050018

    Articles: DFG German National Licenses
  14. 14
    Lang, U. ; Pavlović, B. ; Schroeder, V.
    Springer
    Published 2000
    Staff View
    ISSN:
    1420-8970
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    Abstract. We prove that every $ \lambda $ -Lipschitz map $ f : S \to Y $ defined on a subset of an arbitrary metric space X possesses a $ c \lambda $ -Lipschitz extension $ \bar{f} : X \to Y $ for some $ c = c(Y) \ge 1 $ provided Y is a Hadamard manifold which satisfies one of the following conditions: (i) Y has pinched negative sectional curvature, (ii) Y is homogeneous, (iii) Y is two-dimensional. In case (i) the constant c depends only on the dimension of Y and the pinching constant, in case (iii) one may take $ c = 4\sqrt{2} $ . We obtain similar results for large classes of Hadamard spaces Y in the sense of Alexandrov.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/PL00001660

    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    1432-1912
    Keywords:
    K+ channel ; Estrogen ; Uterus ; Electrophysiology
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Previously it was shown that minK protein expression in uterus is regulated by estrogen. In the present study, we were interested in putative direct effects of estrogen on minK protein induced K+ currents (IminK) in Xenopus oocytes. Superfusion with 17-β-estradiol (1 μM) resulted in an inhibition of minK-induced currents, but had no appreciable effects on the delayed rectifier and inward rectifier K+ channels Kv1.1 and Kir2.1, respectively. The inhibition of IminK by 17-β-estradiol was concentration-dependent, with an IC50 of approximately 0.5 μM. In the presence of 17-β-estradiol, the conductance-voltage relationship was shifted to more depolarized potentials. IminK inhibition occurred also in the presence of the estrogen-receptor antagonist tamoxifen, suggesting that a mechanism independent of estrogen receptors is involved. The synthetic estrogen diethylstilbestrol (DES) also inhibited IminK but with a lower affinity (IC50 of 4.5 μM), while cortisol and progesterone had only weak effects on IminK. In summary, the results indicate that estrogens directly inhibit IminK.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00166894

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    1432-1912
    Keywords:
    Key words K+ channel ; Estrogen ; Uterus ; Electrophysiology
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Previously it was shown that minK protein expression in uterus is regulated by estrogen. In the present study, we were interested in putative direct effects of estrogen on minK protein induced K+ currents (IminK) in Xenopus oocytes. Superfusion with 17-β-estradiol (1 μM) resulted in an inhibition of minK-induced currents, but had no appreciable effects on the delayed rectifier and inward rectifier K+ channels Kv1.1 and Kir2.1, respectively. The inhibition of IminK by 17-β-estradiol was concentration-dependent, with an IC50 of approximately 0.5 μM. In the presence of 17-β-estradiol, the conductance-voltage relationship was shifted to more depolarized potentials. IminK inhibition occurred also in the presence of the estrogen-receptor antagonist tamoxifen, suggesting that a mechanism independent of estrogen receptors is involved. The synthetic estrogen diethylstilbestrol (DES) also inhibited IminK but with a lower affinity (IC50 of 4.5 μM), while cortisol and progesterone had only weak effects on IminK. In summary, the results indicate that estrogens directly inhibit IminK.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00166894

    Articles: DFG German National Licenses
  17. 17
    Braems, G. ; Lang, U. ; Wolff, J.
    Springer
    Published 1989
    Staff View
    ISSN:
    1432-0711
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02417199

    Articles: DFG German National Licenses
  18. 18
    Lang, U. ; Künzel, W. ; Clark, K. E.
    Springer
    Published 1999
    Staff View
    ISSN:
    1433-0393
    Keywords:
    Key words Uterine blood flow • Fetal growth • Growth restriction • Experimental IUGR ; Schlüsselwörter Uterine Durchblutung • Fetales Wachstum • Wachstumsrestriktion • Experimentelle IUWR
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Zusammenfassung Eine adäquate uteroplazentare Perfusion während der gesamten Gestationsperiode ist eine Voraussetzung plazentaren und fetalen Wachstums bei Mensch und Tier. Grundlage der adäquaten uteroplazentaren Perfusion im Gestationsverlauf ist ein stetiger, physiologischer Anstieg der uterinen Durchblutung mit zunehmendem Gestationsalter. Das kardiovaskuläre System der Mutter erfährt während der Schwangerschaft grundlegende Veränderungen, um den Feten mit nutritiven Substanzen und mit Sauerstoff zu versorgen. Ein Anpassungsvorgang an die Gravidität besteht in der Erhöhung des Herzminutenvolumens, insbesondere durch Vermehrung des Plasmavolumens. Ebenso nimmt die Herzfrequenz der Schwangeren im Verlauf der Schwangerschaft gegenüber dem nicht schwangeren Zustand zu. Der Widerstand in der uterinen Strombahn sinkt, so daß sich die Uterusperfusion gegenüber dem nicht schwangeren Zustand dramatisch erhöht und unter physiologischen Bedingungen eine ausreichende Versorgung von Plazenta und Fet gewährleistet ist. Findet die Anpassung uteroplazentarer Perfusion nicht im benötigten Umfang statt, so drohen kompensatorische Wachstumsrestriktion und fetale Mangelversorgung bis hin zur intrauterinen Asphyxie.
    Notes:
    Summary An adequate increase of uterine blood flow throughout gestation is essential for uterine, placental and fetal growth. Maternal cardiovascular adaptation has to provide the uterine perfusion that is necessary to meet the requirements of the developing and growing fetus by providing transport of nutrients and oxygen to the placenta and the fetus. Thus uterine blood flow is inextricably linked to fetal growth and survival. Reductions of uterine blood flow can occur under acute or chronic conditions or in a combination of both. Chronic reductions of uterine blood flow can be observed in pregnancy induced hyertension (PIH), diabetes mellitus in pregnancy and intrauterine growth restriction (IUGR). Chronic restrictions in uterine blood flow will elicit a placental and fetal response in the form of growth adaptation to the reduced supply of oxygen and nutrients to the conceptus. If compensatory growth restriction reaches its limits intrauterine fetal distress can ensue.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/PL00003240

    Articles: DFG German National Licenses
  19. 19
    Schauf, B. ; Lang, U. ; Künzel, W.
    Springer
    Published 1997
    Staff View
    ISSN:
    1433-0393
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s001290050165

    Articles: DFG German National Licenses
  20. 20
    Künzel, W. ; Lang, U.
    Springer
    Published 1999
    Staff View
    ISSN:
    1433-0393
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/PL00003249

    Articles: DFG German National Licenses