Search Results - (Author, Cooperation:T. Rauch)
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1Latest Papers from Table of Contents or Articles in PressH. M. Boffin ; B. Miszalski ; T. Rauch ; D. Jones ; R. L. Corradi ; R. Napiwotzki ; A. C. Day-Jones ; J. Koppen
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-11-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 0016-7185Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeographyType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 0016-7185Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeographyType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0030-4018Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1435-1463Keywords: Atropine sulfate ; spatial retention ; Morris water maze ; ratSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Twelve rats were trained to learn the location of a spatially fixed platform hidden in a Morris water maze. Asymptotic performance was achieved over six training days (10 trials/day). Then retention of the spatial task was assessed 30 min after treatment with 5, 25, 50, 75, or 100 mg/kg, ip, atropine sulfate or the equivalent volume of saline. There was a significant drug effect on escape latency, swim distance, swim speed and swim path measures of spatial performance. There was no significant drug effect on heading error; atropinized animals initially headed toward the escape platform over the first 12 cm of their swim path. However, treatment with atropine sulfate significantly disrupted the usual, direct swim path used to reach the hidden escape platform. Atropinized animals frequently swam a spiraled or looping pattern to locate the platform. We suggest that cholinergic blockade may significantly disrupt the processing of visual cues which rats use in place navigation tasks.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1435-1463Keywords: Atropine ; spatial retention ; dose-responseSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Retention of a well-learned spatial task was assessed in rats 10 minutes prior to, and 10, 20, 30, 40, and 50 minutes after treatment with 3, 10 or 30 mg/kg, iv, atropine sulfate or the equivalent volume of saline, iv. There was a variable dose effect for escape latency and choice accuracy measures of spatial retention. A relatively large dose of atropine sulfate (30 mg/kg, iv) significantly impaired choice accuracy and escape latency compared with the control group. Moreover, impairment in choice accuracy was observed with smaller doses of atropine sulfate (3, 10mg/kg, iv) than have previously been shown to disrupt spatial retention.Type of Medium: Electronic ResourceURL: