Search Results - (Author, Cooperation:T. Vasankari)

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  1. 1
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Chambers ; J. S. Kooner ; D. P. Strachan ; H. Campbell ; J. N. Hirschhorn ; M. Perola ; O. Polasek ; J. F. Wilson
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-02
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Biological Evolution ; Blood Pressure/genetics ; Body Height/*genetics ; Cholesterol, LDL/genetics ; *Cognition ; Cohort Studies ; Educational Status ; Female ; Forced Expiratory Volume/genetics ; Genome, Human/genetics ; *Homozygote ; Humans ; Lung Volume Measurements ; Male ; Phenotype
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Kujala, U. M. ; Ahotupa, M. ; Vasankari, T. ; Kaprio, J. ; Tikkanen, M.J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1600-0838
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Sports Science
    Notes:
    The ‘oxidation hypothesis’ states that oxidative modification of low-density lipoprotein (LDL) is important in the pathogenesis of the atherosclerotic lesion. Physical exercise has been reported to reduce clinical manifestations of atherosclerosis. We compared the effects of aerobic physical exercise history on oxidation characteristics of plasma LDL at rest in non-smoking male veteran endurance athletes (n= 15) and control subjects (n= 16). As an indicator of LDL oxidation we used a method which provides an estimate of LDL diene conjugation in vivo. The athletes had lower plasma LDL cholesterol diene conjugation (P= 0.003). They also had lower cholesterol, lower LDL and higher high-density lipoprotein (HDL) cholesterol. Intensive physical exercise energy expenditure correlated inversely with LDL diene conjugation (r=−0.41, P= 0.021). We conclude that participation in intensive physical exercise training is associated with reduced plasma LDL fraction oxidation as reflected by LDL diene conjugation. This finding may have relevance for studies aiming to explain the variation in occurrence of ischemic heart disease.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0838.1996.tb00475.x

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    1439-6327
    Keywords:
    Altitude ; Cortisol ; Exercise ; Growth hormone ; Testosterone
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The effect of similar prolonged exercise on hormonal changes was studied at sea level and at moderate altitude. Four cross-country skiers participated in a 30-km race and five biathlonists in a 20-km race at sea level in Finland and during altitude training and racing at 1650 m in Les Saisies, France. Venous blood samples were taken at both altitudes before the race between 0800 and 0900 hours and 25–35 min after the race. Resting blood samples were also taken before and after the altitude training and the period of racing. Serum testosterone concentration was higher before the race at altitude than at sea level (19%, P〈0.02), and 30 min after the race growth hormone (GH) concentration was higher at sea level than at moderate altitude (P〈0.002). There were not significant differences in serum luteinising hormone between the altitudes. Serum cortisol concentration was higher after the altitude training and the period of racing than before (P〈0.02) but no difference was observed in testosterone. We concluded, that since the profiles of the anabolic-catabolic hormone concentrations measured are indicators of the performance level of athletes, our data indicated that to follow them during altitude training could be beneficial in optimizing training programme for individual athletes. We also concluded, that the lower GH concentration after racing at moderate altitude may have been a consequence of decreased racing speed and/or increased physical performance.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00235097

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1439-6327
    Keywords:
    Key words Altitude  ;  Antioxidant capacity  ;   Diene conjugation  ;  Exercise  ;  Oxidative stress
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract We investigated the effect of training and racing at moderate altitude (MA) on oxidative stress by assessment of serum diene conjugation (DC) and serum antioxidant potential (TRAP). Nine male top level skiers were studied during a national race (20–30 km) at sea level (SL). Thereafter, the athletes trained for 2 weeks at MA, after which they participated in a 20–30 km race at MA. Venous blood samples were taken before and after the race. The DC, indicating early events of lipid peroxi dation, did not change during the race at SL (16 850 vs 15 900 ΔAbsorbance · l−1) or at MA (19 870 vs. 20 630 ΔAbs · l−1). At MA serum DC was higher than at SL both before (25%) and after (30%) the race, the postrace difference being statistically significant (P 〈 0.05). The TRAP increased during the race at MA (from 1387 to 1943 μmol · 1−1, P  =  0.016), but not at SL (1713 vs 1582 μmol · l−1). These observations would suggest that the level of oxidative stress might be greater during living, training and racing at MA (higher DC levels). Increased TRAP during the race at MA may indicate that the physiological adaptation to extreme acute oxidative stress was altered. The physiological significance of this observation remains to be investigated.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004210050178

    Articles: DFG German National Licenses
  5. 5
    Staff View
    Type of Medium:
    Online
    Publication Date:
    2017
    Keywords:
    Fragebogen ; Konformität ; Wohlbefinden ; Selbstbeobachtung ; Muskelkraft ; Gesundheitserziehung ; Gesundheitsförderung ; Gesundheitsfürsorge ; Gesundheitspolitik ; Gesundheitswesen ; Gleichgewichtsübung ; Gesundheitssport ; Sportmedizin ; Sportsoziologie ; Erwachsener ; Finnland
    In:
    Scandinavian journal of medicine & science in sports, Bd. 27 (2017) H. 12, S. 1842-1853, 0905-7188
    1600-0838
    Language:
    English

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