Search Results - (Author, Cooperation:T. L. Clemens)

Showing 1 - 5 results of 5, query time: 0.16s Refine Results
  1. 1
    Staff View
    Publication Date:
    2013-07-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult Stem Cells/*cytology/*physiology ; Animals ; Epigenesis, Genetic/genetics ; Gene Expression Regulation, Developmental ; *Genomic Imprinting ; Insulin-Like Growth Factor II/*genetics/*metabolism ; Mice ; RNA, Long Noncoding/*genetics/*metabolism ; Receptor, IGF Type 1/genetics ; Signal Transduction ; Transcriptional Activation
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Sterman, M. B. ; Clemens, T. L. ; Wenger, M. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1966
    Staff View
    ISSN:
    1469-8986
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Psychology
    Notes:
    Two psychiatric patient subgroups, defined on the basis of an extremely brief or an extremely prolonged electroencephalogram (EEG) response to cold pressor stimulation, also differ with regard to several aspects of autonomic response. The patients showing only a brief EEG desynchronization, with recovery during stimulation, also show a relatively brief autonomic response with recovery beginning during stimulation. They are specifically characterized by elevated levels of skin conductance throughout the measurement period. On the other hand, patients with prolonged EEG response show more prolonged autonomic response and are distinguished as a group by high heart rate levels. Clinical comparisons disclosed no diagnostic correlations. The rapid EEG and visceral recovery observed is discussed in terms of recently described neurophysiological mechanisms of homeostasis.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
  4. 4
    Staff View
    ISSN:
    1432-0827
    Keywords:
    1,25-Dihydroxy-vitamin D ; Calcium absorption ; Parathyroid hormone ; Bisphosphonate
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Physics
    Notes:
    Summary In 10 patients with Paget's disease of bone and 2 patients with osteoporosis, we studied the effects of hypocalcemia and hypophosphatemia induced by disodium-(3-amino-1-hydroxypropylidene)-1,-bisphosphonate (APD) treatment on the serum concentration of PTH and 1,25-dihydroxyvitamin D [1,25(OH)2D3] and on calcium absorption and balance. The fall in serum calcium and phosphate was associated with a rise in the serum concentration of PTH and 1,25(OH)2D3, coupled with increases in net calcium absorption and calcium balance. The concentration of 1,25(OH)2D3 was significantly related (P〈0.001) to the serum calcium (r=0.66), the serum phosphate (r=0.78), and the serum PTH (r=0.71), confirming the interrelated control of these parameters on 1,25(OH)2D3 production. Moreover, the rise in 1,25(OH)2D3 caused an appropriate rise in calcium absorption (r=0.74) and calcium balance (r=0.86), showing that this vitamin D metabolite contributes as a hormone to calcium homeostasis.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1612-1112
    Keywords:
    Tritiated dihydroxycholecalciferol metabolites ; Renal hydroxylase enzymes ; Sephadex LH 20 ; High-performance liquid chromatography
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    Summary A simple, reproducible method for the biological synthesis of tritiated 24,25-dihydroxycholecalciferol, 25,26-dihydroxycholecalciferol and 1,25-dihydroxycholecalciferol is described. Kidney homogenates from both vitamin D deficient and replete chicks were usedin vitro to generate these dihydroxylated metabolites using 25 (23,24-3H) hydroxycholecalciferol as the substrate. Tritiated products were purified by Sephadex LH 20 chromatography followed by high-performance liquid chromatography; the identity of each metabolite was established by chromatography with authentic crystalline preparations.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses