ILSE | Search Results - (Author, Cooperation:T. Kadowaki)

1

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

M. Okada-Iwabu ; T. Yamauchi ; M. Iwabu ; T. Honma ; K. Hamagami ; K. Matsuda ; M. Yamaguchi ; H. Tanabe ; T. Kimura-Someya ; M. Shirouzu ; H. Ogata ; K. Tokuyama ; K. Ueki ; T. Nagano ; A. Tanaka ; S. Yokoyama ; T. Kadowaki
Nature Publishing Group (NPG)
Published 2013

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Publication Date:	2013-11-01
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Adenylate Kinase/metabolism ; Adiponectin/metabolism/pharmacology ; Adipose Tissue, White/drug effects/metabolism/pathology ; Administration, Oral ; Animals ; Diabetes Mellitus, Type 2/complications/drug therapy/metabolism/prevention & ; control ; Diet, High-Fat ; Drug Evaluation, Preclinical ; Dyslipidemias/drug therapy ; Enzyme Activation/drug effects ; Glucose Intolerance/drug therapy ; Inflammation/drug therapy ; Insulin Resistance ; Liver/drug effects/metabolism/pathology ; Longevity/drug effects ; Mice ; Mitochondria/drug effects/metabolism ; Muscle Fibers, Skeletal/cytology/drug effects ; Muscles/cytology ; Obesity/complications/drug therapy/genetics/physiopathology ; Oxidative Stress/drug effects ; PPAR alpha/metabolism ; Piperidines/administration & dosage/metabolism/pharmacology/therapeutic use ; Receptors, Adiponectin/*agonists/deficiency/genetics/metabolism ; Signal Transduction/drug effects ; Small Molecule Libraries/chemistry ; Transcription Factors/biosynthesis ; Triglycerides/metabolism
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

2

Ensuring success for J-NIH

T. Kadowaki
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-11-10
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Academies and Institutes/economics/organization & administration ; Biomedical Research/economics ; Budgets ; Japan
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

3

Crystal structures of the human adiponectin receptors

H. Tanabe ; Y. Fujii ; M. Okada-Iwabu ; M. Iwabu ; Y. Nakamura ; T. Hosaka ; K. Motoyama ; M. Ikeda ; M. Wakiyama ; T. Terada ; N. Ohsawa ; M. Hato ; S. Ogasawara ; T. Hino ; T. Murata ; S. Iwata ; K. Hirata ; Y. Kawano ; M. Yamamoto ; T. Kimura-Someya ; M. Shirouzu ; T. Yamauchi ; T. Kadowaki ; S. Yokoyama
Nature Publishing Group (NPG)
Published 2015

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Publication Date:	2015-04-10
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Binding Sites ; Crystallography, X-Ray ; Histidine/chemistry/metabolism ; Humans ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Receptors, Adiponectin/*chemistry/metabolism ; Structure-Activity Relationship ; Zinc/metabolism
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

4

The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis [Research Article]

Kobayashi, M., Ohsugi, M., Sasako, T., Awazawa, M., Umehara, T., Iwane, A., Kobayashi, N., Okazaki, Y., Kubota, N., Suzuki, R., Waki, H., Horiuchi, K., Hamakubo, T., Kodama, T., Aoe, S., Tobe, K., Kadowaki, T., Ueki, K.
The American Society for Microbiology (ASM)
Published 2018

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Publication Date:	2018-07-31
Publisher:	The American Society for Microbiology (ASM)
Print ISSN:	0270-7306
Electronic ISSN:	1098-5549
Topics:	Biology Medicine
Published by:	http://www.asm.org/

Latest Papers from Table of Contents or Articles in Press

5

High power cw operation over 400 mW on five-stripe phase-locked laser arrays assembled by new junction down mounting

Seiwa, Y. ; Aoyagi, T. ; Hinata, S. ; Kadowaki, T. ; Kaneno, N. ; Ikeda, K. ; Susaki, W.

[S.l.] : American Institute of Physics (AIP)
Published 1987

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ISSN:	1089-7550
Source:	AIP Digital Archive
Topics:	Physics
Notes:	The junction down mounting attached to a Si-submount with Au-Si solder has been shown to be very reliable for lasers by aging tests of 5 mW at 80° C. The thermal resistance of this junction down mounting is 30 K/W smaller than that of a junction up mounting. Output powers as high as cw 80 mW/stripe, corresponding to 400 mW, was realized without saturation with a five-stripe phase-locked laser array with an inner-stripe configuration assembled on this mounting.
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1063/1.338793

Articles: DFG German National Licenses

6

Das Faktum der reinen praktischen Vernunft

Kadowaki, T.

Berlin : Periodicals Archive Online (PAO)
Published 1966

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ISSN:	0022-8877
Topics:	Philosophy
URL:	http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:0171-1966-056-03-000012

Articles: DFG German National Licenses

7

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Yamauchi, T. ; Kamon, J. ; Minokoshi, Y. ; Ito, Y. ; Waki, H. ; Uchida, S. ; Yamashita, S. ; Noda, M. ; Kita, S. ; Ueki, K. ; Eto, K. ; Akanuma, Y. ; Froguel, P. ; Foufelle, F. ; Ferre, P. ; Carling, D. ; Kimura, S. ; Nagai, R. ; Kahn, B.B. ; Kadowaki, T.

[s.l.] : Nature Publishing Group
Published 2002

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ISSN:	1546-170X
Source:	Nature Archives 1869 - 2009
Topics:	Biology Medicine
Notes:	[Auszug] Adiponectin (Ad) is a hormone secreted by adipocytes that regulates energy homeostasis and glucose and lipid metabolism. However, the signaling pathways that mediate the metabolic effects of Ad remain poorly identified. Here we show that phosphorylation and activation of the 5′-AMP-activated ...
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1038/nm788

Articles: DFG German National Licenses

8

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Yamauchi, T. ; Kamon, J. ; Waki, H. ; Terauchi, Y. ; Kubota, N. ; Hara, K. ; Mori, Y. ; Ide, T. ; Murakami, K. ; Tsuboyama-Kasaoka, N. ; Ezaki, O. ; Akanuma, Y. ; Gavrilova, O. ; Vinson, C. ; Reitman, M.L. ; Kagechika, H. ; Shudo, K. ; Yoda, M. ; Nakano, Y. ; Tobe, K. ; Nagai, R. ; Kimura, S. ; Tomita, M. ; Froguel, P. ; Kadowaki, T.

[s.l.] : Nature Publishing Group
Published 2001

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ISSN:	1546-170X
Source:	Nature Archives 1869 - 2009
Topics:	Biology Medicine
Notes:	[Auszug] Adiponectin is an adipocyte-derived hormone. Recent genome-wide scans have mapped a susceptibility locus for type 2 diabetes and metabolic syndrome to chromosome 3q27, where the gene encoding adiponectin is located. Here we show that decreased expression of adiponectin correlates with insulin ...
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1038/90984

Articles: DFG German National Licenses

9

A Mr=190,000 glycoprotein phosphorylated on tyrosine residues in epidermal growth factor stimulated KB cells is the product of the C-erbB-2 gene

Kadowaki, T. ; Kasuga, M. ; Tobe, K. ; Takaku, F. ; Nishida, E. ; Sakai, H. ; Koyasu, S. ; Yahara, I. ; Toyoshima, K. ; Akiyama, T. ; Yamamoto, T.

Amsterdam : Elsevier

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ISSN:	0006-291X
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Chemistry and Pharmacology Physics
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/S0006-291X(87)80021-9

Articles: DFG German National Licenses

10

Molecular Scanning of the Glycogen Synthase and Insulin Receptor Substrate-1 Genes in Japanese Subjects with Non-Insulin-Dependent Diabetes Mellitus

Shimokawa, K. ; Kadowaki, H. ; Sakura, H. ; Otabe, S. ; Hagura, R. ; Kosaka, K. ; Yazaki, Y. ; Akanuma, Y. ; Kadowaki, T.

Amsterdam : Elsevier

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ISSN:	0006-291X
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Chemistry and Pharmacology Physics
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1006/bbrc.1994.1951

Articles: DFG German National Licenses

11

Cloning of a Complete Protein-Coding Sequence of Human Platelet-Type Phosphofructokinase Isozyme from Pancreatic Islet

Eto, K. ; Sakura, H. ; Yasuda, K. ; Hayakawa, T. ; Kawasaki, E. ; Moriuchi, R. ; Nagataki, S. ; Yazaki, Y. ; Kadowaki, T.

Amsterdam : Elsevier

Staff View

ISSN:	0006-291X
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Chemistry and Pharmacology Physics
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1006/bbrc.1994.1141

Articles: DFG German National Licenses

12

Use of polymerase chain reaction catalyzed by Taq DNA polymerase for site-specific mutagenesis

Kadowaki, H. ; Kadowaki, T. ; Wondisford, F.E. ; Taylor, S.I.

Amsterdam : Elsevier

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ISSN:	0378-1119
Keywords:	Recombinant DNA ; cloning ; gene amplification ; insulin receptor ; oligodeoxyribonucleotide primers ; plasmid
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0378-1119(89)90018-8

Articles: DFG German National Licenses

13

Alteration in growth, cell morphology, and cytoskeletal structures of KB cells induced by epidermal growth factor and transforming growth factor-β

Koyasu, S. ; Kadowaki, T. ; Nishida, E. ; Tobe, K. ; Abe, E. ; Kasuga, M. ; Sakai, H. ; Yahara, I.

Amsterdam : Elsevier

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ISSN:	0014-4827
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0014-4827(88)90125-5

Articles: DFG German National Licenses

14

Rapid stimulation of fluid-phase endocytosis and exocytosis by insulin, insulin-like growth factor-I, and epidermal growth factor in KB cells

Miyata, Y. ; Hoshi, M. ; Koyasu, S. ; Kadowaki, T. ; Kasuga, M. ; Yahara, I. ; Nishida, E. ; Sakai, H.

Amsterdam : Elsevier

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ISSN:	0014-4827
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0014-4827(88)90379-5

Articles: DFG German National Licenses

15

Activation of MAP kinase and enhanced phosphorylation of the 350-kDa protein by mitogenic stimuli in quiescent Balb/c 3T3 cells

Kawakami, M. ; Nishida, E. ; Tobe, K. ; Hoshi, M. ; Kadowaki, T. ; Kasuga, M. ; Sakai, H.

Amsterdam : Elsevier

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ISSN:	0014-4827
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0014-4827(91)90545-6

Articles: DFG German National Licenses

16

Hypoxic depression of mitochondrial mRNA levels in Hela cell

Kadowaki, T. ; Kitagawa, Y.

Amsterdam : Elsevier

Staff View

ISSN:	0014-4827
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0014-4827(91)90182-T

Articles: DFG German National Licenses

17

Enhanced transcription of mitochondrial genes after growth stimulation and glucocorticoid treatment of Reuber hepatoma H-35

Kadowaki, T. ; Kitagawa, Y.

Amsterdam : Elsevier

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ISSN:	0014-5793
Keywords:	(Reuber hepatoma H-35) ; Dexamethasone ; Mitochondrial gene ; Transcription
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Chemistry and Pharmacology Physics
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0014-5793(88)81354-1

Articles: DFG German National Licenses

18

Decomposition of the surface carbide on Ni(001) induced by copper adsorption and surface segregation of carbon

Tochihara, H. ; Pomprasit, A. ; Kadowaki, T. ; Mizuno, S. ; Minagawa, H. ; Hayakawa, K. ; Toyoshima, I.

Amsterdam : Elsevier

Staff View

ISSN:	0039-6028
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Physics
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0039-6028(91)90765-K

Articles: DFG German National Licenses

19

Formation of a linear LiOH compound on Cu(001): reaction of H"2O with Li adatoms at low coverages

Mizuno, S. ; Tochihara, H. ; Kadowaki, T. ; Minagawa, H. ; Hayakawa, K. ; Toyoshima, I. ; Oshima, C.

Amsterdam : Elsevier

Staff View

ISSN:	0039-6028
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Physics
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0039-6028(92)90169-7

Articles: DFG German National Licenses

20

Reaction of triorganostibine sulfides with stable tintin bonds

Otera, J. ; Kadowaki, T. ; Okawara, R.

Amsterdam : Elsevier

Staff View

ISSN:	0022-328X
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Chemistry and Pharmacology
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/S0022-328X(00)87774-8

Articles: DFG German National Licenses

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