Search Results - (Author, Cooperation:T. Nakamura)
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1Kurihara-Shimomura, M., Sasahira, T., Nakamura, H., Nakashima, C., Kuniyasu, H., Kirita, T.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-04-19Publisher: BMJ Publishing GroupPrint ISSN: 0021-9746Electronic ISSN: 1472-4146Topics: MedicinePublished by: -
2Staff View
Publication Date: 2018-03-14Publisher: Oxford University PressPrint ISSN: 1367-4803Electronic ISSN: 1460-2059Topics: BiologyComputer ScienceMedicinePublished by: -
3Umemoto, T., Hashimoto, M., Matsumura, T., Nakamura-Ishizu, A., Suda, T.
Rockefeller University Press
Published 2018Staff ViewPublication Date: 2018-08-07Publisher: Rockefeller University PressPrint ISSN: 0022-1007Electronic ISSN: 1540-9538Topics: MedicineKeywords: Stem Cells & RegenerationPublished by: -
4O. P. Popova ; P. Jenniskens ; V. Emel'yanenko ; A. Kartashova ; E. Biryukov ; S. Khaibrakhmanov ; V. Shuvalov ; Y. Rybnov ; A. Dudorov ; V. I. Grokhovsky ; D. D. Badyukov ; Q. Z. Yin ; P. S. Gural ; J. Albers ; M. Granvik ; L. G. Evers ; J. Kuiper ; V. Kharlamov ; A. Solovyov ; Y. S. Rusakov ; S. Korotkiy ; I. Serdyuk ; A. V. Korochantsev ; M. Y. Larionov ; D. Glazachev ; A. E. Mayer ; G. Gisler ; S. V. Gladkovsky ; J. Wimpenny ; M. E. Sanborn ; A. Yamakawa ; K. L. Verosub ; D. J. Rowland ; S. Roeske ; N. W. Botto ; J. M. Friedrich ; M. E. Zolensky ; L. Le ; D. Ross ; K. Ziegler ; T. Nakamura ; I. Ahn ; J. I. Lee ; Q. Zhou ; X. H. Li ; Q. L. Li ; Y. Liu ; G. Q. Tang ; T. Hiroi ; D. Sears ; I. A. Weinstein ; A. S. Vokhmintsev ; A. V. Ishchenko ; P. Schmitt-Kopplin ; N. Hertkorn ; K. Nagao ; M. K. Haba ; M. Komatsu ; T. Mikouchi
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-11-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Accidents ; *Air ; *Explosions ; *Meteoroids ; RussiaPublished by: -
5A. R. Forrest ; H. Kawaji ; M. Rehli ; J. K. Baillie ; M. J. de Hoon ; V. Haberle ; T. Lassmann ; I. V. Kulakovskiy ; M. Lizio ; M. Itoh ; R. Andersson ; C. J. Mungall ; T. F. Meehan ; S. Schmeier ; N. Bertin ; M. Jorgensen ; E. Dimont ; E. Arner ; C. Schmidl ; U. Schaefer ; Y. A. Medvedeva ; C. Plessy ; M. Vitezic ; J. Severin ; C. Semple ; Y. Ishizu ; R. S. Young ; M. Francescatto ; I. Alam ; D. Albanese ; G. M. Altschuler ; T. Arakawa ; J. A. Archer ; P. Arner ; M. Babina ; S. Rennie ; P. J. Balwierz ; A. G. Beckhouse ; S. Pradhan-Bhatt ; J. A. Blake ; A. Blumenthal ; B. Bodega ; A. Bonetti ; J. Briggs ; F. Brombacher ; A. M. Burroughs ; A. Califano ; C. V. Cannistraci ; D. Carbajo ; Y. Chen ; M. Chierici ; Y. Ciani ; H. C. Clevers ; E. Dalla ; C. A. Davis ; M. Detmar ; A. D. Diehl ; T. Dohi ; F. Drablos ; A. S. Edge ; M. Edinger ; K. Ekwall ; M. Endoh ; H. Enomoto ; M. Fagiolini ; L. Fairbairn ; H. Fang ; M. C. Farach-Carson ; G. J. Faulkner ; A. V. Favorov ; M. E. Fisher ; M. C. Frith ; R. Fujita ; S. Fukuda ; C. Furlanello ; M. Furino ; J. Furusawa ; T. B. Geijtenbeek ; A. P. Gibson ; T. Gingeras ; D. Goldowitz ; J. Gough ; S. Guhl ; R. Guler ; S. Gustincich ; T. J. Ha ; M. Hamaguchi ; M. Hara ; M. Harbers ; J. Harshbarger ; A. Hasegawa ; Y. Hasegawa ; T. Hashimoto ; M. Herlyn ; K. J. Hitchens ; S. J. Ho Sui ; O. M. Hofmann ; I. Hoof ; F. Hori ; L. Huminiecki ; K. Iida ; T. Ikawa ; B. R. Jankovic ; H. Jia ; A. Joshi ; G. Jurman ; B. Kaczkowski ; C. Kai ; K. Kaida ; A. Kaiho ; K. Kajiyama ; M. Kanamori-Katayama ; A. S. Kasianov ; T. Kasukawa ; S. Katayama ; S. Kato ; S. Kawaguchi ; H. Kawamoto ; Y. I. Kawamura ; T. Kawashima ; J. S. Kempfle ; T. J. Kenna ; J. Kere ; L. M. Khachigian ; T. Kitamura ; S. P. Klinken ; A. J. Knox ; M. Kojima ; S. Kojima ; N. Kondo ; H. Koseki ; S. Koyasu ; S. Krampitz ; A. Kubosaki ; A. T. Kwon ; J. F. Laros ; W. Lee ; A. Lennartsson ; K. Li ; B. Lilje ; L. Lipovich ; A. Mackay-Sim ; R. Manabe ; J. C. Mar ; B. Marchand ; A. Mathelier ; N. Mejhert ; A. Meynert ; Y. Mizuno ; D. A. de Lima Morais ; H. Morikawa ; M. Morimoto ; K. Moro ; E. Motakis ; H. Motohashi ; C. L. Mummery ; M. Murata ; S. Nagao-Sato ; Y. Nakachi ; F. Nakahara ; T. Nakamura ; Y. Nakamura ; K. Nakazato ; E. van Nimwegen ; N. Ninomiya ; H. Nishiyori ; S. Noma ; T. Noazaki ; S. Ogishima ; N. Ohkura ; H. Ohimiya ; H. Ohno ; M. Ohshima ; M. Okada-Hatakeyama ; Y. Okazaki ; V. Orlando ; D. A. Ovchinnikov ; A. Pain ; R. Passier ; M. Patrikakis ; H. Persson ; S. Piazza ; J. G. Prendergast ; O. J. Rackham ; J. A. Ramilowski ; M. Rashid ; T. Ravasi ; P. Rizzu ; M. Roncador ; S. Roy ; M. B. Rye ; E. Saijyo ; A. Sajantila ; A. Saka ; S. Sakaguchi ; M. Sakai ; H. Sato ; S. Savvi ; A. Saxena ; C. Schneider ; E. A. Schultes ; G. G. Schulze-Tanzil ; A. Schwegmann ; T. Sengstag ; G. Sheng ; H. Shimoji ; Y. Shimoni ; J. W. Shin ; C. Simon ; D. Sugiyama ; T. Sugiyama ; M. Suzuki ; N. Suzuki ; R. K. Swoboda ; P. A. t Hoen ; M. Tagami ; N. Takahashi ; J. Takai ; H. Tanaka ; H. Tatsukawa ; Z. Tatum ; M. Thompson ; H. Toyodo ; T. Toyoda ; E. Valen ; M. van de Wetering ; L. M. van den Berg ; R. Verado ; D. Vijayan ; I. E. Vorontsov ; W. W. Wasserman ; S. Watanabe ; C. A. Wells ; L. N. Winteringham ; E. Wolvetang ; E. J. Wood ; Y. Yamaguchi ; M. Yamamoto ; M. Yoneda ; Y. Yonekura ; S. Yoshida ; S. E. Zabierowski ; P. G. Zhang ; X. Zhao ; S. Zucchelli ; K. M. Summers ; H. Suzuki ; C. O. Daub ; J. Kawai ; P. Heutink ; W. Hide ; T. C. Freeman ; B. Lenhard ; V. B. Bajic ; M. S. Taylor ; V. J. Makeev ; A. Sandelin ; D. A. Hume ; P. Carninci ; Y. Hayashizaki
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-03-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Atlases as Topic ; Cell Line ; Cells, Cultured ; Cluster Analysis ; Conserved Sequence/genetics ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Genes, Essential/genetics ; Genome/genetics ; Humans ; Mice ; *Molecular Sequence Annotation ; Open Reading Frames/genetics ; Organ Specificity ; Promoter Regions, Genetic/*genetics ; RNA, Messenger/analysis/genetics ; Transcription Factors/metabolism ; Transcription Initiation Site ; Transcription, Genetic/genetics ; Transcriptome/*geneticsPublished by: -
6A. Tsuchiyama ; M. Uesugi ; T. Matsushima ; T. Michikami ; T. Kadono ; T. Nakamura ; K. Uesugi ; T. Nakano ; S. A. Sandford ; R. Noguchi ; T. Matsumoto ; J. Matsuno ; T. Nagano ; Y. Imai ; A. Takeuchi ; Y. Suzuki ; T. Ogami ; J. Katagiri ; M. Ebihara ; T. R. Ireland ; F. Kitajima ; K. Nagao ; H. Naraoka ; T. Noguchi ; R. Okazaki ; H. Yurimoto ; M. E. Zolensky ; T. Mukai ; M. Abe ; T. Yada ; A. Fujimura ; M. Yoshikawa ; J. Kawaguchi
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
7T. Nakamura ; T. Noguchi ; M. Tanaka ; M. E. Zolensky ; M. Kimura ; A. Tsuchiyama ; A. Nakato ; T. Ogami ; H. Ishida ; M. Uesugi ; T. Yada ; K. Shirai ; A. Fujimura ; R. Okazaki ; S. A. Sandford ; Y. Ishibashi ; M. Abe ; T. Okada ; M. Ueno ; T. Mukai ; M. Yoshikawa ; J. Kawaguchi
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
8B. Lu ; T. Nakamura ; K. Inouye ; J. Li ; Y. Tang ; P. Lundback ; S. I. Valdes-Ferrer ; P. S. Olofsson ; T. Kalb ; J. Roth ; Y. Zou ; H. Erlandsson-Harris ; H. Yang ; J. P. Ting ; H. Wang ; U. Andersson ; D. J. Antoine ; S. S. Chavan ; G. S. Hotamisligil ; K. J. Tracey
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/metabolism ; Adenosine Triphosphate/pharmacology ; Animals ; Antigens, Bacterial/pharmacology ; Apoptosis Regulatory Proteins/metabolism ; Bacterial Toxins/pharmacology ; CARD Signaling Adaptor Proteins/metabolism ; Calcium-Binding Proteins/metabolism ; Carrier Proteins/metabolism ; Cell Line ; Cells, Cultured ; Crystallins/metabolism ; Escherichia coli/immunology/physiology ; Escherichia coli Infections/immunology/metabolism ; Female ; HMGB1 Protein/blood/*secretion ; Humans ; Inflammasomes/agonists/*metabolism ; Interleukin-18/blood ; Interleukin-1beta/blood ; Interleukin-6/analysis/blood ; Macrophages, Peritoneal/drug effects/metabolism ; Male ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Peritonitis/metabolism ; Phosphorylation ; RNA, Double-Stranded/immunology/pharmacology ; Rotenone/pharmacology ; Salmonella Infections/immunology/metabolism ; Salmonella typhimurium/immunology/physiology ; Transfection ; Uric Acid/pharmacology ; eIF-2 Kinase/antagonists & inhibitors/deficiency/genetics/*metabolismPublished by: -
9M. Maekawa ; K. Yamaguchi ; T. Nakamura ; R. Shibukawa ; I. Kodanaka ; T. Ichisaka ; Y. Kawamura ; H. Mochizuki ; N. Goshima ; S. Yamanaka
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-06-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Line ; Cells, Cultured ; *Cellular Reprogramming ; DNA-Binding Proteins/*metabolism ; Embryonic Stem Cells/cytology/metabolism ; Epithelial-Mesenchymal Transition ; Female ; Fibroblasts/*cytology/*metabolism ; Gene Expression Profiling ; Genes, myc/genetics ; Hepatocyte Nuclear Factor 3-beta/metabolism ; Homeodomain Proteins/metabolism ; Humans ; Induced Pluripotent Stem Cells/*cytology/*metabolism ; Mice ; Nuclear Transfer Techniques ; Oligonucleotide Array Sequence Analysis ; Protein Binding ; RNA-Binding Proteins/metabolism ; Receptors, Estrogen/metabolism ; Transcription Factors/*metabolismPublished by: -
10Staff View
Publication Date: 2012-06-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Carbon Isotopes/*analysis ; Cedrus/*chemistry ; *Cosmic Radiation ; JapanPublished by: -
11A. Bessede ; M. Gargaro ; M. T. Pallotta ; D. Matino ; G. Servillo ; C. Brunacci ; S. Bicciato ; E. M. Mazza ; A. Macchiarulo ; C. Vacca ; R. Iannitti ; L. Tissi ; C. Volpi ; M. L. Belladonna ; C. Orabona ; R. Bianchi ; T. V. Lanz ; M. Platten ; M. A. Della Fazia ; D. Piobbico ; T. Zelante ; H. Funakoshi ; T. Nakamura ; D. Gilot ; M. S. Denison ; G. J. Guillemin ; J. B. DuHadaway ; G. C. Prendergast ; R. Metz ; M. Geffard ; L. Boon ; M. Pirro ; A. Iorio ; B. Veyret ; L. Romani ; U. Grohmann ; F. Fallarino ; P. Puccetti
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-06-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Infections/immunology/metabolism ; Disease Resistance/drug effects/*genetics/*immunology ; Endotoxemia/genetics/immunology/metabolism ; Enzyme Activation/drug effects ; Gene Expression Regulation/drug effects ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Inflammation/enzymology/genetics/metabolism ; Kynurenine/metabolism ; Lipopolysaccharides/pharmacology ; Mice ; Phosphorylation ; Receptors, Aryl Hydrocarbon/genetics/*metabolism ; Signal Transduction ; Tryptophan Oxygenase/metabolism ; src-Family Kinases/metabolismPublished by: -
12M. Ebihara ; S. Sekimoto ; N. Shirai ; Y. Hamajima ; M. Yamamoto ; K. Kumagai ; Y. Oura ; T. R. Ireland ; F. Kitajima ; K. Nagao ; T. Nakamura ; H. Naraoka ; T. Noguchi ; R. Okazaki ; A. Tsuchiyama ; M. Uesugi ; H. Yurimoto ; M. E. Zolensky ; M. Abe ; A. Fujimura ; T. Mukai ; Y. Yada
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
13T. Noguchi ; T. Nakamura ; M. Kimura ; M. E. Zolensky ; M. Tanaka ; T. Hashimoto ; M. Konno ; A. Nakato ; T. Ogami ; A. Fujimura ; M. Abe ; T. Yada ; T. Mukai ; M. Ueno ; T. Okada ; K. Shirai ; Y. Ishibashi ; R. Okazaki
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
14H. Yurimoto ; K. Abe ; M. Abe ; M. Ebihara ; A. Fujimura ; M. Hashiguchi ; K. Hashizume ; T. R. Ireland ; S. Itoh ; J. Katayama ; C. Kato ; J. Kawaguchi ; N. Kawasaki ; F. Kitajima ; S. Kobayashi ; T. Meike ; T. Mukai ; K. Nagao ; T. Nakamura ; H. Naraoka ; T. Noguchi ; R. Okazaki ; C. Park ; N. Sakamoto ; Y. Seto ; M. Takei ; A. Tsuchiyama ; M. Uesugi ; S. Wakaki ; T. Yada ; K. Yamamoto ; M. Yoshikawa ; M. E. Zolensky
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
15K. Nagao ; R. Okazaki ; T. Nakamura ; Y. N. Miura ; T. Osawa ; K. Bajo ; S. Matsuda ; M. Ebihara ; T. R. Ireland ; F. Kitajima ; H. Naraoka ; T. Noguchi ; A. Tsuchiyama ; H. Yurimoto ; M. E. Zolensky ; M. Uesugi ; K. Shirai ; M. Abe ; T. Yada ; Y. Ishibashi ; A. Fujimura ; T. Mukai ; M. Ueno ; T. Okada ; M. Yoshikawa ; J. Kawaguchi
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
16T. Nakamura, H. Kim, S. Ichinokura, A. Takayama, A. V. Zotov, A. A. Saranin, Y. Hasegawa, and S. Hasegawa
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-10-17Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Superfluidity and superconductivityPublished by: -
17T. Nakamura ; Y. J. Liu ; H. Nakashima ; H. Umehara ; K. Inoue ; S. Matoba ; M. Tachibana ; A. Ogura ; Y. Shinkai ; T. Nakano
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 5-Methylcytosine/*metabolism ; Animals ; Chromatin/chemistry/metabolism ; Cytosine/*analogs & derivatives/metabolism ; DNA Methylation ; DNA-Binding Proteins/metabolism ; Embryo, Mammalian/embryology/*metabolism ; Embryonic Development ; Female ; Genomic Imprinting/genetics ; Histones/*chemistry/*metabolism ; Lysine/chemistry/metabolism ; Male ; Methylation ; Mice ; Protein Binding/drug effects ; Proto-Oncogene Proteins/metabolism ; RNA, Long Noncoding ; RNA, Untranslated/genetics ; Repressor Proteins/*metabolism ; Spermatozoa/metabolism ; ras-GRF1/geneticsPublished by: -
18T. Nakamura ; Y. Zhao ; Y. Yamagata ; Y. J. Hua ; W. Yang
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Catalysis ; DNA-Directed DNA Polymerase/chemistry/*metabolism ; Humans ; Hydrogen Bonding ; Hydrogen-Ion Concentration ; Magnesium/chemistry ; Metals/chemistry ; *Models, Molecular ; Nucleic Acid Conformation ; Water/chemistryPublished by: -
19Staff View
ISSN: 1365-2842Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: summary The purpose of this study was to evaluate the stress distribution under various loading conditions within posterior all-ceramic crowns. A three-dimensional finite element model representing a lower first molar was constructed. Variations of the model had two types of single layer all-ceramic crowns (Dicor and Empress) and two types of double layer all-ceramic crowns (In-Ceram and Empress2) cemented. A load of 600 N, simulating the maximum bite force, was applied vertically to the crowns. Loads of 225 N, simulating masticatory force, were applied from three directions (vertically, at a 45° angle, and horizontally). In the test simulating maximum bite force, the maximum tensile stresses on all crowns (17·4–19·4 MPa) concentrated around the loading points. In the masticatory force simulation test, the specimens experienced maximum tensile stresses of 19·7–27·0 MPa under a horizontal load and 10·8–10·9 MPa under a vertical load. When the load was applied horizontally, the maximum tensile stress was observed around the loading points on the surface in the case of the single layer crowns, and of the cervical area of the inner core of the double layer crowns. Within the limitation of this study, it was found that the strength of occlusal contact points is important to the integrity of posterior all-ceramic crowns and that bite forces applied from the horizontal direction are a critical factor.Type of Medium: Electronic ResourceURL: -
20Nakamura, T. ; Ohyama, T. ; Imanishi, A. ; Ishigaki, S.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2842Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: summary The aim of the present study was to evaluate the mechanical strength of the Empress2 system, which is based on the use of a high-strength glass--ceramic core of lithium disilicate, and the fracture resistance of fixed partial dentures fabricated with this material. To evaluate mechanical strength, four types of ceramic materials were tested for four-point flexural strength and diametral tensile strength: Empress2 core material, Empress2 layering porcelain, conventional Empress material and Dicor. Then, using Empress2, conventional Empress and Dicor, actual clinical type anterior fixed partial dentures were fabricated for fracture testing. The results showed that the Empress2 core material, at 329 MPa, has more than twice the flexural strength of conventional materials and at 271 MPa, more than four times the diametral tensile strength of conventional materials. Furthermore, fixed partial dentures fabricated with Empress2 had a fracture resistance of 1424 N. That is, they were more than twice as fracture resistant as fixed partial dentures made with conventional materials.Type of Medium: Electronic ResourceURL: