Search Results - (Author, Cooperation:T. Sanger)
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1Latest Papers from Table of Contents or Articles in PressJ. Alfoldi ; F. Di Palma ; M. Grabherr ; C. Williams ; L. Kong ; E. Mauceli ; P. Russell ; C. B. Lowe ; R. E. Glor ; J. D. Jaffe ; D. A. Ray ; S. Boissinot ; A. M. Shedlock ; C. Botka ; T. A. Castoe ; J. K. Colbourne ; M. K. Fujita ; R. G. Moreno ; B. F. ten Hallers ; D. Haussler ; A. Heger ; D. Heiman ; D. E. Janes ; J. Johnson ; P. J. de Jong ; M. Y. Koriabine ; M. Lara ; P. A. Novick ; C. L. Organ ; S. E. Peach ; S. Poe ; D. D. Pollock ; K. de Queiroz ; T. Sanger ; S. Searle ; J. D. Smith ; Z. Smith ; R. Swofford ; J. Turner-Maier ; J. Wade ; S. Young ; A. Zadissa ; S. V. Edwards ; T. C. Glenn ; C. J. Schneider ; J. B. Losos ; E. S. Lander ; M. Breen ; C. P. Ponting ; K. Lindblad-Toh
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-09-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Birds/*genetics ; Chickens/genetics ; *Evolution, Molecular ; GC Rich Sequence/genetics ; Genome/*genetics ; Genomics ; Humans ; Lizards/*genetics ; Mammals/*genetics ; Molecular Sequence Data ; Phylogeny ; Synteny/genetics ; X Chromosome/geneticsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1432-0770Source: Springer Online Journal Archives 1860-2000Topics: BiologyComputer SciencePhysicsNotes: Abstract A solution to the correspondence problem for stereopsis is proposed using the differences in the complex phase of local spatial frequency components. One-dimensional spatial Gabor filters (Gabor 1946; Marcelja 1980), at different positions and spatial frequencies are convolved with each member of a stereo pair. The difference between the complex phase at corresponding points in the two images is used to find the stereo disparity. Disparity values are combined across spatial frequencies for each image location. Three-dimensional depth maps have been computed from real images under standard lighting conditions, as well as from random-dot stereograms (Julesz 1971). The algorithm can discriminate disparities significantly smaller than the width of a pixel. It is possible that a similar mechanism might be used in the human visual system.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 1432-0770Source: Springer Online Journal Archives 1860-2000Topics: BiologyComputer SciencePhysicsNotes: Abstract The Generalized Hebbian Algorithm has been proposed for training linear feedforward neural networks and has been proven to cause the weights to converge to the eigenvectors of the input distribution (Sanger 1989a, b). For an input distribution given by 2D Gaussian smoothed white noise inside a Gaussian window, some of the masks learned by the Generalized Hebbian Algorithm resemble edge and bar detectors. Since these do not match the form of the actual eigenvectors of this distribution (Linsker 1987, 1990), we seek an explanation of the development of the masks prior to complete convergence to the correct solution. Analysis in the spatial and spatial frequency domains sheds light on this development, and shows that the masks which occur tend to be localized in the spatial frequency domain, reminiscent of one of the properties of 2D Gabor filters proposed by Daugman ( 1980, 1985) as a model for the receptive fields of cells in primate visual cortex.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesBeasley, C. M. ; Sanger, T. ; Satterlee, W. ; Tollefson, G. ; Tran, P. ; Hamilton, S.
Springer
Published 1996Staff ViewISSN: 1432-2072Keywords: Olanzapine ; Placebo ; Acute ; Double-blind ; Atypical ; Schizophrenia ; AntipsychoticSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Olanzapine is a potential new “atypical” antipsychotic agent. This double-blind, acute phase study compared two doses of olanzapine [1 mg/day (Olz1.0); 10 mg/day (Olz10.0)] with placebo in the treatment of 152 patients who met the DSM-III-R criteria for schizophrenia and had a Brief Psychiatric Rating Scale (BPRS)-total score (items scored 0–6) ≥24. In overall symptomatology improvement [BPRS-total score and Positive and Negative Syndrome Scale (PANSS)-total score], Olz10.0 was statistically significantly superior to placebo. In positive symptom improvement (PANSS-positive score, BPRS-positive score), Olz10.0 was statistically significantly superior to placebo. In negative symptom improvement (PANSS-negative score), Olz10.0 was statistically superior to placebo. Olz 1.0 was clinically comparable to placebo in all efficacy comparisons. The only adverse event to show an overall statistically significant incidence difference was anorexia (reported for 10% of placebo-treated and 0% of Olz10.0-treated patients). The Olz10.0-treated patients improved over baseline with respect to parkinsonian and akathisia symptoms, and these changes were comparable with those observed with placebo. There were no dystonias associated with Olz10.0 treatment. At endpoint, the incidence of patients with elevated prolactin values did not differ statistically significantly between placebo-treated and Olz10.0-treated patients. Olanzapine appears to be not only safe and effective, but a promising atypical antipsychotic candidate.Type of Medium: Electronic ResourceURL: