Search Results - (Author, Cooperation:T. Kruger)
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1Latest Papers from Table of Contents or Articles in PressD. L. Moyes ; D. Wilson ; J. P. Richardson ; S. Mogavero ; S. X. Tang ; J. Wernecke ; S. Hofs ; R. L. Gratacap ; J. Robbins ; M. Runglall ; C. Murciano ; M. Blagojevic ; S. Thavaraj ; T. M. Forster ; B. Hebecker ; L. Kasper ; G. Vizcay ; S. I. Iancu ; N. Kichik ; A. Hader ; O. Kurzai ; T. Luo ; T. Kruger ; O. Kniemeyer ; E. Cota ; O. Bader ; R. T. Wheeler ; T. Gutsmann ; B. Hube ; J. R. Naglik
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Calcium/metabolism ; Candida albicans/immunology/*metabolism/*pathogenicity ; Candidiasis/metabolism/microbiology/pathology ; Cell Membrane Permeability/drug effects ; Cytotoxins/genetics/*metabolism/secretion/toxicity ; Epithelial Cells/drug effects/immunology/pathology ; Fungal Proteins/genetics/metabolism/secretion/*toxicity ; Host-Pathogen Interactions/immunology ; Humans ; Mucous Membrane/microbiology/pathology ; Mycotoxins/genetics/metabolism/secretion/*toxicity ; Signal Transduction/drug effects ; Virulence/drug effects ; Virulence Factors/genetics/*metabolism/toxicityPublished by: -
2Articles: DFG German National LicensesACOSTA, A. ; KRUGER, T. ; SWANSON, R. J. ; SIMMONS, K. F. ; OEHNINGER, S. ; VEECK, L. L. ; HAGUE, D. ; PLEBAN, P. ; MORSHEDI, M. ; ACKERMAN, S.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 0378-1119Keywords: 5-methylcytosine ; DNA modification ; DNA restriction ; McrA restriction ; McrBC restrictionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0039-6028Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1044-0305Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0167-2584Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1432-1351Keywords: Egg laying hormone ; Aplysia ; Binding protein ; Immunocytochemistry ; Reproductive systemSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract A protein solubilized from a membrane preparation of the gonad of Aplysia californica has been isolated by affinity chromatography, using bag cell egg-laying hormone (ELH) as the bound ligand, and partially purified and characterized by gel electrophoresis. The protein has an apparent molecular weight of 52 kDa and consists of two disulfide-linked subunits of about 30 kDa each. The protein is glycosylated and has an acidic pI. Approximately 10–15 μg of this protein can be isolated from a single ovotestis, representing less than 1% of the total protein in the gonad; but the protein could not be detected in buccal mass or body wall, tissues which do not have apparent response to ELH. Antibodies generated against this ELH-binding protein (ELHBP) were used to localize sites in the ovotestis which might contain this molecule and thus represent targets for egg-laying hormone. Immunocytochemical results indicate that the oocytes are a rich source of this protein, since their cytoplasm was the only detectable site of immunoreactivity. Whether this binding protein represents an egg-laying hormone receptor is uncertain, but its prevalence in oocytes suggests that ELH plays a signaling role on these gametes.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesEbrahim, A. ; Rienhardt, G. ; Morris, S. ; Kruger, T. F. ; Lombard, C. J. ; Merwe, J. P.
Springer
Published 1993Staff ViewISSN: 1573-7330Keywords: follicle stimulating hormone ; luteinizing hormone ; estradiol ; oocytesSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Methods One hundred eleven consecutive females with infertility due to various etiologies were investigated. Cycle day 3 serum levels of FSH, LH, and E2 were determined prior to ovulation induction with a combination of clomiphene citrate and human gonadotropins. Follicular growth was monitored ultrasonically, and when appropriate, oocytes were recruited, counted, graded, and then used, as prearranged, for either IVF or GIFT. Basal hormone levels were compared to the peak E2 concentration, the number of follicles aspirated, and the number of preovulatory oocytes recovered following drug therapy. Details of resulting pregnancies were also recorded.Abstract: Results Patients with low basal FSH levels (〈11.5 mIu/ml) yielded a higher mean number of preovulatory oocytes than those with high values (〉11.5 mIu/ml), i.e., 6.7 oocytes per cycle vs 2.5 oocytes (P 〈 0.001). In the low group 97% of cycles yielded more than three fertilizable oocytes compared to 42% in the high group (P 〈 0.5). There were 16 term pregnancies (16%) in the low group and 1 (8.3%) in the high group. Basal LH and E2 levels did not improve on the ability to distinguish between different populations of infertile females who responded differently to ovulation induction.Notes: Aim To determine the value of basal follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) levels on cycle day 3 in predicting the ovulation stimulation response in patients receiving exogenous gonadotropins for in vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT).Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesKruger, T. F. ; Stander, F. S. H. ; Smith, K. ; Merwe, J. P. ; Lombard, C. J.
Springer
Published 1987Staff ViewISSN: 1573-7330Keywords: human in vitro fertilization ; Ham's F-10 medium ; fertilization ; embryo developmentSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The effect of serum supplementation was evaluated on 108 oocytes obtained from 29 patients. The oocytes were all mature and randomly distributed in two groups. Each ovum was paired with another ovum within the same patient. The experimental group contained no serum in the insemination and growth medium, but in the control group 10% serum was added to the insemination and growth medium. In the experimental group the cleavage rate was 66.7%, compared to 83.3% in the control group. The embryos from each patient were individually evaluated. The sign test was used for statistical analysis. A significant difference between the two groups (P=0.01) indicated that in this study the addition of serum to the medium gives better cleavage results. The effect of serum on embryos is discussed, as well as the practical implications of this finding.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1573-7330Keywords: assisted reproduction ; gonadotropin releasing hormone (GnRHa) ; gamete intrafallopian transfer (GIFT) ; human menopausal gonadotropin (hMG) ; in vitro fertilization (IVF) ; clomiphene citrate ; contraceptive pill ; ovulation inductionSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Results The overall pregnancy rate was 21.6% (11/51) in the study group and 47% (24/51) in the control group (P =0.01). However, the ongoing pregnancy rate in the two groups did not differ significantly, 11.8% (6/51) vs 27.5% (14/51) (P =0.08). In the study group, 7.8% of patients had to be seen over a weekend, compared to 13.7% in the control group (not significant).Abstract: Conclusion From the findings we conclude that, although this method of controlling cycles can be useful in selected patients, it is not the ultimate method.Notes: Purpose It may sometimes be necessary to regulate cycles in assisted reproduction. Cycles can be regulated with gonadotropin releasing hormone (GnRHa) agonist but other methods can also be used. The aim of this study was to compare the pregnancy rate in a gamete intrafallopian transfer (GIFT) program in patients receiving a contraceptive pill/Clomid/human menopausal gonadotropin (hMG) regimen (study group), with the standard Clomid/hMG regime (control group). Fifty one patients in the study group were carefully matched for patient age, infertility diagnosis (female), semen parameters, number of follicles, and number of oocytes transferred into consideration with a control group.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Both positive ion and negative ion chemical ionization mass spectra of hydroxycarboxylic acids (hydroxyethanoic acid, 3-hydroxypropanic acid, 2-hydroxypropanoic acid and 1-phenyl-1-hydroxyethanoic acid) show intense oligomeric ions when the samples are evaporated into a chemical ionization source. The observation of oligomeric anionic and cationic species is unusual, and the parallel behavior observed between the positive and negative ion mass spectra is striking. These results are explicable in terms of evaporation of oligomers and their dehydration products from the hot probe, although gas phase clustering reactions of singly charged ions are not excluded. Hydrogen bonding and dehydration provide bonding within each cluster. The structures of the ions have been confirmed by recording the collision induced dissociations of individual cluster ions via their mass analyzed ion kinetic energy spectra. Temperature dependence of the chemical ionization mass spectra provides a method for distinguishing hydrogen bonding from covalent bonding and gives further structural information on the cluster ions.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesCameron, D. ; Clark, J. E. ; Kruger, T. L. ; Cooks, R. G.
Chichester : Wiley-Blackwell
Published 1977Staff ViewISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The ion [C3H5]+ generated in a chemical ionization source by a variety of methods, including protonation and charge exchange, exhibits a metastable peak for H2 loss which is two orders of magnitude weaker than that formed in an electron impact source. The stable [C3H5]+ ions generated by electron impact and chemical ionization undergo collision-induced dissociation to a comparable extent, both losing H2 by only one of the two competitive mechanisms observed for metastable ions. In contrast to the behavior of [C3H5]+, the molecular ions of p-substituted nitrobenzene, generated by charge exchange at high source pressure, yield composite metastable peaks for NO loss which are very similar in shape and intensity to those generated by electron impact. The contrasting behavior of the metastable ions extracted from high pressure ion sources in the two systems may be due to differences in the efficiencies of quenching of the ionic states responsible for fragmentation as metastable ions. It is noteworthy that the NO loss reactions require considerably lower activation energies than does the H2 loss reaction.Additional Material: 2 Ill.Type of Medium: Electronic ResourceURL: