Search Results - (Author, Cooperation:T. Woods)
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1Raikar, S. S., Park, S. I., Leong, T., Jaye, D. L., Keller, F. G., Horan, J. T., Woods, W. G.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-02-03Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Pediatric Hematology, Myeloid Neoplasia, Lymphoid Neoplasia, Clinical Trials and ObservationsPublished by: -
2B. M. Jakosky ; J. M. Grebowsky ; J. G. Luhmann ; J. Connerney ; F. Eparvier ; R. Ergun ; J. Halekas ; D. Larson ; P. Mahaffy ; J. McFadden ; D. F. Mitchell ; N. Schneider ; R. Zurek ; S. Bougher ; D. Brain ; Y. J. Ma ; C. Mazelle ; L. Andersson ; D. Andrews ; D. Baird ; D. Baker ; J. M. Bell ; M. Benna ; M. Chaffin ; P. Chamberlin ; Y. Y. Chaufray ; J. Clarke ; G. Collinson ; M. Combi ; F. Crary ; T. Cravens ; M. Crismani ; S. Curry ; D. Curtis ; J. Deighan ; G. Delory ; R. Dewey ; G. DiBraccio ; C. Dong ; Y. Dong ; P. Dunn ; M. Elrod ; S. England ; A. Eriksson ; J. Espley ; S. Evans ; X. Fang ; M. Fillingim ; K. Fortier ; C. M. Fowler ; J. Fox ; H. Groller ; S. Guzewich ; T. Hara ; Y. Harada ; G. Holsclaw ; S. K. Jain ; R. Jolitz ; F. Leblanc ; C. O. Lee ; Y. Lee ; F. Lefevre ; R. Lillis ; R. Livi ; D. Lo ; M. Mayyasi ; W. McClintock ; T. McEnulty ; R. Modolo ; F. Montmessin ; M. Morooka ; A. Nagy ; K. Olsen ; W. Peterson ; A. Rahmati ; S. Ruhunusiri ; C. T. Russell ; S. Sakai ; J. A. Sauvaud ; K. Seki ; M. Steckiewicz ; M. Stevens ; A. I. Stewart ; A. Stiepen ; S. Stone ; V. Tenishev ; E. Thiemann ; R. Tolson ; D. Toublanc ; M. Vogt ; T. Weber ; P. Withers ; T. Woods ; R. Yelle
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-11-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3S. Bougher ; B. Jakosky ; J. Halekas ; J. Grebowsky ; J. Luhmann ; P. Mahaffy ; J. Connerney ; F. Eparvier ; R. Ergun ; D. Larson ; J. McFadden ; D. Mitchell ; N. Schneider ; R. Zurek ; C. Mazelle ; L. Andersson ; D. Andrews ; D. Baird ; D. N. Baker ; J. M. Bell ; M. Benna ; D. Brain ; M. Chaffin ; P. Chamberlin ; J. Y. Chaufray ; J. Clarke ; G. Collinson ; M. Combi ; F. Crary ; T. Cravens ; M. Crismani ; S. Curry ; D. Curtis ; J. Deighan ; G. Delory ; R. Dewey ; G. DiBraccio ; C. Dong ; Y. Dong ; P. Dunn ; M. Elrod ; S. England ; A. Eriksson ; J. Espley ; S. Evans ; X. Fang ; M. Fillingim ; K. Fortier ; C. M. Fowler ; J. Fox ; H. Groller ; S. Guzewich ; T. Hara ; Y. Harada ; G. Holsclaw ; S. K. Jain ; R. Jolitz ; F. Leblanc ; C. O. Lee ; Y. Lee ; F. Lefevre ; R. Lillis ; R. Livi ; D. Lo ; Y. Ma ; M. Mayyasi ; W. McClintock ; T. McEnulty ; R. Modolo ; F. Montmessin ; M. Morooka ; A. Nagy ; K. Olsen ; W. Peterson ; A. Rahmati ; S. Ruhunusiri ; C. T. Russell ; S. Sakai ; J. A. Sauvaud ; K. Seki ; M. Steckiewicz ; M. Stevens ; A. I. Stewart ; A. Stiepen ; S. Stone ; V. Tenishev ; E. Thiemann ; R. Tolson ; D. Toublanc ; M. Vogt ; T. Weber ; P. Withers ; T. Woods ; R. Yelle
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-11-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
4Winkler, C. W., Woods, T. A., Robertson, S. J., McNally, K. L., Carmody, A. B., Best, S. M., Peterson, K. E.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-01-09Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
5Stark, J. C., Huang, A., Nguyen, P. Q., Dubner, R. S., Hsu, K. J., Ferrante, T. C., Anderson, M., Kanapskyte, A., Mucha, Q., Packett, J. S., Patel, P., Patel, R., Qaq, D., Zondor, T., Burke, J., Martinez, T., Miller-Berry, A., Puppala, A., Reichert, K., Schmid, M., Brand, L., Hill, L. R., Chellaswamy, J. F., Faheem, N., Fetherling, S., Gong, E., Gonzalzles, E. M., Granito, T., Koritsaris, J., Nguyen, B., Ottman, S., Palffy, C., Patel, A., Skweres, S., Slaton, A., Woods, T., Donghia, N., Pardee, K., Collins, J. J., Jewett, M. C.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-08-02Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
6A.K. Rumaiz, A.J. Kuczewski, J. Mead, E. Vernon, D. Pinelli, E. Dooryhee, S. Ghose, T. Caswell, D.P. Siddons, A. Miceli, J. Baldwin, J. Almer, J. Okasinski, O. Quaranta, R. Woods, T. Krings and S. Stock
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-04-28Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
7Jennings, I. ; Kitchen, S. ; Woods, T. A. L. ; Preston, F. E.
Oxford UK : Blackwell Science Ltd
Published 1998Staff ViewISSN: 1365-2516Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A World Federation of Hemophilia External Quality Assessment Scheme has been established to promote high standards of laboratory performance in haemophilia centres worldwide. Results from 21 International Haemophilia Training Centres (IHTCs) provide target values for the prothrombin time (PT), activated partial thromboplastin time (APTT), factor VIII:C, IX:C and von Willebrand factor (VWF) assays, against which the performance of Haemophilia Centres in developing countries (HCs) can be assessed.Eight surveys were distributed over a 3-year period between 1994 and 1997. A higher proportion of HCs failed to identify an abnormal PT or APTT in samples from donors with mild deficiencies of the extrinsic and intrinsic systems, respectively. For factor VIII:C and IX:C assays, agreement between HC results was consistently poorer than between IHTCs. However, improvement in between-centre agreement could be seen for two samples distributed on more than one occasion. A minority of HCs perform assays for VWF, and a questionnaire revealed equipment and reagent costs as limiting the range of assays which could be carried out in several centres. However, agreement was in some cases better between those HCs that did perform VWF assays than between IHTCs. The problems of screening test sensitivity and between-centre agreement for factor assays need to be addressed, together with the limitations which prevent HCs from performing a full range of tests in the diagnosis and treatment of bleeding disorders.Type of Medium: Electronic ResourceURL: -
8JENNINGS, I. ; KITCHEN, S. ; WOODS, T. A. L. ; PRESTON, F. E.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1365-2516Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. A World Federation of Hemophilia External Quality Assessment Scheme has been established to promote high standards of laboratory performance in haemophilia centres worldwide. Twenty-two International Haemophilia Training Centres (IHTCs) participated in a pilot study designed to assess between-laboratory agreement and to establish target values for the prothrombin time, activated partial thromboplastin time, factor VIII:C, IX:C and von Willebrand factor assays. Although variations in results and clinical interpretations were observed between the centres, median results and assay precision were comparable to that seen in the United Kingdom National External Quality Assessment Scheme. IHTC-generated median results were therefore considered appropriate target values against which to compare the performance of haemophilia centres in developing countries.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] I BEG to call the attention of geologists to the following facts:—On the north-east coast of Australia, at the end of Trinity Bay, about lat. 17° S., there are steep ranges of granite abutting on the sea-margin. Every rainy season (December, January, and February) immense quantities of the ...Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0042-207XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsType of Medium: Electronic ResourceURL: -
11Feldman, P. D. ; A'Hearn, M. F. ; Festou, M. C. ; McFadden, L. A. ; Weaver, H. A. ; Woods, T. N.
[s.l.] : Nature Publishing Group
Published 1986Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Data were obtained during a combined 16 h US1-US2 IUE shift on 18 March 1986 beginning at 11:00 UT. Observations consisted of a large number of relatively short exposures taken at various offset distances from the nucleus with the long-wavelength (LWP) spectrograph to map the spatial distribution ...Type of Medium: Electronic ResourceURL: -
12Woods, T. N. ; Feldman, P. D. ; Dymond, K. F. ; Sahnow, D. J.
[s.l.] : Nature Publishing Group
Published 1986Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Atomic carbon is a common feature in the ultraviolet spectrum of many comets, yet its origin remains unclear.. In comet West (1976 VI), the observed C I emission was consistent with a model of carbon as a daugher of CO which is vaporized from the nucleus as a parent molecule3. However, for comet ...Type of Medium: Electronic ResourceURL: -
13Engineering protein-based machines to emulate key steps of metabolism (biological energy conversion)Urry, D. W. ; Peng, S. Q. ; Hayes, L. C. ; McPherson, D. ; Xu, J. ; Woods, T. C. ; Gowda, D. C. ; Pattanaik, A.
New York, NY [u.a.] : Wiley-Blackwell
Published 1998Staff ViewISSN: 0006-3592Keywords: protein-based polymers ; inverse temperature transitions ; hydrophobic-induced pKa shifts ; waters of hydrophobic hydration ; five axioms for protein engineering; microwave dielectric relaxation ; a universal mechanism for biological energy conversion ; Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Metabolism is the conversion of available energy sources to those energy forms required for sustaining and propagating living organisms; this is simply biological energy conversion. Proteins are the machines of metabolism; they are the engines of motility and the other machines that interconvert energy forms not involving motion. Accordingly, metabolic engineering becomes the use of natural protein-based machines for the good of society. In addition, metabolic engineering can utilize the principles, whereby proteins function, to design new protein-based machines to fulfill roles for society that proteins have never been called upon throughout evolution to fulfill.This article presents arguments for a universal mechanism whereby proteins perform their diverse energy conversions; it begins with background information, and then asserts a set of five axioms for protein folding, assembly, and function and for protein engineering. The key process is the hydrophobic folding and assembly transition exhibited by properly balanced amphiphilic protein sequences. The fundamental molecular process is the competition for hydration between hydrophobic and polar, e.g., charged, residues. This competition determines Tt, the onset temperature for the hydrophobic folding and assembly transition, Nhh, the numbers of waters of hydrophobic hydration, and the pKa of ionizable functions.Reported acid-base titrations and pH dependence of microwave dielectric relaxation data simultaneously demonstrate the interdependence of Tt, Nhh and the pKa using a series of microbially prepared protein-based poly(30mers) with one glutamic acid residue per 30mer and with an increasing number of more hydrophobic phenylalanine residues replacing valine residues. Also, reduction of nicotinamides and flavins is shown to lower Tt, i.e., to increase hydrophobicity.Furthermore, the argument is presented, and related to an extended Henderson-Hasselbalch equation, wherein reduction of nicotinamides represents an increase in hydrophobicity and resulting hydrophobic-induced pKa shifts become the basis for understanding a primary energy conversion (proton transport) process of mitochondria. © 1998 John Wiley & Sons, Inc. Biotechnol Bioeng 58:175-190, 1998.Additional Material: 11 Ill.Type of Medium: Electronic Resource -
14Staff View
ISSN: 1741-2765Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Nuclear fuel can be fabricated using powder-metallurgy processes by compacting uranium-oxide powder with aluminum powder to form a cermet and then extruding the cermet to form fuel tubes. This method of production allows greater control of uranium-oxide particle size and distribution in the tube, making the production of fuel with greater concentrations of uranium oxide possible, and thus decreasing the volume of radioactive waste remaining after the fuel is spent. As the concentration of uranium oxide increases, however, there is an increase in failures during extrusion. To address this problem, an experimental procedure was developed to examine the response of powder aluminum, a material with a structure similar to that of the cermet fuel, to biaxial loadings such as those experienced during extrusion. Biaxial loadings can be varied from pure shear to simple tension or compression, or to combinations of these loadings in a numerically controlled ‘tension-torsion’ testing machine. Data obtained using this system were used to develop a model for the post-yield behavior in extruded powder aluminum which includes information derived both from the macroscopic stress-strain behavior of 1100 aluminum and extruded powder aluminum and from the observed microscopic structure of the extruded powder aluminum. This paper describes the development of the experimental system and shows the different biaxial mechanical behavior of the two materials. Test fixtures were developed and software was written to control constant strain-rate tension, compression, torsion, combined tension-torsion, and combined compression-torsion tests performed using a computer-controlled MTS biaxial testing machine. Extruded powder aluminum and 1100 aluminum specimens were tested at 427°C, the powder-aluminum extrusion temperature, under those loading conditions. Each specimen was subjected to only one loading cycle. Data were recorded during loading only. Tested specimens were also sectioned and examined microscopically.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1741-2765Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract This paper proposes a model and a mechanism for explaining the mechanical behavior of extruded powder aluminum at elevated temperature. This behavior is significantly different from that of ingot-cast and drawn aluminum which is subjected to the same tests. Powder aluminum exhibits a strain-softening effect which is evident in a decrease of stress with increasing strain in uniaxial test specimens when the experiment proceeds into the postyield region. Similar behavior is observed in the shear response during biaxial tension-torsion loading. For these tests, the shear stress is additionally reduced with increased axial extension. A model and mechanism are proposed, based on the relative motion of the extruded aluminum particles, to explain this effect. Equations are derived which relate the axial and shear stresses and strains. These equations are fitted to data obtained in a matrix of experiments, which include combined loadings from uniaxial tension to simple shear. Results are presented graphically and are in good agreement with the proposed models.Type of Medium: Electronic ResourceURL: