Search Results - (Author, Cooperation:T. Visakorpi)

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  1. 1
    J. M. Tubio ; Y. Li ; Y. S. Ju ; I. Martincorena ; S. L. Cooke ; M. Tojo ; G. Gundem ; C. P. Pipinikas ; J. Zamora ; K. Raine ; A. Menzies ; P. Roman-Garcia ; A. Fullam ; M. Gerstung ; A. Shlien ; P. S. Tarpey ; E. Papaemmanuil ; S. Knappskog ; P. Van Loo ; M. Ramakrishna ; H. R. Davies ; J. Marshall ; D. C. Wedge ; J. W. Teague ; A. P. Butler ; S. Nik-Zainal ; L. Alexandrov ; S. Behjati ; L. R. Yates ; N. Bolli ; L. Mudie ; C. Hardy ; S. Martin ; S. McLaren ; S. O'Meara ; E. Anderson ; M. Maddison ; S. Gamble ; C. Foster ; A. Y. Warren ; H. Whitaker ; D. Brewer ; R. Eeles ; C. Cooper ; D. Neal ; A. G. Lynch ; T. Visakorpi ; W. B. Isaacs ; L. van't Veer ; C. Caldas ; C. Desmedt ; C. Sotiriou ; S. Aparicio ; J. A. Foekens ; J. E. Eyfjord ; S. R. Lakhani ; G. Thomas ; O. Myklebost ; P. N. Span ; A. L. Borresen-Dale ; A. L. Richardson ; M. Van de Vijver ; A. Vincent-Salomon ; G. G. Van den Eynden ; A. M. Flanagan ; P. A. Futreal ; S. M. Janes ; G. S. Bova ; M. R. Stratton ; U. McDermott ; P. J. Campbell
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-08-02
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Carcinogenesis/genetics ; Chromatin/chemistry ; *DNA Transposable Elements ; Exons ; Genome, Human ; Humans ; *Long Interspersed Nucleotide Elements ; Mutagenesis, Insertional ; Neoplasms/*genetics ; *Transduction, Genetic ; Translocation, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-04-02
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Androgens/deficiency ; *Cell Lineage/genetics ; Clone Cells/metabolism/pathology ; DNA Mutational Analysis ; Disease Progression ; Epigenesis, Genetic ; Genes, Tumor Suppressor ; Humans ; Male ; Neoplasm Metastasis/genetics/*pathology ; Prostatic Neoplasms/genetics/metabolism/*pathology ; Receptors, Androgen/metabolism ; Signal Transduction/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
  4. 4
    Staff View
    ISSN:
    0165-4608
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
  6. 6
    Staff View
    ISSN:
    0942-0940
    Keywords:
    Haemangiopericytoma ; intracranial ; outcome ; proliferation indices ; p53
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Cell proliferation indices of 31 primary intracranial haemangiopericytomas (HPC) and their recurrences and metastases were correlated with the long-term recurrence, metastasis and survival rates. Paraffin-embedded specimens were used for K-67, PCNA and p53 immunostainings and for estimation of S-phase fraction (S-PF) in flow cytometry. The median Ki-67 and PCNA indices and S-PFs were 10.4, 3.2, and 4.0 for primary HPCs and 14.1, 14.1, and 5.5 for recurrences, respectively. High indices were associated with higher recurrence, metastasis and death rates, but not at the p ≤ 0.5 level. Consequently, these indices do not seem useful in planning of treatment and follow-up of meningeal HPCs. Meningeal HPCs, in contrast to meningiomas, recur almost always despite seemingly complete removal and often metastasize elsewhere in the body. This difference between two sharply demarcated tumours must reflect particularly adhesive and infiltrative properties of HPC cells and not just higher proliferation potential.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses