Search Results - (Author, Cooperation:T. Nakano)
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1A. Tsuchiyama ; M. Uesugi ; T. Matsushima ; T. Michikami ; T. Kadono ; T. Nakamura ; K. Uesugi ; T. Nakano ; S. A. Sandford ; R. Noguchi ; T. Matsumoto ; J. Matsuno ; T. Nagano ; Y. Imai ; A. Takeuchi ; Y. Suzuki ; T. Ogami ; J. Katagiri ; M. Ebihara ; T. R. Ireland ; F. Kitajima ; K. Nagao ; H. Naraoka ; T. Noguchi ; R. Okazaki ; H. Yurimoto ; M. E. Zolensky ; T. Mukai ; M. Abe ; T. Yada ; A. Fujimura ; M. Yoshikawa ; J. Kawaguchi
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2H. Suga ; T. Kadoshima ; M. Minaguchi ; M. Ohgushi ; M. Soen ; T. Nakano ; N. Takata ; T. Wataya ; K. Muguruma ; H. Miyoshi ; S. Yonemura ; Y. Oiso ; Y. Sasai
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-11-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Culture Techniques ; Cell Line ; Cell Lineage ; Cells, Cultured ; Ectoderm/cytology/embryology ; Embryonic Stem Cells/*cytology ; Endocrine Cells/cytology/metabolism ; Hypopituitarism/pathology ; Hypothalamus/cytology/embryology ; Mice ; Pituitary Gland, Anterior/*cytology/*embryologyPublished by: -
3T. Watanabe ; S. Tomizawa ; K. Mitsuya ; Y. Totoki ; Y. Yamamoto ; S. Kuramochi-Miyagawa ; N. Iida ; Y. Hoki ; P. J. Murphy ; A. Toyoda ; K. Gotoh ; H. Hiura ; T. Arima ; A. Fujiyama ; T. Sado ; T. Shibata ; T. Nakano ; H. Lin ; K. Ichiyanagi ; P. D. Soloway ; H. Sasaki
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-05-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Argonaute Proteins ; *DNA Methylation ; *Genomic Imprinting ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondrial Proteins/genetics/metabolism ; Models, Genetic ; Mutation ; Phospholipase D/genetics/metabolism ; Proteins/genetics/metabolism ; RNA, Small Interfering/*genetics/metabolism ; RNA, Untranslated/*genetics/metabolism ; Repetitive Sequences, Nucleic Acid ; Retroelements ; Spermatogonia/metabolism ; Testis/embryology/metabolism ; Transcription, Genetic ; ras-GRF1/*geneticsPublished by: -
4R. Okumura ; T. Kurakawa ; T. Nakano ; H. Kayama ; M. Kinoshita ; D. Motooka ; K. Gotoh ; T. Kimura ; N. Kamiyama ; T. Kusu ; Y. Ueda ; H. Wu ; H. Iijima ; S. Barman ; H. Osawa ; H. Matsuno ; J. Nishimura ; Y. Ohba ; S. Nakamura ; T. Iida ; M. Yamamoto ; E. Umemoto ; K. Sano ; K. Takeda
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Adhesion ; Caco-2 Cells ; Cell Line ; Colitis/chemically induced/drug therapy/genetics ; Colon/*microbiology ; Dextran Sulfate ; Epithelium/*microbiology ; Female ; *Flagella ; GPI-Linked Proteins/deficiency/genetics/*metabolism/secretion ; Gram-Negative Bacteria/drug effects/metabolism/pathogenicity/*physiology ; Homeostasis ; Humans ; Inflammation/chemically induced/drug therapy/genetics ; Intestinal Mucosa/cytology/metabolism/*microbiology/secretion ; Male ; Mice ; Proteus mirabilis/drug effects/metabolism/pathogenicity ; SymbiosisPublished by: -
5T. Nakamura ; Y. J. Liu ; H. Nakashima ; H. Umehara ; K. Inoue ; S. Matoba ; M. Tachibana ; A. Ogura ; Y. Shinkai ; T. Nakano
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 5-Methylcytosine/*metabolism ; Animals ; Chromatin/chemistry/metabolism ; Cytosine/*analogs & derivatives/metabolism ; DNA Methylation ; DNA-Binding Proteins/metabolism ; Embryo, Mammalian/embryology/*metabolism ; Embryonic Development ; Female ; Genomic Imprinting/genetics ; Histones/*chemistry/*metabolism ; Lysine/chemistry/metabolism ; Male ; Methylation ; Mice ; Protein Binding/drug effects ; Proto-Oncogene Proteins/metabolism ; RNA, Long Noncoding ; RNA, Untranslated/genetics ; Repressor Proteins/*metabolism ; Spermatozoa/metabolism ; ras-GRF1/geneticsPublished by: -
6Pearton, S. J. ; Nakano, T. ; Gottscho, R. A.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The average electron densities in CH4/H2/Ar and CCl2F2/O2 electron cyclotron resonance discharges typical of those used for etching InP, GaAs, and related materials have been measured approximately 4 cm downstream from the multipolar microwave source as a function of microwave power (50–300 W), additional radio-frequency power (10–50 W), pressure (1–20 mTorr), flow rate (30–90 standard cubic centimeters per minute) and gas composition. At 1 mTorr pressure and 10 W rf, the electron densities (and semiconductor etch rates) increase rapidly with microwave power, from 1.3×1011 cm−3 for 5CH4/17H2/8Ar and 6×1010 cm−3 for 28CCl2F2/2O2 discharges at 50-W microwave power, to 9×1011 cm−3 and 3×1011 cm−3, respectively at 300-W microwave power. At the highest microwave power levels (≥200 W) the InP and GaAs etched surface morphologies are rough due to preferential removal of one of the lattice constituents from each material. The electron densities in both types of discharge show moderate increases with increasing rf power level, pressure or higher Ar or O concentrations.Type of Medium: Electronic ResourceURL: -
7Multifractality in edge localized modes in Japan Atomic Energy Research Institute Tokamak-60 UpgradeBak, P. E. ; Asakura, N. ; Miura, Y. ; Nakano, T. ; Yoshino, R.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The temporal losses of confinement during edge localized modes in the Japan Atomic Energy Research Institute Tokamak-60 Upgrade (JT-60U) show multifractal scaling and the spectra are generally smooth, but in some cases there are signs of discontinuous derivatives. Dynamics of the Sugama–Horton model, interpreted as edge localized modes, also display multifractal scaling. The spectra display singularities in the derivative, which can be interpreted as a phase transition. It is argued that the multifractal spectra of edge localized modes can be used to discriminate between different experimental discharges and validate edge localized mode models. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
8Izumi, N. ; Yamaguchi, K. ; Yamagajo, T. ; Nakano, T. ; Kasai, T. ; Urano, T. ; Azechi, H. ; Nakai, S.
[S.l.] : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: We have developed the highly efficient neutron detector system MANDALA for the inertial-confinement-fusion experiment. The MANDALA system consists of 842 elements plastic scintillation detectors and data acquisition electronics. The detection level is the yield of 1.2×105 for 2.5 MeV and 1×105 for 14.1 MeV neutrons (with 100 detected hits). We have calibrated the intrinsic detection efficiencies of the detector elements using a neutron generator facility. Timing calibration and integrity test of the system were also carried out with a 60Co γ ray source. MANDALA system was applied to the implosion experiments at the GEKKO XII laser facility. The integrity test was carried out by implosion experiments. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The highly sensitive field sensor with a Pockels crystal which was devised by us has been modified by using a light reflection technique. By replacing a metallic mirror with a dielectric mirror which is sputtered on one end face of the Pockels crystal, the new field measuring system has an advantage of precisely measuring the field distribution in the long gap discharge. This is the case when the field sensing part consisting of the Pockels crystal is isolated from the main field measuring system and both are connected to each other with a long light guide cable. Based on our experiments, we found that the measurable minimum field strength in the long gap discharge is 2 V/cm with the accuracy of 16 dB and 0.2 V/cm with the critical accuracy of 0 dB. Furthermore, we point out that the size of the field sensing part can be reduced down to 1 mm in diameter by using a dielectric mirror and a light guide cable.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: The total activities of monoamine oxidase (MAO) and the ratio of type B/type A activities were determined in mouse neuroblastoma N1E-115 cells, and in NX31T and NG108-15 hybrid cells derived from mouse neuroblastoma × rat sympathetic ganglion hybrid or mouse neuroblastoma × rat glioma hybrid cells. N1E-115 and NX31T cells possessed type A activities exclusively, although NG108-15 cells showed both type A (65–90%) and type B (10–35%) MAO activities. The activity of type A MAO in NX31T and N1E-115 cells was relatively constant during culturing periods in the presence or absence of dibutyryl cyclic AMP (Bt2cAMP), whereas total MAO activity and the ratio of type B MAO/type A MAO in NG108-15 cells increased as a function of culture periods. Prostaglandin E1 (PGE1) and theophylline, the best known combination to increase intracellular cyclic AMP content of NG108-15 cells, caused similar increases of MAO and of the type B/type A ratio in NG108-15 cells. The results suggest that MAO activity and expression of MAO B activity are regulated in NG108-15 cells in a cyclic AMP-dependent manner.Type of Medium: Electronic ResourceURL: -
11Tominaga, J. ; Nakano, T. ; Atoda, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A technique for recording and retrieving small marks beyond the optical diffraction limit was proposed. The basic experiment with this technique was also carried out at a constant linear velocity of 2.0 m/s, rotating a disk with a multi-layered structure of Sb and GeSbTe, which were separated by a thin film of SiN. By use of the optically nonlinear property of the Sb thin film, carrier to noise ratio of more than 10 dB was obtained from recorded marks of 90 nm, using an optical system with the laser wavelength of 686 nm and a numerical aperture of 0.6. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Shimomura, T ; Kowa, H ; Nakano, T ; Kitano, A ; Marukawa, H ; Urakami, K ; Takahashi, K
USA/Oxford, UK : American Association for the Study of Headache/Blackwell Science Ltd
Published 1994Staff ViewISSN: 1468-2982Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Superoxide dismutase (SOD) is a radical-scavenging enzyme. We determined Cu, Zn-SOD concentrations and activities in platelets from subjects with migraine and tension-type headaches. Thirty migraine without aura (MWoA) patients, 9 migraine with aura (MWA) patients, and 53 tension-type headache patients were selected for study. Thirty healthy volunteers composed the control group. Concentrations of platelet SOD were determined using enzyme-linked immunosorbent assay techniques. The activity of platelet SOD was determined by measuring reductivity of nitroblue tetrazolium. Low concentrations of platelet SOD were found in patients with MWA and MWoA. Platelet SOD activity decreased in MWA patients but not in patients with MWoA or tension-type headaches. These findings suggest vulnerability to oxidative stress in patients with migraine. It is suggested that low platelet SOD levels may play an important role in the etiology of migraine.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: In order to find appropriate diffusion barrier materials for Cu, the diffusion of Cu into Si through various barrier metals M (M=Cr, Ti, Nb, Mo, Ta, W) was investigated. The behavior of Cu in Cu/M/Si multilayers was measured after annealing using x-ray diffraction analysis, secondary ion mass spectroscopy, Rutherford backscattering spectroscopy, and electric resistance change. Only Cu/Ta/Si and Cu/W/Si multilayers retained their multilayer structures after annealing at 600 °C×1 h in H2 without resistivity increases. Multilayers of the other metals did not retain their structures after the same annealing condition. This difference in the barrier properties of the transition metals appeared to be related to the metal-Cu binary phase diagrams and their self-diffusion coefficients.Type of Medium: Electronic ResourceURL: -
14Kim, J. H. ; Buechel, D. ; Nakano, T. ; Tominaga, J. ; Atoda, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Magneto-optical (MO) recording signals were enhanced by a nonmagnetic mask layer combining a silver oxide (AgOx) thin film and near-field coupled super-resolution. The signal intensity of 300 nm marks recorded by a 680 nm laser and a lens numerical aperture of 0.55 with light-intensity modulation was amplified 100 times in comparison with conventional MO media. Resolution of less than 200 nm was achieved by near-field coupling between a light-scattering center generated in the AgOx film and light polarization of MO marks. To identify near-field enhancement, we simulated electrical field components, finding that near-field coupling between the light-scattering center and a MO layer enhances MO signals about 20 times due to the surface plasmon effect. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
15Tominaga, J. ; Mihalcea, C. ; Büchel, D. ; Fukuda, H. ; Nakano, T. ; Atoda, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A proposal for a photonic transistor is made and some basic proving experiments are described. These experiments show that by focusing two laser beams (405 and 635 nm) in one small spot on a high-speed rotating optical disk, a large signal enhancement is observed. It was found that a plasmon interaction generated between a silver light-scattering center and recorded small marks in the optical disk with a super-resolution near-field structure produced the large signal amplification in the spot (〈1 μm). A modulated signal of the blue laser was enhanced by 60 times by controlling the red laser power from 1.5 to 3.5 mW. It has been shown that the system has the potential to realize all-thin-films photonic transistors by using local plasmon amplification. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The sensitivity of an optical field sensor with a Pockels crystal of LiNbO3 for measuring a field distribution in a long-gap discharge has been much improved by using an intensity difference method with an intensity-modulated laser beam. The signal-to-noise ratio (S/N) is also improved by 37 dB from that without the above-mentioned method. The resultant sensitivity of the new field measuring system is 100 times higher than that of the previous one. Finally, it is possible to measure an electric field down to 7.5 V/cm in the long-gap discharge with high accuracy corresponding to the S/N ratio of 20 dB and 1.5 V/cm with the accuracy of 6.0 dB.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Glutathione peroxidase (GSH-Px) activity was detected in the muscle and skin tissues from several fish species. The muscle GSH-Px showed an optimum pH at 8.0 for salmon and 8.5 for carp. Stability of salmon muscle enzyme was enhanced in the presence of reduced glutathione (GSH), but considerably decreased in the presence of tert-butylhydroperoxide. When salmon fillets were stored at -50°C, the GSH-Px activity increased gradually during storage. Fish muscle GSH-Px shows potential for preventing oxidative deterioration in muscle during storage and processing.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Superoxide dismutase (SOD) activity in the skin of fish was observed to be higher in the dark than in the light parts. SOD activities in both parts were confirmed by visualisation of SOD activity on polyacrylamide gels. We suggest that the distribution of higher SOD in the dark parts of the skin might be related to melanization and to regulate of reactive oxygen species.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: : Glycomacropeptide (GMP) was purified from chymosin-hydrolyzed caseinate solution by the procedure involving: (1) gel chromatography on Sephacryl S-200 at pH 7.0 to obtain a crude GMP fraction; (2) addition of acidic solution, pH 3.5 to the crude glycomacropeptide to precipitate contaminating protein and/or peptide; and (3) re-chromatography of the material soluble in the acidic solution on Sephacryl S-200 at pH 3.5. The purified GMP accounted for 5.3% of dry weight of caseinate hydrolysate, and 0.7% of dry weight of sodium caseinate powder. The preparation was of considerably high purity with its amino-acid composition showing only traces (each 〈 1 residue / peptide) of arginine, histidine, phenylalanine, and tyrosine, the amino acids that do not occur in GMP.Type of Medium: Electronic ResourceURL: -
20Oka, K. ; Tkalcevic, G.T. ; Nakano, T. ; Tucker, H. ; Ishimura-Oka, K. ; Brown, W.V.
Amsterdam : ElsevierStaff ViewISSN: 0167-4781Keywords: (Human) ; Gene structure ; Lipoprotein lipase ; Polymorphic mapSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: