Search Results - (Author, Cooperation:T. M. Roberts)
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1S. Jia ; Z. Liu ; S. Zhang ; P. Liu ; L. Zhang ; S. H. Lee ; J. Zhang ; S. Signoretti ; M. Loda ; T. M. Roberts ; J. J. Zhao
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-01-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2T. J. Pugh ; S. D. Weeraratne ; T. C. Archer ; D. A. Pomeranz Krummel ; D. Auclair ; J. Bochicchio ; M. O. Carneiro ; S. L. Carter ; K. Cibulskis ; R. L. Erlich ; H. Greulich ; M. S. Lawrence ; N. J. Lennon ; A. McKenna ; J. Meldrim ; A. H. Ramos ; M. G. Ross ; C. Russ ; E. Shefler ; A. Sivachenko ; B. Sogoloff ; P. Stojanov ; P. Tamayo ; J. P. Mesirov ; V. Amani ; N. Teider ; S. Sengupta ; J. P. Francois ; P. A. Northcott ; M. D. Taylor ; F. Yu ; G. R. Crabtree ; A. G. Kautzman ; S. B. Gabriel ; G. Getz ; N. Jager ; D. T. Jones ; P. Lichter ; S. M. Pfister ; T. M. Roberts ; M. Meyerson ; S. L. Pomeroy ; Y. J. Cho
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cerebellar Neoplasms/classification/*genetics ; Child ; DEAD-box RNA Helicases/chemistry/genetics/metabolism ; DNA Helicases/chemistry/genetics ; DNA-Binding Proteins/genetics ; Exome/*genetics ; Genome, Human/*genetics ; Hedgehog Proteins/metabolism ; Histone-Lysine N-Methyltransferase/genetics/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; LIM Domain Proteins/genetics ; Medulloblastoma/classification/*genetics ; Models, Molecular ; Mutation/*genetics ; Neoplasm Proteins/genetics ; Nuclear Proteins/chemistry/genetics ; Promoter Regions, Genetic/genetics ; Protein Structure, Tertiary/genetics ; Proto-Oncogene Proteins/genetics ; Receptors, Cell Surface/genetics ; Repressor Proteins/genetics ; Signal Transduction ; TCF Transcription Factors/metabolism ; Transcription Factors/chemistry/genetics ; Tumor Suppressor Protein p53/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics/metabolismPublished by: -
3ROBERTS, T. M. ; TUTTLE, R. C. ; ALLEN, J. R. ; LOEBLICH, A. R. ; KLOTZ, L. C.
[s.l.] : Nature Publishing Group
Published 1974Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] These chromosome properties immediately suggest three simple models for nuclear DNA organisation: (1) a normal pattern of alternation of haploid and diploid generations with each haploid chromosome non-identical; (2) polyploidy, having three or more sets of homologous chromosomes and (3) polyteny, ...Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Simple techniques have been used to monitor the non-ferrous metal content of the air in South-West Wales. Metal concentrations downwind of the Swansea urban-industrial complex are found to be significantly greater than the normal ...Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Any environmental factor that has an adverse effect on plant growth may exert selection pressure on plant populations by acting on their inherent genetic variability, thus causing major changes in gene frequency within a few years1. Recent research has shown the detrimental effect of SO2 on ...Type of Medium: Electronic ResourceURL: -
6CANTLEY, L. C. ; WHITMAN, M. ; CHAHWALA, S. ; FLEISCHMAN, L. ; KAPLAN, D. R. ; SCHAFFHAUSEN, B. S. ; ROBERTS, T. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1986Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] BLANK ET AL. REPLY-Although Hauhs and Ulrich say they provide a different view of forest decline to that which we presented in our Commentary article, we note that there are now many areas of agreement. There have been considerable changes from the earlier arguments put forward by Ulrich and ...Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] have not come to pass. Greater realism now characterizes research on the subject. FORESTS are part of the heritage and folklore of all European countries, but their emotional appeal is probably strongest in Germany. In 1981, public attention was first drawn to the deterioration of the nation's ...Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1432-1939Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary It has been suggested that the forest decline (“Neuartige Waldschäden”) seen recently in parts of West Germany is due to the direct effects of ozone combined with acid mists, rather than soil-mediated effects of acid deposition. It has been proposed that ozone (a) makes the needles of affected conifers more susceptible to leaching by acid mist and (b) damages the photosynthetic apparatus, giving rise to diminished carbohydrate reserves which reduce the ability of affected trees to replace the leached nutrients. This nutrient deficiency (especially of Ca and Mg) is a characteristic symptom of the Waldschäden, which progresses through growth decline, needle loss, and eventually death. Parts of this hypothesis were tested in a preliminary experiment in which 3-year old Pinus sylvestris (Scots pine) saplings were exposed to 4 different O3 levels, with and without acid mist (pH 3) treatment, for 56 days between July and September, 1983 in outdoor ‘solardome’ fumigation chambers. The visual symptoms observed at 〉100 μg m-3 were more characteristic of the chlorotic mottle seen on O3-affected trees in the USA than the general chlorosis of affected stands in Germany. O3 at mean concentrations of 〉200 μg m-3 for 56 days reduced the fine root biomass and accelerated the senescence of older needles, in keeping with field effects observed in Germany. However, these O3 levels increased, rather than decreased, the concentrations of most elements in the needles. Acid mist had no effect on needle concentrations, and there was no O3-acid mist interaction. O3 up to 300 μg m-3 also had no effect on the amount of ions leached from the needles, whereas acid mist increased the leaching of some ions, and again there was no interaction. The only nutritional effect of O3 was to reduce the foliar uptake of NO - 3 from the acid mist solution. An aphid infection part way through the experiment caused a large increase in leaching, particularly of K, and affected the intermediate O3 and watersprayed plants most. Caution is needed in extrapolating these results to the field, as the experiments were of short duration on young trees with fully-formed needles, growing in a soil better supplied with nutrients than field soils. Nevertheless, these preliminary results do not support the hypothesis of an O3-mediated increase in foliar leaching as the major cause of forest decline nor were the symptoms of O3-injury on Scots pine comparable with those reported in the field.Type of Medium: Electronic ResourceURL: -
10Preining, Othmar ; Ormrod, D. P. ; Golueke, Clarence G. ; Siegel, B. Z. ; Siegel, S. M. ; Roberts, T. M.
Springer
Published 1989Staff ViewISSN: 1573-2932Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringType of Medium: Electronic ResourceURL: