Search Results - (Author, Cooperation:T. Tong)
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1J. Huang ; B. H. Kang ; M. Pancera ; J. H. Lee ; T. Tong ; Y. Feng ; H. Imamichi ; I. S. Georgiev ; G. Y. Chuang ; A. Druz ; N. A. Doria-Rose ; L. Laub ; K. Sliepen ; M. J. van Gils ; A. T. de la Pena ; R. Derking ; P. J. Klasse ; S. A. Migueles ; R. T. Bailer ; M. Alam ; P. Pugach ; B. F. Haynes ; R. T. Wyatt ; R. W. Sanders ; J. M. Binley ; A. B. Ward ; J. R. Mascola ; P. D. Kwong ; M. Connors
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-09-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: AIDS Vaccines/chemistry/immunology ; Antibodies, Monoclonal/chemistry/genetics/immunology/pharmacology ; Antibodies, Neutralizing/chemistry/genetics/*immunology/pharmacology ; *Antibody Affinity ; Antibody Specificity ; Antigens, CD4/metabolism ; Cell Line ; Cell Membrane/virology ; Conserved Sequence ; Epitope Mapping ; Epitopes/chemistry/immunology ; HIV Antibodies/chemistry/genetics/*immunology/pharmacology ; HIV Envelope Protein gp120/*chemistry/*immunology ; HIV Envelope Protein gp41/*chemistry/*immunology ; HIV-1/drug effects/immunology ; Humans ; Immunoglobulin Fab Fragments/chemistry/genetics/immunology/ultrastructure ; Inhibitory Concentration 50 ; Leukocytes, Mononuclear ; Models, Molecular ; Molecular Sequence Data ; Receptors, CCR5/metabolism ; Virus Internalization/drug effectsPublished by: -
2Y. Song ; L. Li ; Y. Ou ; Z. Gao ; E. Li ; X. Li ; W. Zhang ; J. Wang ; L. Xu ; Y. Zhou ; X. Ma ; L. Liu ; Z. Zhao ; X. Huang ; J. Fan ; L. Dong ; G. Chen ; L. Ma ; J. Yang ; L. Chen ; M. He ; M. Li ; X. Zhuang ; K. Huang ; K. Qiu ; G. Yin ; G. Guo ; Q. Feng ; P. Chen ; Z. Wu ; J. Wu ; J. Zhao ; L. Luo ; M. Fu ; B. Xu ; B. Chen ; Y. Li ; T. Tong ; M. Wang ; Z. Liu ; D. Lin ; X. Zhang ; H. Yang ; Q. Zhan
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-03-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alcohol Drinking/adverse effects ; Biomarkers, Tumor/genetics ; Carcinoma, Squamous Cell/*genetics/pathology ; Cell Cycle/genetics ; Chromosomes, Human, Pair 11/genetics ; Comparative Genomic Hybridization ; DNA Copy Number Variations/genetics ; Esophageal Neoplasms/*genetics/pathology ; Exome/genetics ; Female ; Genome, Human/*genetics ; Genomics ; Histones/metabolism ; Humans ; Male ; MicroRNAs/genetics ; Mutation/*genetics ; Oncogenes/genetics ; Phenotype ; Receptors, Notch/genetics ; Risk Factors ; Wnt Signaling Pathway/geneticsPublished by: -
3P. Ranitovic, F. P. Sturm, X. M. Tong, T. W. Wright, D. Ray, I. Zalyubovskya, N. Shivaram, A. Belkacem, D. S. Slaughter, and Th. Weber
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-07-17Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Atomic and molecular processes in external fields, including interactions with strong fields and short pulsesPublished by: -
4Branch, D. R., Hellberg, A., Bruggeman, C. W., Storry, J. R., Sakac, D., Blacquiere, M., Tong, T. N., Burke-Murphy, E., Binnington, B., Parmar, N., Riden, L. S., Willie, K., Armali, C., Aziz, J., Lieberman, L., Laroche, V., Callum, J., Lin, Y., Shehata, N., Pavenski, K., Lau, W., Hannach, B., Kuijpers, T. W., Olsson, M. L., Cserti-Gazdewich, C., Pendergrast, J.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-02-16Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Transfusion MedicinePublished by: -
5Hung, W. K. ; Wong, W. M. ; Wong, G. S. W. ; Yip, A. W. C. ; Szeto, M. L. ; Lai, K. C. ; Hu, W. H. C. ; Chan, C. K. ; Xia, H. H. X. ; Yuen, M. F. ; Fung, F. M. Y. ; Tong, T. S. M. ; Ho, V. Y. K. ; Lam, S. K. ; Wong, B. C. Y.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : We have previously shown that ranitidine bismuth citrate-based, clarithromycin-containing triple therapy achieves a higher eradication rate than proton pump inhibitor-based regimens in areas with a high prevalence of metronidazole resistance.Aim : To evaluate whether this higher efficacy of ranitidine bismuth citrate over proton pump inhibitor can be extended to non-clarithromycin-containing regimens.Methods : Helicobacter pylori-positive dyspeptic patients were randomized to receive either ranitidine bismuth citrate, 400 mg, amoxicillin, 1000 mg, and metronidazole, 400 mg, or omeprazole, 20 mg, amoxicillin, 1000 mg, and metronidazole, 400 mg, each given twice daily for 1 week. H. pylori eradication was confirmed by 13C-urea breath test 5 weeks later. The side-effects of the treatments were documented.Results : Two hundred and twenty-nine patients were eligible for analysis. By intention-to-treat and per protocol analysis, the eradication rates were 77% and 79%, respectively, in the ranitidine bismuth citrate–amoxicillin–metronidazole group and 77% and 82%, respectively, in the omeprazole–amoxicillin–metronidazole group (P = 0.58 and P = 0.65). However, patients in the omeprazole–amoxicillin–metronidazole group reported a significantly higher incidence of minor side-effects when compared to those in the ranitidine bismuth citrate–amoxicillin–metronidazole group (P = 0.001).Conclusions : Ranitidine bismuth citrate–amoxicillin–metronidazole was equally as effective as omeprazole–amoxicillin–metronidazole triple therapy, and may be considered as an alternative non-clarithromycin-based regimen in the Chinese population.Type of Medium: Electronic ResourceURL: -
6Wong, B. C.-Y. ; Wong, W. M. ; Cheung, K. L. ; Tong, T. S. M. ; Rozen, P. ; Young, G. P. ; Chu, K. W. ; Ho, J. ; Law, W. L. ; Tung, H. M. ; Lai, K. C. ; Hu, W. H. C. ; Chan, C. K. ; Lam, S. K.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : Colorectal cancer screening by guaiac faecal occult blood test has been shown to reduce the incidence and mortality of colorectal cancer in Western populations. The optimal faecal occult blood test, whether guaiac or immunochemical, for colorectal cancer screening in the Chinese population remains to be defined.Aim : To compare the performance characteristics of a sensitive guaiac-based faecal occult blood test (Hemoccult SENSA) and an immunochemical faecal occult blood test (FlexSure OBT) in a Chinese population referred for colonoscopy.Methods : One hundred and thirty-five consecutive patients who were referred for colonoscopy and who met the study inclusion criteria took samples for the two faecal occult blood tests simultaneously from three successive stool specimens, with no dietary restrictions. All tests were developed and interpreted by a single experienced technician who was blind to the clinical diagnosis. The sensitivity, specificity and positive predictive value for the detection of colorectal adenomas and cancers were estimated for the two tests.Results : The sensitivity, specificity and positive predictive value for the detection of significant colorectal neoplasia (adenomas ≥ 1.0 cm and cancers) were 91%, 70% and 18% for Hemoccult SENSA and 82%, 94% and 47% for FlexSure OBT. The specificity and positive predictive value were significantly higher for FlexSure OBT than for Hemoccult SENSA (P 〈 0.001 and P = 0.016, respectively). Combining the positive results from both faecal occult blood tests did not improve the accuracy.Conclusion : The positive predictive value of the immunochemical faecal occult blood test for the detection of significant colorectal neoplasia was 29% better than that of the sensitive guaiac-based test. This may relate to the Chinese diet and requires further study. The poor specificity of the sensitive guaiac-based test, without dietary restriction, makes it less useful for colorectal cancer screening in a Chinese population.Type of Medium: Electronic ResourceURL: -
7Wong, B. C. Y. ; Wong, W. M. ; Yee, Y. K. ; Hung, W. K. ; Yip, A. W. C. ; Szeto, M. L. ; Li, K. F. ; Lau, P. ; Fung, F. M. Y. ; Tong, T. S. M. ; Lai, K. C. ; Hu, W. H. C. ; Yuen, M. F. ; Hui, C. K. ; Lam, S. K.
Oxford UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Rabeprazole is a new proton pump inhibitor with more potent acid suppressive and anti-Helicobacter effects.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To compare two different regimens of rabeprazole-based triple therapy vs. 7-day omeprazole-based triple therapy for the eradication of Helicobacter pylori infection.〈section xml:id="abs1-3"〉〈title type="main"〉Method:Patients with proven H. pylori infection were randomized to receive: (i) 7-day rabeprazole, 10 mg, amoxicillin, 1000 mg, and clarithromycin, 500 mg, all twice daily; (ii) 3-day rabeprazole, 20 mg, amoxicillin, 1000 mg, and clarithromycin, 500 mg, all twice daily; or (iii) 7-day omeprazole, 20 mg, amoxicillin, 1000 mg, and clarithromycin, 500 mg, all twice daily. Endoscopy (CLO test, histology) was performed before randomization and 6 weeks after drug treatment.〈section xml:id="abs1-4"〉〈title type="main"〉Results:One hundred and seventy-three patients were randomized. H. pylori eradication rates (intention-to-treat, n=173/per protocol, n=167) were 88%/91% for 7-day rabeprazole-based therapy, 72%/72% for 3-day rabeprazole-based therapy and 82%/89% for 7-day omeprazole-based therapy, respectively. The per protocol eradication rate was significantly better in the 7-day rabeprazole-based therapy and 7-day omeprazole-based therapy groups when compared to the 3-day rabeprazole-based therapy group (P=0.01 and P=0.04, respectively). Compliance was excellent and all three regimens were well tolerated.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:The efficacy of seven-day rabeprazole-based triple therapy is similar to 7-day omeprazole-based triple therapy for the eradication of H. pylori infection.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0047-6374Keywords: 2BS fibroblasts ; Cell aging ; Epidermal growth factor ; HER-2 ; SenescenceSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
10Tong, T. K. ; Hartenberg, M. A. ; Mickell, J. J. ; Mulroy, J. J. ; Friedman, B. I.
Springer
Published 1985Staff ViewISSN: 1432-1998Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Three children requiring selective endobronchial intubation were treated with a technique utilizing an angiographic catheter as a guide for the endotracheal tube. The procedure was successful in all three children and there were no long-term complications. Performed properly the technique is rapid, safe and avoids uncontrolled attempts at endobronchial intubation or the need for a flexible fiberoptic bronchoscope.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0146-3535Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0021-9118Topics: Political ScienceEconomicsNotes: BOOK REVIEWSURL: -
13Friedman, B. I. ; Hartenberg, M. A. ; Mulroy, J. J. ; Tong, T. K. ; Mickell, J. J.
Springer
Published 1986Staff ViewISSN: 1432-1998Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract A case of Gastrografin aspiration in a 3 3/4-year-old child admitted for multiple trauma is described.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1432-1076Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
15Scholte, H. R. ; Trijbels, J. M. F. ; Applegarth, D. A. ; Tong, T. ; Clarke, L. A.
Springer
Published 1995Staff ViewISSN: 1432-1076Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: